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Journal Articles

Final Results from Phase 1 Study of Briquilimab, an Anti-CD117 Monoclonal Antibody, in Combination with Low Dose Irradiation and Fludarabine Conditioning, Shows Durable Remissions in Older Adults with Acute Myeloid Leukemia in Complete Remission and Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Cell Transplantation

Arpita Gandhi, Andrew Artz, Catherine J. Lee, Ankur Varma, Bart L. Scott, Hye-Sook Kwon, Minyoung Youn, Chikako Yanagiba, Jeyakavitha Arulprakasam, Anne Le, Judith Shizuru, Wendy W Pang, Lori S. Muffly
Journal: Blood
Blood (2023) 142 (Supplement 1): 470.
https://doi.org/10.1182/blood-2023-185533
Published: 2023
Journal Articles

Targeting of CD25+ Activated T Cells in Gvhd-Associated Marrow Suppression and Cytopenias

Tami D. John, Laura Valine, Giulia Barbarito, Hye-Sook Kwon, Sally Arai, Beth Martin-Kool, Radhika Kumari, Judith Shizuru, Jean S. Oak, Robertson Parkman, Alice Bertaina, Kenneth I. Weinberg
Journal: Blood
Blood (2023) 142 (Supplement 1): 7033.
https://doi.org/10.1182/blood-2023-190968
Published: 2023
Journal Articles

JSP191 As a Single-Agent Conditioning Regimen Results in Successful Engraftment, Donor Myeloid Chimerism, and Production of Donor Derived Naïve Lymphocytes in Patients with Severe Combined Immunodeficiency (SCID)

Rajni Agarwal, Christopher C. Dvorak, Susan Prockop, Hye-Sook Kwon, Janel R Long-Boyle, Anne Le, Janice W Brown, Elisabeth Merkel, Kenny Truong, Brenda Velasco, Kavitha Arulprakasam, Nicole Harada, Kirstin A Dougall, Susan S Prohaska, Wendy W Pang, Kevin N. Heller, Irving L Weissman, Morton J Cowan, Aaron C. Logan, Richard J O'Reilly, Robertson Parkman, Ken I. Weinberg, Maria Grazia Roncarolo, Judith A Shizuru
Journal: Blood
Blood (2021) 138 (Supplement 1): 554.
https://doi.org/10.1182/blood-2021-153074
Published: 2021
Journal Articles

Heterogeneity of Hematopoietic Stem and Progenitor Cell (HSPC) Composition in Αβ T-Cell/CD19 B-Cell Depleted Peripheral Blood Cell Stem Cell (PBSC) Transplant Grafts and Correlation with Immune and Hematopoietic Recovery

Giulia Barbarito, Beruch Dejene, BS, David C Shyr, MD, Gopin Saini, MBBS, Linda Oppizzi, BS, Sruthi Mantri, Hye-Sook Kwon, PhD, Matthew H. Porteus, MD PhD, Kenneth I. Weinberg, MD, Alice Bertaina, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-143214
Published: 2020
Journal Articles

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Rajni Agarwal, MD, Kenneth I. Weinberg, MD, Hye-Sook Kwon, PhD, Anne Le, Janel R Long-Boyle, PharmD, PhD, Donald B. Kohn, MD, Kathryn Bradford, MD, Satiro De Oliveira, MD, Alice Bertaina, MD PhD, Agnieszka Czechowicz, MDPhD, Matt Porteus, MD PhD, David C Shyr, MD, Katja G Weinacht, MD PhD, Ami J Shah, MD, Melissa Mavers, MD PhD, Elisabeth Merkel, RN, Janice W Brown, MD, Christopher C. Dvorak, MD, Robertson Parkman, MD, Maria Grazia Roncarolo, MD, Judith A Shizuru, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-137762
Published: 2020
Journal Articles

Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency

Rajni Agarwal, MD, Christopher C. Dvorak, MD, Hye-Sook Kwon, PhD, Janel R Long-Boyle, PharmD, PhD, Susan S Prohaska, PhD MS, Janice W Brown, MD, Anne Le, Alyssa Guttman-Klein, Irving L Weissman, MD, Morton J Cowan, MD, Aaron C. Logan, MD PhD, Kenneth I. Weinberg, MD, Robertson Parkman, MD, Maria-Grazia Roncarolo, MD, Judith A Shizuru, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 800.
https://doi.org/10.1182/blood-2019-126239
Published: 2019
Journal Articles

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Hye-Sook Kwon, Aaron C. Logan, Akanksha Chhabra, Wendy W. Pang, Agnieszka Czechowicz, Keri Tate, Alan Le, Jessica Poyser, Roger Hollis, Benjamin V. Kelly, Donald B. Kohn, Irving L. Weissman, Susan S. Prohaska, Judith A. Shizuru
Journal: Blood
Blood (2019) 133 (19): 2104–2108.
https://doi.org/10.1182/blood-2018-06-853879
Published: 2019
Includes: Supplemental data
Journal Articles

Foxp3 + regulatory T Cells Maintain Bone Marrow Microenvironment for B Cell Differentiation from Hematopoietic Stem Cells

Hidekazu Nishikii, MD PhD, Antonio Pierini, MD, Yasuhisa Yokoyama, MD,PhD, Takaharu Kimura, MD PhD, Hye-Sook Kwon, PhD, Maite Alvarez, PhD, Jeanette Baker, PhD, Judith Shizuru, MD PhD, Joy Wu, MD PhD, Shigeru Chiba, MD, PhD, Robert S. Negrin, MD
Journal: Blood
Blood (2016) 128 (22): 431.
https://doi.org/10.1182/blood.V128.22.431.431
Published: 2016