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Journal Articles

Loss of cell cycle regulators RB1 and CDKN2A/2B induces CLL with distinct disease kinetics in murine models and shows distinct outcomes in CLL patients

Ivan Negara, Nevenka Ridova, Federico Jauk, Esther Sathya Bama Benjamin, Marija Vujovikj, Claudio Martines, Giulia Felician, Nadica Matevska-Geshkovska, Davide Rossi, Luca Laurenti, Irina Panovska, Aleksandar Dimovski, Dimitar Efremov

Blood (2025) 146 (Supplement 1): 3879.

https://doi.org/10.1182/blood-2025-3879

Published: 2025

Journal Articles

PD-1 expression on richter syndrome tumor cells does not provide a growth advantage in murine or patient-derived xenograft models In Vivo

Ivan Negara, Esther Sathya Bama Benjamin, Giulia Felician, Claudio Martines, Marija Vujovikj, Tiziana Vaisitti, Silvia Deaglio, Aleksandar Dimovski, Luca Laurenti, Dimitar Efremov

Blood (2025) 146 (Supplement 1): 2104.

https://doi.org/10.1182/blood-2025-2104

Published: 2025

Journal Articles

Richter Syndrome-Associated Genetic Lesions in TP53 and the Cell Cycle Inhibitors CDKN2A and CDKN2B Induce Transformation of a CD5+ B Cell Subset Characterized By a Restricted IGHV Repertoire, Autoreactivity and BCR Dependence

Claudio Martines, Supriya Chakraborty, Giulia Felician, Karin Hofmann, Sasha Blasutig, Ivan Negara, Alice Bonato, Marija Vujovikj, Alberto Zamò, Andreas Rosenwald, Aleksandar J Dimovski, Dimitar G Efremov

Blood (2024) 144 (Supplement 1): 759.

https://doi.org/10.1182/blood-2024-207095

Published: 2024