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Jae Hung Shieh
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Journal Articles

Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing By Self-Renewing Hematopoietic Stem and Progenitor Cells

Tomer Itkin, PhD, Chaitanya R Badwe, PhD, Sean Houghton, MSc, Yang Lin, PhD, Ying Liu, PhD, Peipei Guo, PhD, Jesus M Gomez-Salinero, PhD, Fuqiang Geng, PhD, Jae-Hung Shieh, PhD, David Redmond, PhD, Yen-Michael S. Hsu, MD PhD, Brandon Hadland, MD PhD, Shahin Rafii, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 725.
https://doi.org/10.1182/blood-2019-126190
Published: 2019
Journal Articles

Pre-Clinical Evaluation of a Novel DNA Crosslinking Agent, Bo-1055 in B-Cell Lymphoma

Eloisi Caldas Lopes, Fabian Correa, Elizabeth Peguero, Srikanth R. Ambati, MBBS, MD, Jae Hung Shieh, Tsann Long SU, Malcolm A.S. Moore
Journal: Blood
Blood (2014) 124 (21): 5483.
https://doi.org/10.1182/blood.V124.21.5483.5483
Published: 2014
Journal Articles

Improved ex vivo expansion of adult hematopoietic stem cells by overcoming CUL4-mediated degradation of HOXB4

Jennifer Lee, Jae-Hung Shieh, Jianxuan Zhang, Liren Liu, Yue Zhang, Jae Yong Eom, Giovanni Morrone, Malcolm A. S. Moore, Pengbo Zhou
Journal: Blood
Blood (2013) 121 (20): 4082–4089.
https://doi.org/10.1182/blood-2012-09-455204
Published: 2013
Includes: Supplemental data
Journal Articles

Monocytes Modulate Megakaryocyte-Mediated Fibrosis of Bone Marrow Stromal Cells in Vitro

Emil Tom Kuriakose, MD, Jason Shieh, undergraduate, Jae Hung Shieh, PhD, Richard T. Silver, MD, Malcolm A.S. Moore, PhD
Journal: Blood
Blood (2012) 120 (21): 1759.
https://doi.org/10.1182/blood.V120.21.1759.1759
Published: 2012
Journal Articles

Drug Screening of Primary Human Pediatric Pre-B Cell Acute Lymphoblastic Leukemia (pre-B ALL) Cells in Their Stromal Niche

Jae-Hung Shieh, PhD, Tsann-Long Su, Ph.D., Jason Shieh, undergraduate, Malcolm A.S. Moore, PhD
Journal: Blood
Blood (2012) 120 (21): 4295.
https://doi.org/10.1182/blood.V120.21.4295.4295
Published: 2012
Journal Articles

Derivation and Drug Screening of Growth Factors- and Stroma-Dependent Human Multiple Myeloma Cells

Jae-Hung Shieh, PhD, Tsann-Long Su, Ph.D., Jason Shieh, undergraduate, Malcolm A.S. Moore, D. Phil
Journal: Blood
Blood (2012) 120 (21): 5020.
https://doi.org/10.1182/blood.V120.21.5020.5020
Published: 2012
Journal Articles

Anti-Apoptotic Bcl2 and Bcl-Xl Proteins Involved in Stroma-Induced Drug Tolerance to Hsp70 and Hsp90 Inhibitors in Leukemia and B-Cell Lymphoma

Eloisi Caldas Lopes, Fabian M Correa, Ling-Bo Shen, Jae-Hung Shieh, PhD, Tony Taldone, PhD, Gabriela Chiosis, PhD, Malcolm A.S. Moore, PhD
Journal: Blood
Blood (2012) 120 (21): 4900.
https://doi.org/10.1182/blood.V120.21.4900.4900
Published: 2012
Journal Articles

Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics

Kimberly A. Hartwell, PhD, Peter G. Miller, PhD, Alison L. Stewart, PhD, Alissa R. Kahn, MD, David J. Logan, PhD, Joseph Negri, Mildred Duvet, Shrikanta Chattopadhyay, MD, Sebastian Shterental, Lisa P Chu, Jae Hung Shieh, PhD, Marcus Jaeraas, MD, Vladimir Dancik, PhD, Rajiv Narayan, PhD, Christina Huang, J Erika Haydu, Siddhartha Mukherjee, MD, PhD, Alykhan F Shamji, PhD, Nicola J Tolliday, PhD, Anne E. Carpenter, PhD, Stuart L. Schreiber, PhD, Andrew M. Stern, PhD, Malcolm AS Moore, D Phil, David T. Scadden, MD, Benjamin L. Ebert, MD, D.Phil, Todd R. Golub, MD
Journal: Blood
Blood (2011) 118 (21): 760.
https://doi.org/10.1182/blood.V118.21.760.760
Published: 2011
Journal Articles

In Vitro Culture Reveals Microenvironment-Dependent Growth, Heterogeneity and Hierarchical Structure of Primary Human Pediatric Pre-B Cell Acute Lymphoblastic Leukemia (pre-B ALL) Cells

Jae Hung Shieh, PhD, Peter G Steinherz, MD, Jason Shieh, Malcolm A.S. Moore, D.Phil
Journal: Blood
Blood (2011) 118 (21): 1483.
https://doi.org/10.1182/blood.V118.21.1483.1483
Published: 2011
Journal Articles

A Novel in Vitro Model of Focal Fibrosis in Bone Marrow Stromal Co-Culture of CD34+ Cells From Patients with Idiopathic Myelofibrosis.

Jae Hung Shieh, PhD, Richard T. Silver, MD, Fernando Adriano, Malcolm Moore, DPhil
Journal: Blood
Blood (2009) 114 (22): 2896.
https://doi.org/10.1182/blood.V114.22.2896.2896
Published: 2009
Journal Articles

Generation of Human T/NK Cell Precursors for Adoptive Transfer To Enhance Immune Reconstitution in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.

Sonali Chaudhury, MD, Johannes Zakarzewski, PhD, Jae-Hung Shieh, PhD, Marcel van der Brink, MD PhD, Malcolm A.S. Moore, DPhil
Journal: Blood
Blood (2006) 108 (11): 3209.
https://doi.org/10.1182/blood.V108.11.3209.3209
Published: 2006
Journal Articles

Ubiquitin-Proteolytic Control of HOX Homeodomain Proteins.

Jianxuan Zhang, Jae-Hung Shieh, Liren Liu, Magdalena Plasilova, Yue Zhang, Gianni Morrone, Malcolm A.S. Moore, Pengbo Zhou
Journal: Blood
Blood (2006) 108 (11): 1121.
https://doi.org/10.1182/blood.V108.11.1121.1121
Published: 2006
Journal Articles

Depletion of NUP98: A Common Leukemogenetic Mechanism in AML?

Magdalena Plasilova, PhD, MD, Ky Chung, MD, Jae Hung Shieh, PhD, Rachel J. Fields, Giovanni Morrone, MD, Amy Chadburn, MD, Daniel M. Knowles, MD, Pengbo Zhou, PhD, Malcolm A.S. Moore, PhD
Journal: Blood
Blood (2005) 106 (11): 667.
https://doi.org/10.1182/blood.V106.11.667.667
Published: 2005
Journal Articles

CUL-4A Short Hairpin RNA (shRNA) Impairs Normal Hematopoiesis of Human Cord Blood CD34 + Cells In Vitro and In Vivo .

Jae Hung Shieh, PhD, Jianxuan Zhang, PhD, Xiaoling Lu, Pengbo Zhou, PhD, Malcolm A.S. Moore, Dr of Phil
Journal: Blood
Blood (2005) 106 (11): 2270.
https://doi.org/10.1182/blood.V106.11.2270.2270
Published: 2005
Journal Articles

Genetic and Functional Characterization of Isolated Stromal Cell Lines from the Aorta-Gonado-Mesonephros (AGM)-Region.

Katja C. Weisel, M.D., Ying Gao, Ph.D., Jae-Hung Shieh, Ph.D., Lothar Kanz, M.D., Malcolm A.S. Moore, D. Phil.
Journal: Blood
Blood (2004) 104 (11): 2328.
https://doi.org/10.1182/blood.V104.11.2328.2328
Published: 2004
Journal Articles

Plasma elevation of stromal cell–derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

Koichi Hattori, Beate Heissig, Kei Tashiro, Tasuku Honjo, Masatoshi Tateno, Jae-Hung Shieh, Neil R. Hackett, Mannix S. Quitoriano, Ronald G. Crystal, Shahin Rafii, Malcolm A. S. Moore
Journal: Blood
Blood (2001) 97 (11): 3354–3360.
https://doi.org/10.1182/blood.V97.11.3354
Published: 2001