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James J. Garnsey
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Journal Articles

MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphoma

Michael A. Milhollen, Tary Traore, Jennifer Adams-Duffy, Michael P. Thomas, Allison J. Berger, Lenny Dang, Lawrence R. Dick, James J. Garnsey, Erik Koenig, Steven P. Langston, Mark Manfredi, Usha Narayanan, Mark Rolfe, Louis M. Staudt, Teresa A. Soucy, Jie Yu, Julie Zhang, Joseph B. Bolen, Peter G. Smith
Journal: Blood
Blood (2010) 116 (9): 1515–1523.
https://doi.org/10.1182/blood-2010-03-272567
Published: 2010
Includes: Supplemental data
Journal Articles

Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia

Brief Report
Ronan T. Swords, Kevin R. Kelly, Peter G. Smith, James J. Garnsey, Devalingam Mahalingam, Ernest Medina, Kelli Oberheu, Swaminathan Padmanabhan, Michael O'Dwyer, Steffan T. Nawrocki, Francis J. Giles, Jennifer S. Carew
Journal: Blood
Blood (2010) 115 (18): 3796–3800.
https://doi.org/10.1182/blood-2009-11-254862
Published: 2010
Includes: Supplemental data
Journal Articles

Pre-Clinical Antitumor activity of MLN4924, An Inhibitor of NEDD8-Activating Enzyme (NAE), in a Novel Primary Human DLBCL Xenograft Model.

Tary Traore, James J. Garnsey, Erik Koenig, Allison J Berger, Mark G Manfredi, PhD, Lilli Petruzzelli, MD, PhD, Peter G. Smith, PhD
Journal: Blood
Blood (2009) 114 (22): 927.
https://doi.org/10.1182/blood.V114.22.927.927
Published: 2009
Journal Articles

MLN4924, a Novel Small Molecule Inhibitor of Nedd8-Activating Enzyme, Demonstrates Potent Anti-Tumor Activity in Diffuse Large B-Cell Lymphoma

Michael Milhollen, MSc, Usha Narayanan, Allison J Berger, PhD, Michael Thomas, Tary Traore, Jie Yu, Julie Zhang, Erik Koenig, James J. Garnsey, Steven P. Langston, Teresa A Soucy, PhD, Peter G Smith, PhD
Journal: Blood
Blood (2008) 112 (11): 606.
https://doi.org/10.1182/blood.V112.11.606.606
Published: 2008