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Journal Articles

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Soracha E Ward, BSc, Jamie M O'Sullivan, Sonia Aguila Martinez, BSc, PhD, Clive Drakeford, BSc, Thomas Anthony Jude McKinnon, BSc, PhD, Alain Chion, BSc, PhD, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 980.

https://doi.org/10.1182/blood-2018-99-114775

Published: 2018

Journal Articles

The Irish Personalized Approach to the Treatment of Haemophilia (iPATH) - Determinants of Inter-Individual Variation in FVIII Pharmacokinetics

Michelle Lavin, MB, PhD FRCPath, Niamh Larkin, Anjali Patel, Evelyn Singleton, Mary Byrne, Kevin Ryan, MB, FRCPath, Niamh M O'Connell, MB, PhD FRCPath, Birgit M Reipert, Steven Pipe, Peter L Turecek, PhD, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 1190.

https://doi.org/10.1182/blood-2018-99-112850

Published: 2018

Journal Articles

Site-Directed Pegylation at Specific Sites Significantly Prolongs the Half-Life of A1A2A3-VWF By Markedly Attenuating LRP1-Mediated Clearance

Jamie M O'Sullivan, Judicael Fazavana, PhD, Alain Chan, PhD, Niamh Cooke, PhD, Virginie Terraube, Justin Cohen, PhD, Debra D Pittman, MS, Orla Cunningham, PhD, Matthew Lambert, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 1165.

https://doi.org/10.1182/blood-2018-99-114966

Published: 2018

Journal Articles

The Low Von Willebrand Factor in Ireland Cohort Study - Defining Optimal Management for Procedures in Patients with Low VWF (30-50 IU/dL)

Dearbhla Doherty, MB, MRCPI, Anjali Patel, Margaret Nolan, Mary Byrne, Sonia Aguila, PhD, Jamie M O'Sullivan, Kevin Ryan, MB, FRCPath, Niamh M O'Connell, MB, PhD FRCPath, Michelle Lavin, MB, PhD FRCPath, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 1178.

https://doi.org/10.1182/blood-2018-99-115946

Published: 2018

Journal Articles

Younger Age at Diagnosis Is Associated with an Increased Risk of Venous Thromboembolism in Multiple Myeloma

Aisling Barrett, John Quinn, MD PhD, Siobhan Glavey, MD PhD, Jeremy Sargent, FRCPath, Michelle Lavin, MB, PhD FRCPath, Patrick Thornton, MB, FRCPath, James S O'Donnell, MD PhD, Philip Murphy, MD

Blood (2018) 132 (Supplement 1): 1223.

https://doi.org/10.1182/blood-2018-99-116148

Published: 2018

Journal Articles

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

Michelle Lavin, MB FRCPath, Sonia Aguila, PhD, Sonja Schneppenheim, MD, Niall Dalton, BSc, Jamie M O'Sullivan, PhD, Niamh M O'Connell, MB, FRCPath, PhD, Kevin M. Ryan, MB, Mary Byrne, MSc, Margaret Nolan, BSc, Roger Preston, PhD, Ulrich Budde, MD, Paula D. James, MD, Jorge Di Paola, MD, James S O'Donnell, MD PhD

Blood (2016) 128 (22): 873.

https://doi.org/10.1182/blood.V128.22.873.873

Published: 2016

Journal Articles

N-Linked Glycans within the A1A2A3 Domains of VWF Play a Critical Role in Modulating Macrophage-Mediated Clearance

Alain Chion, Jamie O'Sullivan, Gudmundur Bergsson, Sean Keyes, Orla Rawley, Padraic Fallon, PhD, Nico van Rooijen, PhD, Michael Laffan, MD, Thomas Anthony Jude McKinnon, PhD, Teresa Brophy, James S O'Donnell, MD PhD

Blood (2014) 124 (21): 469.

https://doi.org/10.1182/blood.V124.21.469.469

Published: 2014

Journal Articles

A Novel Role for Von Willebrand Factor in the Pathogenesis of Experimental Cerebral Malaria

Niamh O'Regan, Kristina Gegenbauer, Jamie O'Sullivan, Alister Craig, Padraic Fallon, PhD, Owen Smith, MD, James S O'Donnell, MD PhD

Blood (2014) 124 (21): 97.

https://doi.org/10.1182/blood.V124.21.97.97

Published: 2014

Journal Articles

Identification Of Galectin-1 and Galectin-3 As Novel Binding Partners For Factor VIII

Jamie O' Sullivan, Orla Rawley, Vince Jenkins, PhD, Alain Chion, PhD, Teresa M Brophy, PhD, James S O'Donnell, MD, PhD

Blood (2013) 122 (21): 28.

https://doi.org/10.1182/blood.V122.21.28.28

Published: 2013

Journal Articles

A Critical Role for N- and O-Linked Carbohydrates In Modulating Von Willebrand Factor Clearance In Vivo

Emily McRae, Orla Rawley, Hendrik Nel, PhD, Rachel Therese McGrath, Gudmundur Bergsson, PhD, Alain Chan, PhD, Roger Preston, PhD, Nico van Rooijen, PhD, Padraic Fallon, James S O'Donnell, MD, PhD

Blood (2011) 118 (21): 382.

https://doi.org/10.1182/blood.V118.21.382.382

Published: 2011

Journal Articles

Specific N- and O-Linked Carbohydrate Structures Mediate Von Willebrand Factor Interaction with Galectins -1 and -3

Orla Rawley, Jamie O'Sullivan, Gudmundur Bergsson, PhD, Alain Chan, PhD, Rachel Therese McGrath, Maartje van den Biggelaar, Jan Voorberg, Vince Jenkins, PhD, James S O'Donnell, MD, PhD

Blood (2011) 118 (21): 2234.

https://doi.org/10.1182/blood.V118.21.2234.2234

Published: 2011

Journal Articles

Defining the Molecular Mechanisms Responsible for the ABO High Expresser Phenotype.

Diarmaid O Donghaile, MD, Vince P Jenkins, PhD, Rachel McGrath, BSc, Lisa Preston, MSc, Roger JS Preston, PhD, William G Murphy, James S O'Donnell, MD, PhD

Blood (2009) 114 (22): 2119.

https://doi.org/10.1182/blood.V114.22.2119.2119

Published: 2009

Journal Articles

Terminal α2-6 Linked Sialic Acid Expression On VWF Specifically Enhances Proteolysis by ADAMTS13.

Rachel Therese McGrath, Thomas A J McKinnon, Barry Byrne, Richard O'Kennedy, Michael Laffan, Emily McRae, Roger JS Preston, PhD, James S O'Donnell, MD, PhD

Blood (2009) 114 (22): 30.

https://doi.org/10.1182/blood.V114.22.30.30

Published: 2009

Journal Articles

A Single Amino Acid Substitution (I18V) in the Gla Domain of Activated Protein C Markedly Impairs Ability of PE and GlyCer to Enhance Anticoagulant Activity

Jennifer Johnson, BSc, Fionnuala Ni Ainle, MD, Shona Harmon, PhD, James S O’Donnell, MD, PhD, Roger JS Preston, PhD

Blood (2008) 112 (11): 3071.

https://doi.org/10.1182/blood.V112.11.3071.3071

Published: 2008

Journal Articles

Severe Plasmodium Falciparum Malaria Is Associated with Circulating Ultra-Large Von Willebrand Multimers and ADAMTS13 Inhibition

Deirdre Larkin, PhD, Vince P Jenkins, PhD, James Bunn, MD, Alister G Craig, PhD, Roger JS Preston, PhD, Cynthia Donkor, George E Grau, PhD, Jan A van Mourik, PhD, James S O’Donnell, MD, PhD

Blood (2008) 112 (11): 3918.

https://doi.org/10.1182/blood.V112.11.3918.3918

Published: 2008

Journal Articles

Enhancement of the Anticoagulant Properties of Protamine Sulphate by Activated Protein C

Fionnuala Ni Ainle, MD, Roger JS Preston, PhD, Vince P Jenkins, PhD, Jennifer A Johnson, BSc, Shona Harmon, PhD, O. Smith, Barry White, MD, James S O’Donnell, MD, PhD

Blood (2008) 112 (11): 22.

https://doi.org/10.1182/blood.V112.11.22.22

Published: 2008

Journal Articles

Platelet Factor 4 Mediates Activated Protein C Resistance by Impairment of Protein S Cofactor Enhancement

Roger JS Preston, PhD, Jennifer A Johnson, BSc, Fionnuala Ni Ainle, MD, Shona Harmon, PhD, Owen P. Smith, MD, Barry White, MD, James S O’Donnell, MD, PhD

Blood (2008) 112 (11): 20.

https://doi.org/10.1182/blood.V112.11.20.20

Published: 2008

Journal Articles

Dissociation of Activated Protein C Functions by Elimination of Protein S Cofactor Enhancement

Roger JS Preston, PhD, Shona Harmon, PhD, Fionnuala B Ni Ainle, MD, Jennifer A Johnson, BSc, Moya Cunningham, MD, O. Smith, Barry White, MD, James S O’Donnell, MD, PhD

Blood (2008) 112 (11): 21.

https://doi.org/10.1182/blood.V112.11.21.21

Published: 2008

NARROW

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

The Irish Personalized Approach to the Treatment of Haemophilia (iPATH) - Determinants of Inter-Individual Variation in FVIII Pharmacokinetics

Site-Directed Pegylation at Specific Sites Significantly Prolongs the Half-Life of A1A2A3-VWF By Markedly Attenuating LRP1-Mediated Clearance

The Low Von Willebrand Factor in Ireland Cohort Study - Defining Optimal Management for Procedures in Patients with Low VWF (30-50 IU/dL)

Younger Age at Diagnosis Is Associated with an Increased Risk of Venous Thromboembolism in Multiple Myeloma

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

N-Linked Glycans within the A1A2A3 Domains of VWF Play a Critical Role in Modulating Macrophage-Mediated Clearance

A Novel Role for Von Willebrand Factor in the Pathogenesis of Experimental Cerebral Malaria

Identification Of Galectin-1 and Galectin-3 As Novel Binding Partners For Factor VIII

A Critical Role for N- and O-Linked Carbohydrates In Modulating Von Willebrand Factor Clearance In Vivo

Specific N- and O-Linked Carbohydrate Structures Mediate Von Willebrand Factor Interaction with Galectins -1 and -3

Defining the Molecular Mechanisms Responsible for the ABO High Expresser Phenotype.

Terminal α2-6 Linked Sialic Acid Expression On VWF Specifically Enhances Proteolysis by ADAMTS13.

A Single Amino Acid Substitution (I18V) in the Gla Domain of Activated Protein C Markedly Impairs Ability of PE and GlyCer to Enhance Anticoagulant Activity

Severe Plasmodium Falciparum Malaria Is Associated with Circulating Ultra-Large Von Willebrand Multimers and ADAMTS13 Inhibition

Enhancement of the Anticoagulant Properties of Protamine Sulphate by Activated Protein C

Platelet Factor 4 Mediates Activated Protein C Resistance by Impairment of Protein S Cofactor Enhancement

Dissociation of Activated Protein C Functions by Elimination of Protein S Cofactor Enhancement

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American Society of Hematology

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ASH Publications

American Society of Hematology

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