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Journal Articles

SLN140 a Small Interfering RNA Targeting Protein S Improves Hemostasis Potency in Hemophilia

Raja Eladnani Prince, Ute Schaeper, Julia Aretz, Bojun Li, Maria Desiré Reina Caro, Kristina vrotniakaite-Bajerciene, Mona Eisermann, Sibylle Dames, Kathrin Löffner, Alberto Martinez, Michael Laffan, Josefin Ahnstrom, Anne Angelillo-Scherrer

Blood (2022) 140 (Supplement 1): 1670–1671.

https://doi.org/10.1182/blood-2022-169029

Published: 2022

Journal Articles

Do Children with Immune Thrombocytopenia Have Cerebral Microbleeds?

Alice C J Hart, Ana Maria Cabrera, Camelia Vladescu, Sobia Mustafa, Richard Syzdlo, Rocel C. Saputil, Michelle MH Tan, Amna Malik, David Sharp, Pedro Vicente, Albert Busza, Michael Laffan, Anastasia Gontsarova, Adam Waldman, Nichola Cooper

Blood (2022) 140 (Supplement 1): 48–49.

https://doi.org/10.1182/blood-2022-158176

Published: 2022

Journal Articles

Anticoagulation Practice, Recurrent Thrombosis, and Major Bleeding in Antiphospholipid Syndrome- a Multicentre Observational Study in the United Kingdom

Christina Crossette-Thambiah, Indika Rajakaruna, Zain Odho, Andrew Doyle, Karen Breen, Michael Laffan, Deepa Jayakody Arachchillage

Blood (2022) 140 (Supplement 1): 347–349.

https://doi.org/10.1182/blood-2022-166074

Published: 2022

Journal Articles

Relationship between Endogenous, Transgene FVIII Expression and Bleeding Events Following Valoctocogene Roxaparvovec Gene Transfer for Severe Hemophilia A: A Post-Hoc Analysis of the GENEr8-1 Phase 3 Trial

Blood (2021) 138 (Supplement 1): 3972.

https://doi.org/10.1182/blood-2021-144508

Published: 2021

Journal Articles

Examination and Validation of a Patient-Centric Joint Metric: "Problem Joint"; Empirical Evidence from the CHESS US Dataset

Tom Burke, Idaira Rodriguez Santana, PhD, Pratima Chowdary, MD MBBS, MRCP, FRCPATH, Randall Curtis, MBA, Kate Khair, PhD, Michael Laffan, DM, FRCP, FRCPath, Paul McLaughlin, MSc, MMACP, Declan Noone, MSc, Brian O'Mahony, John Pasi, MB, ChB, PhD FRCP, FRCPath, FRCPCH, Mark W Skinner, JD, Jamie O'Hara, MSc

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-140950

Published: 2020

Journal Articles

Prospective Study Reveals Increased Platelet Function Associated with Multiple Myeloma and Its Treatment

Dalia Khan, Joanne Mitchell, Rekha Rana, Neline Kriek, Amanda Unsworth, Tanya Sage, Michael Laffan, DM, FRCP, FRCPath, Susie Shapiro, MD, Anjan Thakurta, Karthik Ramasamy, MBBS, MRCP, FRCPath, PhD, Jonathan Gibbins, BSc, PhD

Blood (2020) 136 (Supplement 1): 21.

https://doi.org/10.1182/blood-2020-140821

Published: 2020

Journal Articles

Efficacy and Safety of Prothrombin Complex Concentrate in Patients Treated with Rivaroxaban or Apixaban Compared to Warfarin Presenting with Major Bleeding

Deepa Jayakody Arachchillage, MD MRCP, FRCPath, Sharon Alavian, Jessica Griffin, MRCP, Kamala Gurung, MRCP, Richard Syzdlo, PhD, Nilanthi Karawitage, Michael Laffan, DM, FRCP, FRCPath

Blood (2018) 132 (Supplement 1): 2535.

https://doi.org/10.1182/blood-2018-99-116432

Published: 2018

Journal Articles

Incidence of Thrombocytopenia and Heparin Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO) Compared to Cardiopulmonary Bypass and the Limited Sensitivity of Pre-Test Probability Score

Deepa Jayakody Arachchillage, MD MRCP, FRCPath, Sanjay Khanna, Christophe Vandenbriele, Jonthan Dutton, Alex Rosenberg, MRCP, FCICM, FFICM, TC Aw, FRCA, Winston Banya, Maurizio Passariello, EDIC, Michael Laffan, DM, FRCP, FRCPath, Stephane Ledot, EDIC, MD, Brijesh Patel, MRCP, FRCA, FFICM , PhD

Blood (2018) 132 (Supplement 1): 2451.

https://doi.org/10.1182/blood-2018-99-119143

Published: 2018

Journal Articles

The Relationship between Thrombin Generation Assay and FVIII Levels in Patients with Mild to Moderate Haemophilia (A)

Pu-Lin Luo, FRCPath, Steven K. Austin, BMedSci, MBBS, Kiran Parmar, MSc, Dan P Hart, PhD MBBChir, FRCPath, FRCP, Michael Laffan, DM, FRCP, FRCPath

Blood (2018) 132 (Supplement 1): 2454.

https://doi.org/10.1182/blood-2018-99-111675

Published: 2018

Journal Articles

Congenital Aspirin-like Defect As a Result of Autosomal Recessive Variants in PTGS1

Suthesh Sivapalaratnam, MD PhD, Hayman Melissa, PhD, Claire Lentaigne, BSc, MB, MRCP, Melissa Chan, PhD, Marilena Crescente, PhD, Harriet Allan, Katherine Wedderburn, Moghees Hanif, Ernest Turro, PhD, Dan P Hart, PhD MBBChir, FRCPath, FRCP, Kathleen Freson, PhD, Kate Downes, PhD, NIHR Bioresource, Willem Ouwehand, MDPhD, Michael Laffan, DM, FRCP, FRCPath, Tim Warner, PhD

Blood (2018) 132 (Supplement 1): 1156.

https://doi.org/10.1182/blood-2018-99-118958

Published: 2018

Journal Articles

Efficacy and Safety of Prothrombin Complex Concentrate in Patients Undergoing Major Cardiac Surgery

Deepa Jayakody Arachchillage, Simona Deplano, Eleanor Dunnett, Steve Owen, Louise Tillyer, Michael Laffan

Blood (2016) 128 (22): 3852.

https://doi.org/10.1182/blood.V128.22.3852.3852

Published: 2016

Journal Articles

Germline Calr exon 9 Variant and Somatic JAK2 V617F Mutation in a Patient with Polycythemia Vera Associated with Late Presentation and Severe Clinical Phenotype

Chieh Lee Wong, Gareth Gerrard, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Jameela Sathar, Liming Liang, Tim Aitman, Letizia Foroni, Michael Laffan

Blood (2016) 128 (22): 5485.

https://doi.org/10.1182/blood.V128.22.5485.5485

Published: 2016

Journal Articles

Differential Expression of Genes Associated with Oncogene-Induced Senescence and Senescence Associated Secretory Phenotype in the Absence of Differential Expression of High Molecular Risk Genes and Genes Associated with JAK-STAT Pathway in Sorted Cells of Patients with Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Andrew Innes, Baoshan Ma, Gareth Gerrard, Zainul Abidin Norziha, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Jameela Sathar, Siew Fen Lye, Letizia Foroni, Tim Aitman, Liming Liang, Jesus Gil, Michael Laffan

Blood (2016) 128 (22): 4283.

https://doi.org/10.1182/blood.V128.22.4283.4283

Published: 2016

Journal Articles

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

Alain Chion, Jamie M. O’Sullivan, Clive Drakeford, Gudmundur Bergsson, Niall Dalton, Sonia Aguila, Soracha Ward, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Lauren Brady, Orla Sheils, Michael Laffan, Thomas A. J. McKinnon, James S. O’Donnell

Blood (2016) 128 (15): 1959–1968.

https://doi.org/10.1182/blood-2016-04-709436

Published: 2016

Includes: Supplemental data

Journal Articles

The N-Linked Glycans of ADAMTS13 Are Critical Determinants of Conformation and Proteolytic Activity

Agata Anna Nowak, MSc, PhD, Michael Laffan, MD, Thomas Anthony Jude McKinnon, PhD

Blood (2015) 126 (23): 1043.

https://doi.org/10.1182/blood.V126.23.1043.1043

Published: 2015

Journal Articles

Gene Expression Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Baoshan Ma, Gareth Gerrard, Martyna Adamowicz-Brice, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Gin Gin Gan, Jameela Sathar, Siew Fen Lye, Letizia Foroni, Tim Aitman, Liming Liang, Michael Laffan

Blood (2015) 126 (23): 5201.

https://doi.org/10.1182/blood.V126.23.5201.5201

Published: 2015

Journal Articles

DNA Methylation Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Baoshan Ma, Martyna Adamowicz-Brice, Gareth Gerrard, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Gin Gin Gan, Jameela Sathar, Letizia Foroni, Tim Aitman, Liming Liang, Michael Laffan

Blood (2015) 126 (23): 5204.

https://doi.org/10.1182/blood.V126.23.5204.5204

Published: 2015

Journal Articles

Targeted Sequencing of Sorted Peripheral Blood Cells Reveals Novel Germline and Somatic Variants in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Gareth Gerrard, Martyna Adamowicz-Brice, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Gin Gin Gan, Jameela Sathar, Baoshan Ma, Liming Liang, Tim Aitman, Letizia Foroni, Michael Laffan

Blood (2015) 126 (23): 5213.

https://doi.org/10.1182/blood.V126.23.5213.5213

Published: 2015

Journal Articles

A Pilot Study of Assessing Cognition in Children with Sickle Cell Disease Using a New Software Package the Cogstate Battery

Jessica Thompson, Catherine Mkandawire, Subarna Chakravorty, MDPhD, Michael Laffan, MD

Blood (2015) 126 (23): 4592.

https://doi.org/10.1182/blood.V126.23.4592.4592

Published: 2015

Journal Articles

N-Linked Glycans within the A1A2A3 Domains of VWF Play a Critical Role in Modulating Macrophage-Mediated Clearance

Alain Chion, Jamie O'Sullivan, Gudmundur Bergsson, Sean Keyes, Orla Rawley, Padraic Fallon, PhD, Nico van Rooijen, PhD, Michael Laffan, MD, Thomas Anthony Jude McKinnon, PhD, Teresa Brophy, James S O'Donnell, MD PhD

Blood (2014) 124 (21): 469.

https://doi.org/10.1182/blood.V124.21.469.469

Published: 2014

NARROW

SLN140 a Small Interfering RNA Targeting Protein S Improves Hemostasis Potency in Hemophilia

Do Children with Immune Thrombocytopenia Have Cerebral Microbleeds?

Anticoagulation Practice, Recurrent Thrombosis, and Major Bleeding in Antiphospholipid Syndrome- a Multicentre Observational Study in the United Kingdom

Relationship between Endogenous, Transgene FVIII Expression and Bleeding Events Following Valoctocogene Roxaparvovec Gene Transfer for Severe Hemophilia A: A Post-Hoc Analysis of the GENEr8-1 Phase 3 Trial

Examination and Validation of a Patient-Centric Joint Metric: "Problem Joint"; Empirical Evidence from the CHESS US Dataset

Prospective Study Reveals Increased Platelet Function Associated with Multiple Myeloma and Its Treatment

Efficacy and Safety of Prothrombin Complex Concentrate in Patients Treated with Rivaroxaban or Apixaban Compared to Warfarin Presenting with Major Bleeding

Incidence of Thrombocytopenia and Heparin Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO) Compared to Cardiopulmonary Bypass and the Limited Sensitivity of Pre-Test Probability Score

The Relationship between Thrombin Generation Assay and FVIII Levels in Patients with Mild to Moderate Haemophilia (A)

Congenital Aspirin-like Defect As a Result of Autosomal Recessive Variants in PTGS1

Efficacy and Safety of Prothrombin Complex Concentrate in Patients Undergoing Major Cardiac Surgery

Germline Calr exon 9 Variant and Somatic JAK2 V617F Mutation in a Patient with Polycythemia Vera Associated with Late Presentation and Severe Clinical Phenotype

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

The N-Linked Glycans of ADAMTS13 Are Critical Determinants of Conformation and Proteolytic Activity

Gene Expression Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Polycythemia Vera and Primary Myelofibrosis

DNA Methylation Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

Targeted Sequencing of Sorted Peripheral Blood Cells Reveals Novel Germline and Somatic Variants in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

A Pilot Study of Assessing Cognition in Children with Sickle Cell Disease Using a New Software Package the Cogstate Battery

N-Linked Glycans within the A1A2A3 Domains of VWF Play a Critical Role in Modulating Macrophage-Mediated Clearance

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American Society of Hematology

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American Society of Hematology

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