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Roger J. S. Preston
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Journal Articles

The aptamer BT200 blocks interaction of K1405-K1408 in the VWF-A1 domain with macrophage LRP1

Alain Chion, Ciara Byrne, Ferdows Atiq, Dearbhla Doherty, Sonia Aguila, Judicael Fazavana, Patricia Lopes, Ellie Karampini, Aamir Amin, Roger J. S. Preston, Ross I. Baker, Thomas A. J. McKinnon, Shuhao Zhu, James C. Gilbert, Jonas Emsley, Bernd Jilma, James S. O’Donnell
Journal: Blood
Blood (2024) 144 (13): 1445–1456.
https://doi.org/10.1182/blood.2024024055
Published: 2024
Includes: Supplemental data
Journal Articles

Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies

Ferdows Atiq, Robin Blok, Calvin B. van Kwawegen, Dearbhla Doherty, Michelle Lavin, Johanna G. van der Bom, Niamh M. O'Connell, Joke de Meris, Kevin Ryan, Saskia E. M. Schols, Mary Byrne, Floor C. J. I. Heubel-Moenen, Karin P. M. van Galen, Roger J. S. Preston, Marjon H. Cnossen, Karin Fijnvandraat, Ross I. Baker, Karina Meijer, Paula James, Jorge Di Paola, Jeroen Eikenboom, Frank W. G. Leebeek, James S. O'Donnell
Journal: Blood
Blood (2024) 143 (14): 1414–1424.
https://doi.org/10.1182/blood.2023022457
Published: 2024
Includes: Supplemental data
Journal Articles

New targeted therapy for hemophilia

Roger J. S. Preston
Journal: Blood
Blood (2023) 142 (12): 1032–1034.
https://doi.org/10.1182/blood.2023021385
Published: 2023
Journal Articles

Increased galactose expression and enhanced clearance in patients with low von Willebrand factor

Sonia Aguila, Michelle Lavin, Niall Dalton, Sean Patmore, Alain Chion, George D. Trahan, Kenneth L. Jones, Catriona Keenan, Teresa M. Brophy, Niamh M. O’Connell, Kevin Ryan, Mary Byrne, Margaret Nolan, Anjali Patel, Roger J. S. Preston, Paula James, Jorge Di Paola, Jamie M. O’Sullivan, James S. O’Donnell
Journal: Blood
Blood (2019) 133 (14): 1585–1596.
https://doi.org/10.1182/blood-2018-09-874636
Published: 2019
Includes: Supplemental data
Journal Articles

A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance

Brief Report
Soracha E. Ward, Jamie M. O’Sullivan, Clive Drakeford, Sonia Aguila, Christopher N. Jondle, Jyotika Sharma, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Paul Smyth, Orla Sheils, Alain Chion, James S. O’Donnell
Journal: Blood
Blood (2018) 131 (8): 911–916.
https://doi.org/10.1182/blood-2017-06-787853
Published: 2018
Includes: Supplemental data
Journal Articles

Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels

Clinical Trials & Observations
Michelle Lavin, Sonia Aguila, Sonja Schneppenheim, Niall Dalton, Kenneth L. Jones, Jamie M. O’Sullivan, Niamh M. O’Connell, Kevin Ryan, Barry White, Mary Byrne, Marie Rafferty, Mairead M. Doyle, Margaret Nolan, Roger J. S. Preston, Ulrich Budde, Paula James, Jorge Di Paola, James S. O’Donnell
Journal: Blood
Blood (2017) 130 (21): 2344–2353.
https://doi.org/10.1182/blood-2017-05-786699
Published: 2017
Includes: Supplemental data
Journal Articles

Microbiome influences von Willebrand factor

Roger J. S. Preston, James S. O’Donnell
Journal: Blood
Blood (2017) 130 (4): 393–395.
https://doi.org/10.1182/blood-2017-06-789156
Published: 2017
Journal Articles

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

Alain Chion, Jamie M. O’Sullivan, Clive Drakeford, Gudmundur Bergsson, Niall Dalton, Sonia Aguila, Soracha Ward, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Lauren Brady, Orla Sheils, Michael Laffan, Thomas A. J. McKinnon, James S. O’Donnell
Journal: Blood
Blood (2016) 128 (15): 1959–1968.
https://doi.org/10.1182/blood-2016-04-709436
Published: 2016
Includes: Supplemental data
Journal Articles

Emerging roles for hemostatic dysfunction in malaria pathogenesis

Jamie M. O’Sullivan, Roger J. S. Preston, Niamh O’Regan, James S. O’Donnell
Journal: Blood
Blood (2016) 127 (19): 2281–2288.
https://doi.org/10.1182/blood-2015-11-636464
Published: 2016
Journal Articles

A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria

Niamh O’Regan, Kristina Gegenbauer, Jamie M. O’Sullivan, Sanaz Maleki, Teresa M. Brophy, Niall Dalton, Alain Chion, Padraic G. Fallon, Georges E. Grau, Ulrich Budde, Owen P. Smith, Alister G. Craig, Roger J. S. Preston, James S. O’Donnell
Journal: Blood
Blood (2016) 127 (9): 1192–1201.
https://doi.org/10.1182/blood-2015-07-654921
Published: 2016
Includes: Supplemental data
Journal Articles

Activated protein C β-glycoform promotes enhanced noncanonical PAR1 proteolysis and superior resistance to ischemic injury

Brief Report
Eimear M. Gleeson, María G. Dichiara, Agustina Salicio, Louise M. Quinn, Clive Drakeford, Shane E. Russell, Patrick T. Walsh, Josune Orbe, José Hermida, Owen P. Smith, James S. O’Donnell, Ramón Montes, Roger J. S. Preston
Journal: Blood
Blood (2015) 126 (7): 915–919.
https://doi.org/10.1182/blood-2015-03-632877
Published: 2015
Includes: Supplemental data
Journal Articles

Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis

Brief Report
Rachel T. McGrath, Maartje van den Biggelaar, Barry Byrne, Jamie M. O’Sullivan, Orla Rawley, Richard O’Kennedy, Jan Voorberg, Roger J. S. Preston, James S. O’Donnell
Journal: Blood
Blood (2013) 122 (25): 4107–4110.
https://doi.org/10.1182/blood-2013-04-496851
Published: 2013
Journal Articles

Elucidating the role of carbohydrate determinants in regulating hemostasis: insights and opportunities

Roger J. S. Preston, Orla Rawley, Eimear M. Gleeson, James S. O’Donnell
Journal: Blood
Blood (2013) 121 (19): 3801–3810.
https://doi.org/10.1182/blood-2012-10-415000
Published: 2013
Journal Articles

Expression of terminal α2-6–linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS13

Rachel T. McGrath, Thomas A. J. McKinnon, Barry Byrne, Richard O'Kennedy, Virginie Terraube, Emily McRae, Roger J. S. Preston, Mike A. Laffan, James S. O'Donnell
Journal: Blood
Blood (2010) 115 (13): 2666–2673.
https://doi.org/10.1182/blood-2009-09-241547
Published: 2010
Journal Articles

Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation

Fionnuala Ni Ainle, Roger J. S. Preston, P. Vincent Jenkins, Hendrik J. Nel, Jennifer A. Johnson, Owen P. Smith, Barry White, Padraic G. Fallon, James S. O'Donnell
Journal: Blood
Blood (2009) 114 (8): 1658–1665.
https://doi.org/10.1182/blood-2009-05-222109
Published: 2009
Journal Articles

APC stripped bare

Roger J. S. Preston, David A. Lane
Journal: Blood
Blood (2004) 104 (6): 1595–1596.
https://doi.org/10.1182/blood-2004-06-2426
Published: 2004