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Journal Articles

Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies

Ferdows Atiq, Robin Blok, Calvin B. van Kwawegen, Dearbhla Doherty, Michelle Lavin, Johanna G. van der Bom, Niamh M. O'Connell, Joke de Meris, Kevin Ryan, Saskia E. M. Schols, Mary Byrne, Floor C. J. I. Heubel-Moenen, Karin P. M. van Galen, Roger J. S. Preston, Marjon H. Cnossen, Karin Fijnvandraat, Ross I. Baker, Karina Meijer, Paula James, Jorge Di Paola, Jeroen Eikenboom, Frank W. G. Leebeek, James S. O'Donnell
Journal: Blood
Blood (2024) 143 (14): 1414–1424.
https://doi.org/10.1182/blood.2023022457
Published: 2024
Includes: Supplemental data
Journal Articles

Age Regulates Desmopressin Responses in Patients with Low Von Willebrand Factor and Type 1 Von Willebrand Disease in the Lovic and Win Studies

Ferdows Atiq, Robin Blok, Calvin Van Kwawegen, Dearbhla Doherty, Michelle Lavin, Johanna G. Van Der Bom, Niamh O'Connell, Joke De Meris, Kevin Ryan, Saskia Schols, Mary Byrne, Floor Moenen, Karin PM Van Galen, Roger J.S Preston, Karin Fijnvandraat, Ross Baker, Karina Meijer, Paula James, Jorge Di Paola, Jeroen Eikenboom, James S. O'Donnell, Frank W.G. Leebeek
Journal: Blood
Blood (2023) 142 (Supplement 1): 510.
https://doi.org/10.1182/blood-2023-184734
Published: 2023
Journal Articles

The Relationship between Low Von Willebrand Factor, Type 1 Von Willebrand Disease and Ageing - Novel Insights from the Lovic and Win Cohort Studies

Ferdows Atiq, Robin Blok, Calvin Van Kwawegen, Dearbhla Doherty, Michelle Lavin, Johanna G. Van Der Bom, Niamh O'Connell, Joke De Meris, Kevin Ryan, Saskia Schols, Mary Byrne, Floor Moenen, Karin PM Van Galen, Roger J.S Preston, Karin Fijnvandraat, Ross Baker, Karina Meijer, Paula James, Jorge Di Paola, Jeroen Eikenboom, Frank W.G. Leebeek, James S. O'Donnell
Journal: Blood
Blood (2023) 142 (Supplement 1): 509.
https://doi.org/10.1182/blood-2023-181603
Published: 2023
Journal Articles

Bleeding Outcomes in People with Von Willebrand Disease Receiving Antithrombotic Therapy

Aisling Barrett, Catherine Bergin, Mary Byrne, Kevin Ryan, Niamh M O'Connell, James S O'Donnell, Michelle Lavin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3196.
https://doi.org/10.1182/blood-2021-152919
Published: 2021
Journal Articles

A Synthetic Lethal Approach to Eradicate AML Via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors

Sha Li, Anne-Louise Latif, Ashley Newcombe, Kathryn Gilrory, Neil Robertson, Xue Lei, Darren Finlay, PhD, Karina Barbosa, BSc, Helen Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi Delori, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-Ichi Sakamaki, Jennifer Morton, Kevin Ryan, Stephen Tait, Sheela Abraham, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Brian Higgins, Xu Huang, BSc, PhD, Karen Blyth, Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Timothy Chevassut, Aniruddha J. Deshpande, PhD, Karen Keeshan, Peter Adams, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
https://doi.org/10.1182/blood-2020-143079
Published: 2020
Journal Articles

Increased galactose expression and enhanced clearance in patients with low von Willebrand factor

Sonia Aguila, Michelle Lavin, Niall Dalton, Sean Patmore, Alain Chion, George D. Trahan, Kenneth L. Jones, Catriona Keenan, Teresa M. Brophy, Niamh M. O’Connell, Kevin Ryan, Mary Byrne, Margaret Nolan, Anjali Patel, Roger J. S. Preston, Paula James, Jorge Di Paola, Jamie M. O’Sullivan, James S. O’Donnell
Journal: Blood
Blood (2019) 133 (14): 1585–1596.
https://doi.org/10.1182/blood-2018-09-874636
Published: 2019
Includes: Supplemental data
Journal Articles

The Irish Personalized Approach to the Treatment of Haemophilia (iPATH) - Determinants of Inter-Individual Variation in FVIII Pharmacokinetics

Michelle Lavin, MB, PhD FRCPath, Niamh Larkin, Anjali Patel, Evelyn Singleton, Mary Byrne, Kevin Ryan, MB, FRCPath, Niamh M O'Connell, MB, PhD FRCPath, Birgit M Reipert, Steven Pipe, Peter L Turecek, PhD, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1190.
https://doi.org/10.1182/blood-2018-99-112850
Published: 2018
Journal Articles

The Low Von Willebrand Factor in Ireland Cohort Study - Defining Optimal Management for Procedures in Patients with Low VWF (30-50 IU/dL)

Dearbhla Doherty, MB, MRCPI, Anjali Patel, Margaret Nolan, Mary Byrne, Sonia Aguila, PhD, Jamie M O'Sullivan, Kevin Ryan, MB, FRCPath, Niamh M O'Connell, MB, PhD FRCPath, Michelle Lavin, MB, PhD FRCPath, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1178.
https://doi.org/10.1182/blood-2018-99-115946
Published: 2018
Journal Articles

Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels

Clinical Trials & Observations
Michelle Lavin, Sonia Aguila, Sonja Schneppenheim, Niall Dalton, Kenneth L. Jones, Jamie M. O’Sullivan, Niamh M. O’Connell, Kevin Ryan, Barry White, Mary Byrne, Marie Rafferty, Mairead M. Doyle, Margaret Nolan, Roger J. S. Preston, Ulrich Budde, Paula James, Jorge Di Paola, James S. O’Donnell
Journal: Blood
Blood (2017) 130 (21): 2344–2353.
https://doi.org/10.1182/blood-2017-05-786699
Published: 2017
Includes: Supplemental data