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Andrew Davis
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Journal Articles

TL-895, a Highly Selective, Covalent Inhibitor of Bruton's Tyrosine Kinase (BTK), Sensitizes Myeloproliferative Neoplasm (MPN)-Blast Phase Stem Cells to Navtemadlin By Targeting Intrinsic Dysregulated MDM2/p53 and NF-Κb Pathways and Disrupting the Protective Tumor Microenvironment (TME)

Xiaoli Wang, Andrew Davis, Xiaoping Su, Muharrem Muftuoglu, Cecile Krejsa, John Mascarenhas, Michael Andreeff, Ronald Hoffman
Journal: Blood
Blood (2023) 142 (Supplement 1): 4523.
https://doi.org/10.1182/blood-2023-187426
Published: 2023
Journal Articles

Transcriptional and Epigenetic Dysregulation Drives Erythroid and Megakaryocyte Differentiation Bias in the Spleens of Patients with Advanced Myelofibrosis

Rebecca Austin, Madeline Kowalski, Xiaoli Wang, Bettina Nadorp, Audrey Lasry, Zhengxi Sun, Julia Rojo-Tomillo, Andrew Davis, Dimitrios Papaioannou, Rahul Satija, Ioannis Aifantis, Ronald Hoffman
Journal: Blood
Blood (2022) 140 (Supplement 1): 9584–9585.
https://doi.org/10.1182/blood-2022-170220
Published: 2022
Journal Articles

A Synthetic Lethal Approach to Eradicate AML Via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors

Sha Li, Anne-Louise Latif, Ashley Newcombe, Kathryn Gilrory, Neil Robertson, Xue Lei, Darren Finlay, PhD, Karina Barbosa, BSc, Helen Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi Delori, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-Ichi Sakamaki, Jennifer Morton, Kevin Ryan, Stephen Tait, Sheela Abraham, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Brian Higgins, Xu Huang, BSc, PhD, Karen Blyth, Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Timothy Chevassut, Aniruddha J. Deshpande, PhD, Karen Keeshan, Peter Adams, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
https://doi.org/10.1182/blood-2020-143079
Published: 2020