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Anagha Deshpande
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Journal Articles

The role of aging in promoting leukemia progression through cell-intrinsic and cell-extrinsic mechanisms

Free
Marcos Garcia Teneche, Eugene Yui-Ching Chow, Annanya Sethiya, Sha Li, Beatrice Silvestri, Kelly Yichen Li, Marlenne Perales Garcia, Rouven Arnold, Neha Niranjan, Jessica Proulx, Aaron Havas, Armin Gandhi, Michael Alcaraz, Laurence Haddadin, Carolina Cano Macip, Andrew Davis, Aniruddha Deshpande, Anagha Deshpande, Yu Xin Wang, Kevin Yip, Peter Adams
Journal: Blood
Blood (2025) 146 (Supplement 1): 6704.
https://doi.org/10.1182/blood-2025-6704
Published: 2025
Journal Articles

Transcriptional control of leukemogenesis by the chromatin reader SGF29

Free
Karina Barbosa, Anagha Deshpande, Marlenne Perales, Ping Xiang, Rabi Murad, Akula Bala Pramod, Anna Minkina, Neil Robertson, Fiorella Schischlik, Xue Lei, Younguk Sun, Adam Brown, Diana Amend, Irmela Jeremias, John G. Doench, R. Keith Humphries, Eytan Ruppin, Jay Shendure, Prashant Mali, Peter D. Adams, Aniruddha J. Deshpande
Journal: Blood
Blood (2024) 143 (8): 697–712.
https://doi.org/10.1182/blood.2023021234
Published: 2024
Includes: Supplemental data
Journal Articles

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Free
Bo-Rui Chen, Anagha Deshpande, Karina Barbosa, Maria Kleppe, Xue Lei, Narayana Yeddula, Pablo Sánchez Vela, Alexandre Rosa Campos, Robert J. Wechsler-Reya, Anindya Bagchi, Soheil Meshinchi, Connie Eaves, Irmela Jeremias, Torsten Haferlach, David A. Frank, Ze’ev Ronai, Sumit Chanda, Scott A. Armstrong, Peter D. Adams, Ross L. Levine, Aniruddha J. Deshpande
Journal: Blood
Blood (2021) 137 (24): 3403–3415.
https://doi.org/10.1182/blood.2020009023
Published: 2021
Includes: Supplemental data
Journal Articles

High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia

Free
Karina Barbosa, BSc, Anagha Deshpande, PhD, Ping Xiang, PhD, Bo-Rui Chen, PhD, Adam Brown, MSc, Neil Robertson, Younguk Sun, PhD, John Doench, PhD, Peter D Adams, PhD, R. Keith Humphries, MD PhD, Prashant Mali, PhD, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-141412
Published: 2020
Journal Articles

RNF5 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

Free
Ali Khateb, PhD, Anagha Deshpande, PhD, Yongmei Feng, PhD, Ikrame Lazar, PhD, Joo Sang Lee, PhD, Bertrand Fabre, PhD, Yan Li, PhD, Darren Finlay, PhD, Yu Fujita, PhD, Tongwu Zhang, PhD, Ian Pass, PhD, Ido Livneh, PhD, Carol Burian, James R. Mason, MD, Ronit Almog, MD, Nurit Horesh, MD, Yishai Ofran, MD, Kevin Brown, Kristiina Vuori, PhD, Michael Jackson, PhD, Eytan Ruppin, PhD, Aniruddha J. Deshpande, PhD, Ze'ev A. Ronai, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-143352
Published: 2020
Journal Articles

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Free
Bo-Rui Chen, PhD, Anagha Deshpande, PhD, Maria Kleppe, PhD, Narayana Yeddula, PhD, Sunnie Yoh, PhD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD, Sumit Chanda, PhD, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 544.
https://doi.org/10.1182/blood-2018-99-119210
Published: 2018
Journal Articles

Genetic or Pharmacological Inhibition of the Polycomb Group Protein BMI1 Impairs Leukemic Transformation Mediated By the CALM-AF10 Fusion Oncoprotein

Free
Karina O. Barbosa, BSc, Anwesha Ghosh, PhD, Anagha Deshpande, PhD, Sayantanee Dutta, PhD, Scott A. Armstrong, MD PhD, Stefan K. Bohlander, MD, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 762.
https://doi.org/10.1182/blood-2018-99-115552
Published: 2018
Journal Articles

Targeting MYC-Driven B-Cell Lymphoma By Inhibition of the Histone Methyltransferase DOT1L

Free
Anagha Deshpande, PhD, Benson Chen, Parham Ramezani-Rad, PhD, Alessandro Pastore, Luyi Zhao, M.S., Oliver Weigert, MD, Scott A. Armstrong, MD PhD, Robert C Rickert, PhD, Bing Ren, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2839.
https://doi.org/10.1182/blood-2018-99-115475
Published: 2018
Journal Articles

BCR-ABL Transformation Requires Glycogen Synthase 1 (GYS1) Expression for Cell Growth and Increased Glycogen Production

Free
Mamatha M. Reddy, PhD, Anagha Deshpande, PhD, Atsushi Nonami, MD, PhD, Ellen L. Weisberg, PhD, Tirumala K. Chowdary, PhD, James D. Griffin, MD, Martin Sattler, PhD
Journal: Blood
Blood (2012) 120 (21): 1673.
https://doi.org/10.1182/blood.V120.21.1673.1673
Published: 2012
Journal Articles

Kinase Domain Mutations in JAK2V617F Confer Resistance to the Novel JAK2 Inhibitor Ruxolitinib

Free
Anagha Deshpande, PhD, Mamatha M. Reddy, PhD, Georg Schade, Arghya Ray, Ph.D, Tirumala K. Chowdary, PhD, James D. Griffin, MD, Martin Sattler, PhD
Journal: Blood
Blood (2011) 118 (21): 125.
https://doi.org/10.1182/blood.V118.21.125.125
Published: 2011