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Jan H. Beumer
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Journal Articles

A phase 1 study of the amino acid modulator pegcrisantaspase and venetoclax for relapsed or refractory acute myeloid leukemia

Available to Purchase
Clinical Trials & Observations
Yuchen Liu, Dominique R. Bollino, Osman M. Bah, Erin T. Strovel, Tien V. Le, Jinoos Zarrabi, Sunita Philip, Rena G. Lapidus, Maria R. Baer, Sandrine Niyongere, Vu H. Duong, Christine C. Dougherty, Jan H. Beumer, Katherine D. Caprinolo, Farin Kamangar, Ashkan Emadi
Journal: Blood
Blood (2025) 145 (5): 486–496.
https://doi.org/10.1182/blood.2024024837
Published: 2025
Includes: Supplemental data
Journal Articles

A Phase II Study of Dasatinib and Dexamethasone As Primary Therapy Followed By Transplantation for Adults with Newly Diagnosed Ph/ BCR-ABL1 -Positive Acute Lymphoblastic Leukemia (Ph+ ALL): Final Results of Alliance/CALGB Study 10701

Free
Matthew J. Wieduwilt, MD PhD, Jun Yin, PhD, Meir Wetzler, MD, Geoffrey L. Uy, MD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, Michaela Liedtke, MD, Wendy Stock, MD, Jan H Beumer, Ryan J. Mattison, MD, Elizabeth Storrick, Steven Devine, Scott E. Smith, MD PhD, Richard M. Stone, MD, Richard A. Larson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 309.
https://doi.org/10.1182/blood-2018-99-120029
Published: 2018
Journal Articles

A Phase II Study of Dasatinib and Dexamethasone As Primary Therapy Followed By Hematopoietic Cell Transplantation for Adults with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: CALGB Study 10701 (Alliance)

Free
Matthew J. Wieduwilt, MD PhD, Jun Yin, PhD, Meir Wetzler, MD, Geoffrey L. Uy, MD, Bayard L Powell, MD, Jonathan E. Kolitz, MD, Michaela Liedtke, MD, Wendy Stock, MD, Jan H. Beumer, PharmD, PhD, Ryan J. Mattison, MD, Alese Halvorson, Steven M. Devine, MD, Scott Smith, MD PhD, Richard M. Stone, MD, Richard A. Larson, MD
Journal: Blood
Blood (2016) 128 (22): 2782.
https://doi.org/10.1182/blood.V128.22.2782.2782
Published: 2016
Journal Articles

Results from a Phase 1 Study and Expanded Cohort of an Interrupted Dosing Schedule of the Aurora Kinase a Inhibitor MLN8237 Combined with Vorinostat in Lymphoid Malignancies

Free
Tanya Siddiqi, MD, Anna Scuto, PhD, Jan H. Beumer, PharmD, PhD, Joo Y. Song, MD, Paul Frankel, PhD, Chris Ruel, MS, Jacob Cobb, BS, Brian F. Kiesel, BS, Dennis D. Weisenburger, MD, Kevin R. Kelly, MD PhD, Joseph Tuscano, MD, Leslie Popplewell, MD, Stephen J. Forman, MD, Richard Piekarz, PhD MD, Edward M. Newman, PhD
Journal: Blood
Blood (2015) 126 (23): 2731.
https://doi.org/10.1182/blood.V126.23.2731.2731
Published: 2015
Journal Articles

A Phase 1 Study of the PARP Inhibitor Veliparib in Combination with Temozolomide in Acute Leukemias

Free
Ivana Gojo, MD, Jan H. Beumer, PharmD, PhD, Keith Pratz, MD, Jiuping Ji, Lihua Wang, PhD, Michelle A. Rudek, PharmD, PhD, Michael A. McDevitt, MD PhD, Maria R. Baer, MD, Amanda Blackford, ScM, B. Douglas Smith, MD, Steven D. Gore, MD, Hetty E. Carraway, MD MBA, Margaret M. Showel, MD, Mark J. Levis, MD PhD, Amy E. DeZern, MD MHS, Douglas Gladstone, MD, Tania Jain, MD, Jackie Greer, RN, Marie Pouquet, PharmD, Ali-walbi Ismail, PharmD, MS, James Herman, MD, Weijie Poh, PhD, Larry Karnitz, PhD, Scott H. Kaufmann, MD PhD, Alice Chen, MD, Judith E Karp, MD
Journal: Blood
Blood (2015) 126 (23): 1361.
https://doi.org/10.1182/blood.V126.23.1361.1361
Published: 2015
Journal Articles

ABT-888 Plus Bendamustine Is Safe and Has Shown Preliminary Efficacy In Patients With Lymphoma

Free
John F. Gerecitano, MD, PhD, Gary K Schwartz, Richard Carvajal, MD, Matthew Fury, MD, PhD, Jason Konner, David M. Hyman, MD, Mrinal Gounder, Devika Gajria, Jerrold Teitcher, Zhigang Zhang, PhD, Craig H. Moskowitz, MD, Jan H Beumer, PharmD, PhD, Alice Chen, MD, Richard F Little, MPH, MD, Fallon France, Juho Whang, Jennifer Winkelman, Megan Stasi, Corey Russell, Naomi Cazeau, Katherine Kargus, Andrew D. Zelenetz, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4366.
https://doi.org/10.1182/blood.V122.21.4366.4366
Published: 2013
Journal Articles

A Novel Sequestosome-1/p62 ZZ Domain Inhibitor Induces New Bone Formation In The Presence Of Myeloma In Vivo

Free
Rebecca Silbermann, MD, Wei Zhao, MBBS, Julie L Eiseman, PhD, Jan H Beumer, PharmD, PhD, Xiang-Qun Xie, PhD, Peng Yang, PhD, Kyaw-Zeyar Myint, PhD, Lirong Wang, PhD, Zhiwei Feng, PhD, Jolene J. Windle, PhD, G. David Roodman, MD, PhD, Noriyoshi Kurihara, DDS, PhD
Journal: Blood
Blood (2013) 122 (21): 684.
https://doi.org/10.1182/blood.V122.21.684.684
Published: 2013
Journal Articles

Pharmacokinetics of Dasatinib in a Patient with Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia During Treatment with Anti-Tuberculosis Therapy

Free
Michelle P. Zeller, MD, Jan H Beumer, Pharm. D., Ph.D., Susan M Christner, B.S., Anargyros Xenocostas, MD, FRCPC
Journal: Blood
Blood (2011) 118 (21): 5006.
https://doi.org/10.1182/blood.V118.21.5006.5006
Published: 2011
Journal Articles

A Phase 1 Open Label, Dose Escalation Study of Nilotinib in Steroid Dependent/Refractory Chronic Graft-Versus-Host Disease

Free
George L. Chen, MD, Paul A. Carpenter, MD, Raewyn Broady, MBChB, FRACP, Tara B. Gregory, MD, Sally Arai, MD, Laura Johnston, MD, Mary E.D. Flowers, MD, Jan H. Beumer, PharmD, PhD, Jodie Mendolsohn, Xin Zhou, Spenser H. Perloff, Joanne M Otani, RN, MSN, David B Miklos, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1986.
https://doi.org/10.1182/blood.V118.21.1986.1986
Published: 2011