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Journal Articles

A phase 1 study of the amino acid modulator pegcrisantaspase and venetoclax for relapsed/refractory acute myeloid leukemia

Clinical Trials & Observations
Yuchen Liu, Dominique R Bollino, Osman M Bah, Erin T Strovel, Tien Van Le, Jinoos Zarrabi, Sunita Philip, Rena G Lapidus, Maria R Baer, Sandrine Niyongere, Vu H. Duong, Christine C Dougherty, Jan Hendrik Beumer, Katherine D Caprinolo, Farin Kamangar, Ashkan Emadi
Journal: Blood
Blood blood.2024024837.
https://doi.org/10.1182/blood.2024024837
Published: 2024
Includes: Supplemental data
Journal Articles

Overcoming Venetoclax (Ven) Resistance through Glutamine (Gln) Depletion: Final Analysis of the Phase 1 Trial of Ven and Pegcrisantaspase (PegC) Combination in Relapsed and Refractory (R/R) Acute Myeloid Leukemia (AML)

Yuchen Liu, Dominique Bollino, Osman M Bah, Erin T Strovel, Jinoos Zarrabi, Sunita Philip, Ezzat Mostafa, Rena G Lapidus, Maria R. Baer, Sandrine Niyongere, Vu H. Duong, Christine C Dougherty, Katherine Caprinolo, Ashkan Emadi
Journal: Blood
Blood (2023) 142 (Supplement 1): 60.
https://doi.org/10.1182/blood-2023-186244
Published: 2023
Journal Articles

Phase I/II Study of Belantamab Mafodotin, Cyclophosphamide, and Dexamethasone (BelCyd) in Relapsed/Refractory Multiple Myeloma

Ashraf Z. Badros, Thea Nash, Christopher Lawrance, Brandon Tittle, Sunita Philip, Sarah Sunshine, Wuqaas Munir, Xiaoxuan Fan, Christina Ide, Djordje Atanackovic
Journal: Blood
Blood (2023) 142 (Supplement 1): 6723.
https://doi.org/10.1182/blood-2023-182254
Published: 2023
Journal Articles

Phase 1 Dose Escalation Trial of Pegcrisantaspase in Combination with Venetoclax in Adults with Relapsed or Refractory Acute Myeloid Leukemia

Dominique R Bollino, Yuchen Liu, Osman Mohamed Bah, Katherine Caprinolo, Jinoos Zarrabi, Sunita Philip, Ezzat Mostafa, Rena G. Lapidus, Zeba Singh, Michael Kallen, Yi Ning, Rima Koka, Maria R. Baer, Sandrine Niyongere, Vu H. Duong, Erin T Strovel, Molly Graveno, Ashkan Emadi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9044–9045.
https://doi.org/10.1182/blood-2022-159621
Published: 2022
Journal Articles

Pegcrisantaspase in Combination with Venetoclax for Treatment of Relapsed or Refractory Acute Myeloid Leukemia: A Phase 1 Study

Sandrine Niyongere, Vu H. Duong, Dominique R Bollino, Rena G. Lapidus, Erin T. Strovel, Jinoos Zarrabi, Osman Mohamed Bah, Sunita Philip, Veronica Kflu, Maria R. Baer, Ashkan Emadi
Journal: Blood
Blood (2021) 138 (Supplement 1): 4433.
https://doi.org/10.1182/blood-2021-150728
Published: 2021
Journal Articles

Pembrolizumab, pomalidomide, and low-dose dexamethasone for relapsed/refractory multiple myeloma

Clinical Trials & Observations
Ashraf Badros, Elizabeth Hyjek, Ning Ma, Alexander Lesokhin, Ahmet Dogan, Aaron P. Rapoport, Mehmet Kocoglu, Emily Lederer, Sunita Philip, Todd Milliron, Cameron Dell, Olga Goloubeva, Zeba Singh
Journal: Blood
Blood (2017) 130 (10): 1189–1197.
https://doi.org/10.1182/blood-2017-03-775122
Published: 2017
Includes: Supplemental data
Journal Articles

Pembrolizumab in Combination with Pomalidomide and Dexamethasone for Relapsed/Refractory Multiple Myeloma (RRMM)

Ashraf Z Badros, MD, Elizabeth Hyjek, MD PhD, Ning Ma, Alexander M. Lesokhin, MD, Aaron P. Rapoport, MD, Mehmet H. Kocoglu, MD, Emily Lederer, RN, Sunita Philip, MBBS, Patricia Lesho, Ashlee Johnson, Cameron Dell, Olga Goloubeva, PhD, Zeba Singh, MD
Journal: Blood
Blood (2016) 128 (22): 490.
https://doi.org/10.1182/blood.V128.22.490.490
Published: 2016
Journal Articles

A Phase II Study of Anti PD-1 Antibody Pembrolizumab, Pomalidomide and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)

Ashraf Z. Badros, MD, Mehmet H. Kocoglu, MD, Ning Ma, NP, Aaron P. Rapoport, MD, Emily Lederer, RN, Sunita Philip, MBBS, Patricia Lesho, Cameron Dell, Nancy M. Hardy, MD, Jean Yared, MD, Olga Goloubeva, PhD, Zeba Singh, MD
Journal: Blood
Blood (2015) 126 (23): 506.
https://doi.org/10.1182/blood.V126.23.506.506
Published: 2015
Journal Articles

Cytokine Alteration In Multiple Myeloma (MM) Patients and Bisphosphonate (BP)-Related Osteonecrosis Of The Jaw (BRONJ)

Ashraf Badros, MD, Sunita Philip, Patricia Lesho, Mariola Sadowska, Dianna Weikel, Timothy Meiller, Rena Lapidus, Lisa Hester, Todd Milliron, Olga Goloubeva
Journal: Blood
Blood (2013) 122 (21): 3153.
https://doi.org/10.1182/blood.V122.21.3153.3153
Published: 2013
Journal Articles

Engineered T-Cells Expressing An HLA-Restricted Affinity-Enhanced TCR In Advanced Multiple Myeloma Patients Post Auto-SCT Engraft and Are Associated With Encouraging Post Auto-SCT Responses

Aaron P. Rapoport, MD, Edward A. Stadtmauer, MD, Dan T. Vogl, MD, MSCE, Brendan M Weiss, MD, Gwendolyn K. Binder-Scholl, PhD, Dominic P. Smethurst, MD, Jeffrey Finklestein, Irina Kulikovskaya, Minnal Gupta, Joanna E. Brewer, PhD, Alan D. Bennett, PhD, Andrew B. Gerry, PhD, Nicholas J. Pumphrey, PhD, Helen K. Tayton-Martin, PhD, Lilliam C. Ribeiro, MBe, Ashraf Badros, MD, Saul Yanovich, MD, Gorgun Akpek, MD, MS, Naseem Kerr, MPH, Sunita Philip, Sandra Westphal, Bruce L. Levine, PhD, Bent K. Jakobsen, PhD, Michael Kalos, PhD, Carl H. June, MD
Journal: Blood
Blood (2013) 122 (21): 766.
https://doi.org/10.1182/blood.V122.21.766.766
Published: 2013
Journal Articles

Combination Immunotherapy After ASCT for Multiple Myeloma (MM) Using MAGE-A3/Poly-ICLC Immunizations Followed by Vaccine-Primed and Activated Autologous T-Cells

Aaron P. Rapoport, MD, Nicole A. Aqui, MD, Edward A. Stadtmauer, MD, Ashraf Z. Badros, MD, Dan T. Vogl, MD, MSCE, YinYan Xu, Brendan M Weiss, MD, Ling Cai, PhD, Hong-Bin Fang, PhD, Elizabeth Veloso, RN, JD, Zhaohui Zheng, MA, Saul Yanovich, MD, Gorgun Akpek, MD, MHS, Sunita Philip, Kathleen Ruehle, RN, Kelly-Marie Betts, MS, Anne Chew, PhD, Holly McConville, RN, BSN, Sandra Westphal, Scott Strome, Andres Salazar, MD, Bruce L. Levine, PhD, Carl H. June, MD
Journal: Blood
Blood (2012) 120 (21): 352.
https://doi.org/10.1182/blood.V120.21.352.352
Published: 2012
Journal Articles

Adoptive Transfer of Gene-Modified T-Cells Engineered to Express High-Affinity TCRs for Cancer-Testis Antigens (CTAs) NY-ESO-1 or Lage-1, in MM Patients Post Auto-SCT

Aaron P. Rapoport, MD, Edward A. Stadtmauer, MD, Dan T. Vogl, MD, MSCE, Brendan M Weiss, MD, Gwendolyn K. Binder-Scholl, PhD, Joanna E. Brewer, PhD, Alan D. Bennett, PhD, Andrew B. Gerry, PhD, Nick J. Pumphrey, PhD, Dominic P. Smethurst, MD, Helen K. Tayton-Martin, PhD, Ribeiro C. Lilliam, MBe, Elizabeth Veloso, JD, BSN, Zhaohui Zheng, MA, Ashraf Z. Badros, MD, Saul Yanovich, MD, Gorgun Akpek, MD, MHS, Holly McConville, RN, BSN, Naseem Kerr, MPH, Sunita Philip, MPH, Kelly-Marie Betts, MS, Sandra Westphal, Michael Kalos, PhD, Bruce L. Levine, PhD, Bent K. Jakobsen, PhD, Carl H. June, MD
Journal: Blood
Blood (2012) 120 (21): 472.
https://doi.org/10.1182/blood.V120.21.472.472
Published: 2012
Journal Articles

Prospective Observational Study of 110 Multiple Myeloma (MM) Patients On Monthly Versus 3 Monthly Infusion of Zoledronic Acid

Ashraf Z. Badros, MD, Sunita Philip, Patricia Lesho, Dianna Weikel, Olga Goloubeva, Mariola Sadowska, Rena Lapidus, PhD, Lisa Hester, Todd Milliron, Timothy Meiller
Journal: Blood
Blood (2012) 120 (21): 4245.
https://doi.org/10.1182/blood.V120.21.4245.4245
Published: 2012
Journal Articles

Prolonged T Cell Persistence, Homing to Marrow and Selective Targeting of Antigen Positive Tumor in Multiple Myeloma Patients Following Adoptive Transfer of T Cells Genetically Engineered to Express an Affinity-Enhanced T Cell Receptor Against the Cancer Testis Antigens NY-ESO-1 and Lage-1

Michael Kalos, PhD, Aaron P. Rapoport, MD, Edward A. Stadtmauer, MD, Dan T. Vogl, MD, Brendan M Weiss, MD, Gwendolyn K. Binder-Scholl, PhD, Dominic P. Smethurst, MD, Irina Kulikovskaya, Minnal Gupta, Timothy L Macatee, Jeffrey M Finklestein, Joanna E. Brewer, PhD, Alan D. Bennett, PhD, Andrew B. Gerry, PhD, Nick J. Pumphrey, PhD, Helen K. Tayton-Martin, PhD, Elizabeth Veloso, JD, BSN, Zhaohui Zheng, MA, Ashraf Z. Badros, MD, Saul Yanovich, MD, Gorgun Akpek, MD, MHS, Holly McConville, RN, BSN, Sunita Philip, Bruce L. Levine, PhD, Bent K. Jakobsen, PhD, Carl H. June, MD
Journal: Blood
Blood (2012) 120 (21): 755.
https://doi.org/10.1182/blood.V120.21.755.755
Published: 2012
Journal Articles

Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination on the basis of hTERT and survivin after ASCT for myeloma

Clinical Trials & Observations
Aaron P. Rapoport, Nicole A. Aqui, Edward A. Stadtmauer, Dan T. Vogl, Hong-Bin Fang, Ling Cai, Stephen Janofsky, Anne Chew, Jan Storek, Gorgun Akpek, Ashraf Badros, Saul Yanovich, Ming T. Tan, Elizabeth Veloso, Marcela F. Pasetti, Alan Cross, Sunita Philip, Heather Murphy, Rita Bhagat, Zhaohui Zheng, Todd Milliron, Julio Cotte, Andrea Cannon, Bruce L. Levine, Robert H. Vonderheide, Carl H. June
Journal: Blood
Blood (2011) 117 (3): 788–797.
https://doi.org/10.1182/blood-2010-08-299396
Published: 2011
Includes: Supplemental data
Journal Articles

Schedule Dependent Effects of Adoptively Transferred Autologous T Cells After AutoSCT for Myeloma: Accelerated Immune Recovery Is Associated with Improved Event-Free Survival.

Aaron P. Rapoport, MD, Nicole A. Aqui, MD, Edward A. Stadtmauer, MD, Dan T. Vogl, MD, Hong-Bin Fang, PhD, Stephen Janofsky, BS, Jan Storek, MD, PhD, Anne Chew, PhD, Elizabeth Veloso, JD, Gorgun Akpek, MD, MS, Saul Yanovich, MD, Ming T. Tan, PhD, Yin Wu, MD, Alan Cross, MD, Sunita Philip, MPH, Heather Murphy, Rita Bhagat, RN, Yiping Liu, Bruce Levine, PhD, Robert H. Vonderheide, MD, DPhil, Carl H. June, MD
Journal: Blood
Blood (2009) 114 (22): 784.
https://doi.org/10.1182/blood.V114.22.784.784
Published: 2009