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Jan Molinsky
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Journal Articles

Role of Angiogenesis and Anti-Angiogenic Treatment Strategies in Mantle Cell Lymphoma

Petra Vockova, MD, Magdalena Klanova, MD PhD, Jan Molinsky, MD PhD, Diana Tuskova, MD, Bokang Calvin Maswabi, MD PhD, Radek Jaksa, MD, Marek Trneny, MD CSc, Pavel Klener, Jr.
Journal: Blood
Blood (2018) 132 (Supplement 1): 1672.
https://doi.org/10.1182/blood-2018-99-116874
Published: 2018
Journal Articles

Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL

Tabea Erdmann, Pavel Klener, James T. Lynch, Michael Grau, Petra Vočková, Jan Molinsky, Diana Tuskova, Kevin Hudson, Urszula M. Polanska, Michael Grondine, Michele Mayo, Beiying Dai, Matthias Pfeifer, Kristian Erdmann, Daniela Schwammbach, Myroslav Zapukhlyak, Annette M. Staiger, German Ott, Wolfgang E. Berdel, Barry R. Davies, Francisco Cruzalegui, Marek Trneny, Peter Lenz, Simon T. Barry, Georg Lenz
Journal: Blood
Blood (2017) 130 (3): 310–322.
https://doi.org/10.1182/blood-2016-12-758599
Published: 2017
Includes: Supplemental data
Journal Articles

B-cell receptor–driven MALT1 activity regulates MYC signaling in mantle cell lymphoma

Beiying Dai, Michael Grau, Mélanie Juilland, Pavel Klener, Elisabeth Höring, Jan Molinsky, Gisela Schimmack, Sietse M. Aukema, Eva Hoster, Niklas Vogt, Annette M. Staiger, Tabea Erdmann, Wendan Xu, Kristian Erdmann, Nicole Dzyuba, Hannelore Madle, Wolfgang E. Berdel, Marek Trneny, Martin Dreyling, Korinna Jöhrens, Peter Lenz, Andreas Rosenwald, Reiner Siebert, Alexandar Tzankov, Wolfram Klapper, Ioannis Anagnostopoulos, Daniel Krappmann, German Ott, Margot Thome, Georg Lenz
Journal: Blood
Blood (2017) 129 (3): 333–346.
https://doi.org/10.1182/blood-2016-05-718775
Published: 2017
Includes: Supplemental data
Journal Articles

B-Cell Receptor Driven MALT1 Activity Regulates MYC Signaling in Mantle Cell Lymphoma

Beiying Dai, Michael Grau, PhD, Mélanie Juilland, PhD, Pavel Klener, MD PhD, Elisabeth Höring, MD, Jan Molinsky, MD PhD, Gisela Schimmack, PhD, Sietse M Aukema, Niklas Vogt, MD, Annette M. Staiger, PhD, Tabea Erdmann, Wendan Xu, Kristian Erdmann, Wolfgang E Berdel, MD, Marek Trneny, MD, Martin H. Dreyling, MD PhD, Korinna Jöhrens, MD, Peter Lenz, PhD, Andreas Rosenwald, MD, Reiner Siebert, Alexandar Tzankov, MD, Wolfram Klapper, MD, Ioannis Anagnostopoulos, MD, Daniel Krappmann, PhD, German Ott, Margot Thome, PhD, Georg Lenz, MD
Journal: Blood
Blood (2016) 128 (22): 611.
https://doi.org/10.1182/blood.V128.22.611.611
Published: 2016
Journal Articles

MCL1 Targeting Agent Homoharringtonine Exerts Strong Cytotoxicity Towards Diffuse Large B-Cell Lymphoma (DLBCL) Cells and Synergizes with BCL2 Targeting Agent ABT199 in Eliminating BCL2-Positive DLBCL Cells

Magdalena Klanova, MD, Ladislav Andera, M.Sc. PhD, Jan Soukup, MDPhD, Brazina Jan, M.Sc., Jan Svadlenka, M.Sc., Simona Benesova, M.Sc., Dana Prukova, M.Sc. PhD, Dana Vejmelkova, M.Sc., Radek Jaksa, MD, Karel Helman, PhD, Petra Vockova, MD, Lucie Lateckova, MD, Jan Molinsky, MD PhD, Bokang Maswabi, MD, Mahmudul Alam, PhD, Roman Kodet, Prof. MD, Marek Trneny, Pavel Klener, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 3645.
https://doi.org/10.1182/blood.V124.21.3645.3645
Published: 2014
Journal Articles

Hematopoietic Stem and Progenitor Cells in Patients with Mature B-Cell Malignancies Are Quantitatively and Qualitatively Deregulated Compared to Healthy Controls

Bokang Maswabi, MD, Dana Prukova, PhD, Jan Molinsky, MD PhD, Magdalena Klanova, MD, Lucie Lateckova, MD, Petra Vockova, MD, Tomas Zikmund, MSc, Filipp Savvulidi, MSc, Mahmudul Alam, PhD, Dana Vejmelkova, PhD, Radek Jaksa, MD, Ludek Sefc, PhD, Martin Vokurka, MD PhD, Marek Trneny, Pavel Klener, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4307.
https://doi.org/10.1182/blood.V124.21.4307.4307
Published: 2014
Journal Articles

Downregulation Of Deoxycytidine Kinase In Cytarabine-Resistant Mantle Cell Lymphoma Cells Confers Cross-Resistance To Nucleoside Analogs Fludarabine, Gemcitabine and Cladribine, But Not To Other Classes Of Anti-Lymphoma Agents

Magdalena Klanova, Lucie Lorkova, MSc, Ondrej Vit, MSc, Bokang Maswabi, MD, Jan Molinsky, MD, Jana Pospisilova, MSc, Cory Mavis, BSc, MSc, Francisco Hernandez, MD, Martin Vokurka, MD, PhD, Jiri Petrak, MSc, PhD, Pavel Klener, Jr., MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3835.
https://doi.org/10.1182/blood.V122.21.3835.3835
Published: 2013
Journal Articles

CD31/PECAM-1 Is Overexpressed On Mantle-Cell Lymphoma (MCL) Primary Cells and Positively Regulates Engraftment and Growth of MCL Cell Lines in Immunodeficient Mice.

Jan Molinsky, MD, Magdalena Klanova, MD, Bokang Maswabi, MD, Josef Karban, MD, Martin Spacek, MD, Marek Trneny, MD, Emanuel Necas, MD, PhD, Jan Zivny, MD, PhD, Pavel Klener, Jr., MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2681.
https://doi.org/10.1182/blood.V120.21.2681.2681
Published: 2012
Journal Articles

Mouse Models of Human Mantle Cell Lymphoma for the Study of Disease Biology and for Pre-Clinical Assessment of Experimental Treatment Approaches.

Pavel Klener, Jr., MD, PhD, Magdalena Klanova, MD, Tomas Soukup, MD, Jan Molinsky, MD, Jan Zivny, MD, PhD, Marek Trneny, MD, Francisco J. Hernandez-Ilizaliturri, MD, Myron S. Czuczman, MD, Emanuel Necas, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2759.
https://doi.org/10.1182/blood.V120.21.2759.2759
Published: 2012
Journal Articles

Roscovitine Sensitizes Leukemia and Lymphoma Cells to TRAIL-Induced Apoptosis and Enhances Cell-Mediated Cytotoxicity

Jan Molinsky, Marie Markova, Magdalena Klanova, Michal Koc, Lenka Beranova, Ladislav Andera, Zdenka Ludvikova, Martina Bohmova, Zdenka Gasova, Marek Trneny, Emanuel Necas, Jan Zivny, Pavel Klener
Journal: Blood
Blood (2010) 116 (21): 596.
https://doi.org/10.1182/blood.V116.21.596.596
Published: 2010
Journal Articles

Upregulation of Caspase 10 Contributes to Acquired Resistance of Acute T-Lymphoblastic Leukemia Cells to Proapoptotic Cytokine TRAIL.

Pavel Klener, Jr., Jan Molinsky, Marie Markova, Sergiu Leahomschi, Tereza Simonova, Ladislav Andera, Emanuel Necas, Jan Zivny
Journal: Blood
Blood (2009) 114 (22): 3790.
https://doi.org/10.1182/blood.V114.22.3790.3790
Published: 2009
Journal Articles

Acquired Resistance to Tumor Necrosis Factor-Related Apoptosis- Inducing Ligand (TRAIL): Histone Deacetylase Inhibitors Resensitize TRAIL-Resistant Jurkat Acute Lymphocytic Leukemia Cells

Pavel Klener, Jr., Jan Molinsky, Tereza Simonova, Emanuel Necas, Ladislav Andera, Jan Zivny
Journal: Blood
Blood (2008) 112 (11): 5032.
https://doi.org/10.1182/blood.V112.11.5032.5032
Published: 2008