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Jay Degen
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Journal Articles

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis

Lurong Lian, Yanfeng Wang, Matthew Flick, John Choi, Edward W. Scott, Jay Degen, Mark A. Lemmon, Charles S. Abrams
Journal: Blood
Blood (2009) 113 (15): 3577–3584.
https://doi.org/10.1182/blood-2008-09-178913
Published: 2009
Journal Articles

Loss of Clotting Function in Mice Expressing a Mutant Form of Fibrinogen Lacking the α Chain Thrombin Cleavage Site

Matthew Flick, PhD, Joni M. Ullman, Joseph S. Palumbo, MD, Eric S. Mullins, MD, Keith W Kombrink, Kathryn E. Talmage, Maureen A. Shaw, Susan T. Lord, Ph.D., Jay Degen, Oleg V Gorkun
Journal: Blood
Blood (2008) 112 (11): 394.
https://doi.org/10.1182/blood.V112.11.394.394
Published: 2008
Journal Articles

Genetic Elimination of Prothrombin in Adult Mice Results in Fatal Spontaneous Hemorrhage in the Heart and Central Nervous System

Eric S. Mullins, MD, Keith W. Kombrinck, Kathryn E. Talmage, Maureen A. Shaw, David P. Witte, Joni M. Ullman, Sandra J. Degen, William Sun, Matthew Flick, PhD, Jay Degen
Journal: Blood
Blood (2008) 112 (11): 395.
https://doi.org/10.1182/blood.V112.11.395.395
Published: 2008
Journal Articles

Mice Lacking Pleckstrin or Pleckstrin-2 Each Have Unique Platelet Secretion Defects.

Yanfeng Wang, M.D., Lurong Lian, M.D., Matthew Flick, Ph.D., Jay Degen, Ph.D., Mark Lemmon, Ph.D., Charles S. Abrams, MD
Journal: Blood
Blood (2007) 110 (11): 134.
https://doi.org/10.1182/blood.V110.11.134.134
Published: 2007
Journal Articles

Knockout of the PKC Substrate Pleckstrin Causes Pleomorphic Defects in Platelets, Lymphocytes and Granulocytes.

Lurong Lian, MD, Yanfeng Wang, M.D., Xinsheng Chen, Ph.D., Tami Bach, M.D., Ph.D., Laurie Lenox, Ph.D., Peimin Zhu, Ph.D., Matthew Flick, Ph.D., Edward Scott, Ph.D., Jay Degen, Ph.D., Bruce Freedman, Ph.D., Gary Koretzky, M.D., Ph.D, Mark Lemmon, Ph.D., Charles S. Abrams, M.D.
Journal: Blood
Blood (2006) 108 (11): 394.
https://doi.org/10.1182/blood.V108.11.394.394
Published: 2006