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David P. Witte
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Journal Articles

HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development

Yoshihiro Hayashi, MD PhD, Yue Zhang, MD, Xiaomei Yan, MD PhD, Kwangmin Choi, PhD, Goro Sashida, MD PhD, Yunzhu Dong, Zefeng Xu, MD, Lingyun Wu, MD PhD, Aili Chen, PhD, Xiujuan Sun, MD, Andre Olsson, PhD, Hironori Harada, MD PhD, Lee-Yung Shih, MD, William Tse, MD FACP, James Bridges, PhD, David P Witte, MD, Qianfei Wang, Michael A. Caligiuri, MD, H. Leighton Grimes, PhD, Stephen D. Nimer, MD, Zhijian Xiao, MD, Gang Huang, PhD
Journal: Blood
Blood (2015) 126 (23): 303.
https://doi.org/10.1182/blood.V126.23.303.303
Published: 2015
Journal Articles

Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain

Eric S. Mullins, Keith W. Kombrinck, Kathryn E. Talmage, Maureen A. Shaw, David P. Witte, Joni M. Ullman, Sandra J. Degen, William Sun, Matthew J. Flick, Jay L. Degen
Journal: Blood
Blood (2009) 113 (3): 696–704.
https://doi.org/10.1182/blood-2008-07-169003
Published: 2009
Includes: Supplemental data
Journal Articles

Hemostatic Factors Support Colitis and Colitis-Associated Colon Cancer

Kris A. Steinbrecher, Netanel Horowitz, Maureen A. Shaw, Kelley A. Barney, Matthew J. Flick, Eleana Harmel-Laws, David P. Witte, Elizabeth A. Blevins, Joseph S. Palumbo, MD
Journal: Blood
Blood (2008) 112 (11): 3079.
https://doi.org/10.1182/blood.V112.11.3079.3079
Published: 2008
Journal Articles

Genetic Elimination of Prothrombin in Adult Mice Results in Fatal Spontaneous Hemorrhage in the Heart and Central Nervous System

Eric S. Mullins, MD, Keith W. Kombrinck, Kathryn E. Talmage, Maureen A. Shaw, David P. Witte, Joni M. Ullman, Sandra J. Degen, William Sun, Matthew Flick, PhD, Jay Degen
Journal: Blood
Blood (2008) 112 (11): 395.
https://doi.org/10.1182/blood.V112.11.395.395
Published: 2008
Journal Articles

Fibrin(ogen) Exacerbates Inflammatory Joint Disease Via a Mechanism Linked to Its αMβ2 Binading Motif.

Matthew J. Flick, PhD, Christine M. La Jeunesse, Kathryn E. Talmage, David P. Witte, MD, Joseph Palumbo, MD, Malinda D. Pinkerton, Sherry Thornton, PhD, Jay L. Degen, PhD
Journal: Blood
Blood (2006) 108 (11): 64.
https://doi.org/10.1182/blood.V108.11.64.64
Published: 2006
Journal Articles

Hemostatic Factors Regulate Immune Surveillance and Contribute to the Rapid Clearance of Bacterial Pathogens In Vivo.

Matthew J. Flick, PhD, Xinli Du, PhD, Kathryn E. Talmage, Christine M. LaJeunesse, David P. Witte, MD, Joseph S. Palumbo, MD, Jay L. Degen, PhD
Journal: Blood
Blood (2005) 106 (11): 2132.
https://doi.org/10.1182/blood.V106.11.2132.2132
Published: 2005
Journal Articles

Plasminogen supports tumor growth through a fibrinogen-dependent mechanism linked to vascular patency

Joseph S. Palumbo, Kathryn E. Talmage, Hong Liu, Christine M. La Jeunesse, David P. Witte, Jay L. Degen
Journal: Blood
Blood (2003) 102 (8): 2819–2827.
https://doi.org/10.1182/blood-2003-03-0881
Published: 2003