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Journal Articles

Thrombosis in PNH: largely gone, but not forgotten

Clinical Trials & Observations
Jeff Szer
Journal: Blood
Blood (2024) 144 (2): 125–126.
https://doi.org/10.1182/blood.2024024660
Published: 2024
Journal Articles

C5 inhibition in PNH: still effective and safe

Jeff Szer
Journal: Blood
Blood (2024) 143 (12): 1064–1065.
https://doi.org/10.1182/blood.2023023626
Published: 2024
Journal Articles

Tranexamic Acid to Prevent Bleeding in Patients with Hematologic Malignancies and Severe Thrombocytopenia (TREATT trial). a Randomized Placebo-Controlled Trial

Lise J Estcourt, Zoe K McQuilten, Peter Bardy, Merrole Cole-Sinclair, Graham P. Collins, Philip J Crispin, Jennifer Curnow, Amber Degelia, Claire Dyer, Vanessa Fox, Adam Friebe, Lajos Floro, Effie Grand, Cara Hudson, Gail Jones, Joanne Joseph, Charlotte Kallmeyer, Marina Karakantza, Paul Kerr, Sara Last, Maria Lobo-Clarke, Matthew Lumley, Mary Frances McMullin, Patrick G. Medd, Suzy M Morton, Andrew David Mumford, Maria Mushkbar, Joe Parsons, Gillian Powter, Mallika Sekhar, Richard Soutar, William S. Stevenson, Elango Subramoniapillai, Robyn Sutherland, Jeff Szer, Neil A Waters, Andrew H. Wei, David Alan Westerman, Sarah A Wexler, Erica M. Wood, Simon J Stanworth
Journal: Blood
Blood (2023) 142 (Supplement 1): 702.
https://doi.org/10.1182/blood-2023-180720
Published: 2023
Journal Articles

Sensitive Molecular Detection of JAK2 V617F Is a Predictive Marker of Relapse in Patients with Myelofibrosis after Allogeneic Stem Cell Transplantation

Rithin Nedumannil, Tal Karmi, Piers Blombery, Charlotte Hughes, Jeff Szer, David S. Ritchie, Lynette C.Y. Chee
Journal: Blood
Blood (2023) 142 (Supplement 1): 629.
https://doi.org/10.1182/blood-2023-174666
Published: 2023
Journal Articles

Ravulizumab Effectiveness in the Real World: Evidence from the International PNH Registry

Alexander Roeth, Christopher J. Patriquin, Jeff Szer, Louis Terriou, Ami Patel, Philippe Gustovic, Jun-Ichi Nishimura, Robert A. Brodsky
Journal: Blood
Blood (2023) 142 (Supplement 1): 2722.
https://doi.org/10.1182/blood-2023-189165
Published: 2023
Journal Articles

Efficacy and Safety of Subcutaneous Ravulizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria Who Received Prior Intravenous Eculizumab: 2-Year Follow-up

Caroline I Piatek, Flore Sicre De Fontbrune, Fahri Sahin, Wolfgang Füreder, Sandra Fatima Gualandro, Wilma Barcellini, Masayo Ogawa, Stephan Ortiz, Ayca Ozol-Godfrey, Jeff Szer, Mustafa Yenerel
Journal: Blood
Blood (2023) 142 (Supplement 1): 2713.
https://doi.org/10.1182/blood-2023-190060
Published: 2023
Journal Articles

Prognostic value of blood biomarkers in steroid-refractory or steroid-dependent acute graft-versus-host disease: a REACH2 analysis

Gerard Socié, Dietger Niederwieser, Nikolas von Bubnoff, Mohamad Mohty, Jeff Szer, Reuven Or, James Garrett, Anirudh Prahallad, Celine Wilke, Robert Zeiser
Journal: Blood
Blood (2023) 141 (22): 2771–2779.
https://doi.org/10.1182/blood.2022018579
Published: 2023
Includes: Supplemental data
Journal Articles

Clinical Outcomes of Chronic Myeloid Leukaemia (CML) Patients on Asciminib through the Managed Access Program (MAP) in Australia

Lynette C.Y. Chee, Nora Lee, Andrew Grigg, Melissa Chen, Anthony Schwarer, Jeff Szer, David T Yeung, Timothy Hughes, Naranie Shanmuganathan
Journal: Blood
Blood (2022) 140 (Supplement 1): 6800–6802.
https://doi.org/10.1182/blood-2022-163221
Published: 2022
Journal Articles

Intensive Pegcetacoplan Dosing in the Management of Acute Hemolysis As Part of the 307 Open-Label Extension Study

Morag Griffin, Richard Kelly, Dries Deeren, Yeow Tee Goh, Eric Tse, Kensuke Usuki, Raymond Wong, Regina Horneff, Lisa Tan, Michael Yeh, Jessica Savage, Jeff Szer
Journal: Blood
Blood (2022) 140 (Supplement 1): 2937–2939.
https://doi.org/10.1182/blood-2022-163117
Published: 2022
Journal Articles

An Analysis of the Worldwide Utilization of Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia

Molly Tokaz, Helen Baldomero, Andrew J Cowan, Wael Saber, Hildegard T. Greinix, Mickey Koh, Nicolaus Kröger, Mohamad Mohty, Sebastian Galeano, Shinichiro Okamoto, Naeem A. Chaudhri, Amado J Karduss, Fabio Ciceri, Vergilio Rensi Colturato, Selim Corbacioglu, Alaa M. Elhaddad, Lisa Force, Cristobal Augusto Frutos Ortiz, Andres Gomez-De Leon, Nada Hamad, Nelson Hamerschlak, Naya He, Aloysius YL Ho, Xiao-Jun Huang, Benjamin Jacobs, Heeje Kim, Minako Iida, Leslie E. Lehmann, Régis Peffault de Latour, Mary-Elizabeth M. Percival, Walid Rasheed, Kirk R. Schultz, Adriana Seber, Bor-Sheng Ko, Anderson Simione, Alok Srivastava, Jeff Szer, William A. Wood, Yoshihisa Kodera, Arnon Nagler, John A Snowden, Daniel J. Weisdorf, Jakob R. Passweg, Marcelo C Pasquini, Anna Sureda, Yoshiko Atsuta, Mahmoud Aljurf, Dietger Niederwieser, Martina Perdomo
Journal: Blood
Blood (2022) 140 (Supplement 1): 8146–8149.
https://doi.org/10.1182/blood-2022-158338
Published: 2022
Journal Articles

Long-Term Survival Benefit of Eculizumab Treatment in Patients with Paroxysmal Nocturnal Hemoglobinuria: Data from the International PNH Registry

Louis Terriou, Christopher J. Patriquin, Morag Griffin, Jong Wook Lee, Philippe Gustovic, Ami S. Patel, Jeff Szer
Journal: Blood
Blood (2021) 138 (Supplement 1): 2188.
https://doi.org/10.1182/blood-2021-153560
Published: 2021
Journal Articles

Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor–experienced adult patients with PNH: the 302 study

Clinical Trials & Observations
Austin G. Kulasekararaj, Anita Hill, Scott T. Rottinghaus, Saskia Langemeijer, Richard Wells, F. Ataulfo Gonzalez-Fernandez, Anna Gaya, Jong Wook Lee, Emilio Ojeda Gutierrez, Caroline I. Piatek, Jeff Szer, Antonio Risitano, Shinji Nakao, Eric Bachman, Lori Shafner, Andrew I. Damokosh, Stephan Ortiz, Alexander Röth, Regis Peffault de Latour
Journal: Blood
Blood (2019) 133 (6): 540–549.
https://doi.org/10.1182/blood-2018-09-876805
Published: 2019
Includes: Supplemental data
Journal Articles

Optimization of Dose Regimen for ALXN1210, a Novel Complement C5 Inhibitor, in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH): Results of 2 Phase 1/2 Studies

Alexander Roeth, MD, Scott T. Rottinghaus, MD, Anita Hill, MBChB (Hons), PhD, Jin Seok Kim, MD PhD, Hubert Schrezenmeier, MD, Louis Terriou, MD, Alvaro Urbano-Ispizua, MD, Richard A. Wells, MD DPhil, Jun Ho Jang, MD PhD, Jeff Szer, MB, BS, FRACP, Rasha Aguzzi, MS, Eric Scott Bachman, MD PhD, Andrew I. Damokosh, PhD, Lori Shafner, PhD, Jong-Wook Lee, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3482.
https://doi.org/10.1182/blood.V130.Suppl_1.3482.3482
Published: 2017
Journal Articles

Narrowing the Gap for Hematopoietic Cell Transplantation in the East-Mediterranean/African Region: Comparison with Global HSCT Indications and Trends. A Report on Behalf of the East Mediterranean (EMBMT), African Blood and Marrow Transplantation Group (AFBMT) and Worldwide Network for Blood and Marrow Transplantation (WBMT)

Dietger Niederwieser, MD, Mahmoud Aljurf, MD, Helen Baldomero, Syed Ziauddin A. Zaidi, FRCP,FRCPath,MBBS, Shahrukh K. Hashmi, MDMPH, Ardeshir Ghavamzadeh, MD, Alaa M. Elhaddad, MD PhD, Rose-Marie Hamladji, Parvez Ahmed, FCPS, Lamia Torjemane, Miguel R Abboud, MD, Abdelghani Tbakhi, MD, Maurtada Khamis Al-Khabori, Asma Quessar, MD, Nosa Bazuaye, Mohamed Amine Bekadja, Salman Naseem Adil, FCPS, Omar Fahmy, MD PhD, Mani Ramzi, Ahmad Ibrahim, MD, Lahoucine Mahmal, Amr Nassar, Fazal Hussain, Hassan El Solh, MD, Nour Ben Abdeljelil, Amir Ali Hamidieh, MD, Amal Al-Seraihy, MD, Mohamed Al Huneini, Yoshihisa Kodera, MD, Hildegard T. Greinix, MD, Mary M. Horowitz, MD MS, Daniel J. Weisdorf, MD, Alois Gratwohl, MD, Jakob R. Passweg, MDMS, Jeff Szer, MB, BS, FRACP, Nicolas Novitzky, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3389.
https://doi.org/10.1182/blood.V130.Suppl_1.3389.3389
Published: 2017
Journal Articles

Reduction in Intravenous Infusion Duration of Enzyme Replacement Therapy to Ten Minutes with Velaglucerase Alfa in Adult Patients with Type 1 Gaucher Disease

Ari Zimran, MD, Shoshana Revel-Vilk, MD, Deborah Elstein, PhD, Naama Arbel, Michal Becker-Cohen, MSc, Gaya Chicco, Jeff Szer, MB, BS, FRACP
Journal: Blood
Blood (2017) 130 (Supplement 1): 2101.
https://doi.org/10.1182/blood.V130.Suppl_1.2101.2101
Published: 2017
Journal Articles

Increasing use of allogeneic hematopoietic cell transplantation in patients aged 70 years and older in the United States

Lori Muffly, Marcelo C. Pasquini, Michael Martens, Ruta Brazauskas, Xiaochun Zhu, Kehinde Adekola, Mahmoud Aljurf, Karen K. Ballen, Ashish Bajel, Frederic Baron, Minoo Battiwalla, Amer Beitinjaneh, Jean-Yves Cahn, Mathew Carabasi, Yi-Bin Chen, Saurabh Chhabra, Stefan Ciurea, Edward Copelan, Anita D’Souza, John Edwards, James Foran, Cesar O. Freytes, Henry C. Fung, Robert Peter Gale, Sergio Giralt, Shahrukh K. Hashmi, Gerhard C. Hildebrandt, Vincent Ho, Ann Jakubowski, Hillard Lazarus, Marlise R. Luskin, Rodrigo Martino, Richard Maziarz, Philip McCarthy, Taiga Nishihori, Rebecca Olin, Richard F. Olsson, Attaphol Pawarode, Edward Peres, Andrew R. Rezvani, David Rizzieri, Bipin N. Savani, Harry C. Schouten, Mitchell Sabloff, Matthew Seftel, Sachiko Seo, Mohamed L. Sorror, Jeff Szer, Baldeep M. Wirk, William A. Wood, Andrew Artz
Journal: Blood
Blood (2017) 130 (9): 1156–1164.
https://doi.org/10.1182/blood-2017-03-772368
Published: 2017
Includes: Supplemental data
Journal Articles

A Prospective Randomized Double Blind Phase 3 Clinical Trial of Anti- T Lymphocyte Globulin (ATLG) to Assess Impact on Chronic Graft-Versus-Host Disease (cGVHD) Free Survival in Patients Undergoing HLA Matched Unrelated Myeloablative Hematopoietic Cell Transplantation (HCT)

Robert J. Soiffer, MD, Haesook T. Kim, PhD, Joseph McGuirk, DO, Mitchell E. Horwitz, MD, Laura Johnston, MD, Mrinal M Patnaik, MBBS, Witold Rybka, MD, Andrew Artz, MD, David L Porter, MD, Thomas C. Shea, MD, Michael W Boyer, MD, Richard T. Maziarz, MD, Madan H. Jagasia, MD, Paul J. Shaughnessy, MD, Usama Gergis, MD, Hana Safah, MD, Ran Reshef, MD, John F. DiPersio, MD PhD, Patrick J. Stiff, MD, Madhuri Vusirikala, MD, Jeff Szer, MB, BS, FRACP, Jennifer Holter, MD, James D. Levine, MD, Paul J. Martin, MD, Joseph A. Pidala, MD, Ian D. Lewis, MBBS PhDFRACP FRCPA, Vincent T. Ho, MD, Edwin P. Alyea, MD, Jerome Ritz, MD, Frank Glavin, Peter Westervelt, MD PhD, Yi-Bin Chen, MD
Journal: Blood
Blood (2016) 128 (22): 505.
https://doi.org/10.1182/blood.V128.22.505.505
Published: 2016
Journal Articles

Increased Idarubicin Dosage during Consolidation Therapy for Adult Acute Myeloid Leukemia Improves Leukemia-Free Survival

Bradstock Kenneth, Emma Link, DPhil, Juliana Di Iulio, BAppSc, PhD, Jeff Szer, MB, BS, FRACP, Paula Marlton, MBBS, FRCPA, FRACP, Andrew Wei, MBBS, PhD, Arno Enno, MB,BS,FRCPA, FRACP, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, Ian D. Lewis, MBBS PhDFRACP FRCPA, James D'Rozario, MB BS FRACP, Luke Coyle, MBBS, FRACP, FRCPA, Gavin Cull, MBBS DM FRACP FRCPA, Philip Campbell, MB ChB FRACP FRCPA, Michael Francis Leahy, FRACP, Uwe H Hahn, MDFGCP FRCPA, Paul Cannell, MD, Campbell Tiley, MBBS,FRACP, FRCPA, Raymond M. Lowenthal, MD FRACP, FRCP, John Moore, MBBS, MD FRACP , FRCPA, Kimberly Cartwright, FRACP,MDFRCPA, Ilona Cunningham, John Taper, MBBS FRACP FRCPA, Andrew Grigg, MBBS, MD FRACP, FRCPA, Andrew W. Roberts, MBBS PhD, Warwick John Benson, Mark S Hertzberg, MBBS PhDFRACP FRCPA, Sandra F. Deveridge, MDBSc,FRACP,FRCPA, Philip Arthur Rowlings, FRACP,FRCPA,MBBS,MS, Anthony K. Mills, MBBS, FRACP, FRCPA, Devinder S Gill, MBChB FRCPath MRCP, Peter G Bardy, MBBS, FRACP, FRCPA, Lynda Campbell, John F. Seymour, MD
Journal: Blood
Blood (2016) 128 (22): 338.
https://doi.org/10.1182/blood.V128.22.338.338
Published: 2016
Journal Articles

Immediate, Complete, and Sustained Inhibition of C5 with ALXN1210 Reduces Complement-Mediated Hemolysis in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH): Interim Analysis of a Dose-Escalation Study

Jong-Wook Lee, MD, Eric Scott Bachman, MD PhD, Rasha Aguzzi, MS, Jun Ho Jang, MD PhD, Jin Seok Kim, MD PhD, Scott T. Rottinghaus, MD, Lori Shafner, PhD, Jeff Szer, MB, BS, FRACP
Journal: Blood
Blood (2016) 128 (22): 2428.
https://doi.org/10.1182/blood.V128.22.2428.2428
Published: 2016
Journal Articles

Prognostic Markers in Core-Binding Factor Acute Myeloid Leukaemia

Ashvind A Prabahran, MBBS, Mark Tacey, BSc, Shaun Fleming, MBBS (Hons), FRACP, FRCPA, Danielle Strong, Andrew Wei, MBBS, PhD, Courtney Tate, MBBS, Paula Marlton, MBBS, Joel Wight, MBBS, Andrew Grigg, MBBS, MD FRACP, FRACPA, Annabel Tuckfield, MBBS, FRACP, FRCPA, PhD, Jeff Szer, MB, BS, FRACP, David S. Ritchie, MDPhD, Lynette C.Y. Chee, MBBS, FRACP, FRCPA, PhD
Journal: Blood
Blood (2015) 126 (23): 2599.
https://doi.org/10.1182/blood.V126.23.2599.2599
Published: 2015