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Jennifer M. Speth
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Journal Articles

Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment

Brief Report
Jennifer M. Speth, Jonathan Hoggatt, Pratibha Singh, Louis M. Pelus
Journal: Blood
Blood (2014) 123 (2): 203–207.
https://doi.org/10.1182/blood-2013-07-516336
Published: 2014
Includes: Supplemental data
Journal Articles

Bone Marrow Sinusoidal Integrity Regulates Hematopoietic Stem and Progenitor Cell Trafficking

Pratibha Singh, PhD, Khalid Mohammad, PhD, Jonathan Hoggatt, PhD, Jennifer M. Speth, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2013) 122 (21): 3687.
https://doi.org/10.1182/blood.V122.21.3687.3687
Published: 2013
Journal Articles

Hif1α and Rac1 Are Necessary For Enhanced HSPC Migration and Homing In Response To Prostaglandin E 2 Treatment

Jennifer M. Speth, PhD, Maegan L. Capitano, Ph.D., Jonathan Hoggatt, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2013) 122 (21): 889.
https://doi.org/10.1182/blood.V122.21.889.889
Published: 2013
Journal Articles

Blockade of prostaglandin E 2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells

Pratibha Singh, Jonathan Hoggatt, Peirong Hu, Jennifer M. Speth, Seiji Fukuda, Richard M. Breyer, Louis M. Pelus
Journal: Blood
Blood (2012) 119 (7): 1671–1682.
https://doi.org/10.1182/blood-2011-03-342428
Published: 2012
Includes: Supplemental data
Journal Articles

Enhanced Homing of HSPCs After Treatment with Prostaglandin E2 (PGE 2 ) May Be An Effect of Transcriptional Regulation of CXC Chemokine Receptor 4 (CXCR4) Through Hypoxia Inducible Factor 1α (HIF1α)

Jennifer M Speth, Jonathan Hoggatt, Ph.D., Louis M. Pelus, PhD
Journal: Blood
Blood (2011) 118 (21): 918.
https://doi.org/10.1182/blood.V118.21.918.918
Published: 2011
Journal Articles

Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

Jonathan Hoggatt, Ph.D., Khalid S Mohammad, M.D. Ph.D., Brahmananda Reddy Chitteti, PhD, Pratibha Singh, PhD, Jennifer M Speth, Peirong Hu, PhD, Bradley Poteat, Edward Srour, PhD, Theresa Guise, M.D., Louis M. Pelus, PhD
Journal: Blood
Blood (2011) 118 (21): 724.
https://doi.org/10.1182/blood.V118.21.724.724
Published: 2011
Journal Articles

Cyclooxygenase-2 Derived Prostaglandin E2 Is Required for Dendritic Cell Differentiation From Hematopoietic Progenitor Cells.

Pratibha Singh, PhD, Jonathan Hoggatt, MS, Jennifer M. Speth, MS, Louis M. Pelus, PhD
Journal: Blood
Blood (2009) 114 (22): 1499.
https://doi.org/10.1182/blood.V114.22.1499.1499
Published: 2009
Journal Articles

Inhibition of Prostaglandin E 2 (PGE 2 ) Signaling by Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or EP4 Receptor Antagonism Expands Hematopoietic Stem and Progenitor Cells (HSPC) and Enhances Their Mobilization to Peripheral Blood in Mice and Baboons.

Jonathan Hoggatt, MS, Pratibha Singh, PhD, Amber Hoggatt, D.V.M., Jennifer M. Speth, Louis M. Pelus, PhD
Journal: Blood
Blood (2009) 114 (22): 84.
https://doi.org/10.1182/blood.V114.22.84.84
Published: 2009