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Louis M. Pelus
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Journal Articles

Engraftment and Reconstitution of Hematopoiesis Is Dependent on Endothelial Cell Expressed Prostaglandin EP4 Receptor Signaling Mediated Regeneration of Vascular Niche

Pratibha Singh, PhD, Hongge Li, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1293.
https://doi.org/10.1182/blood-2018-99-119723
Published: 2018
Journal Articles

Prostaglandin E2 Promotes Recovery of Thymus in Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS)

TONG WU, MD PhD, Artur Plett, PhD, Hui Lin Chua, PhD, Louis M. Pelus, PhD, Christie M. Orschell, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1008.
https://doi.org/10.1182/blood.V130.Suppl_1.1008.1008
Published: 2017
Journal Articles

Prostaglandin E2 Protects HSC from DNA Damage Induced By Ionizing Radiation By Preventing Generation of Reactive Oxygen Species and Histone Acetylation

Liqiong Liu, MD PhD, Andrea M Patterson, PhD, Hui Lin Chua, PhD, Carol Sampson, MS, Artur Plett, PhD, Hongge Li, PhD, Pratibha Singh, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1151.
https://doi.org/10.1182/blood.V130.Suppl_1.1151.1151
Published: 2017
Journal Articles

Prostaglandin E 2 Prevents Apoptosis and Promotes Homeostasis of Hematopoietic Stem Cells after Lethal Irradiation through Alteration of p53 and TNF Signaling

Andrea M Patterson, PhD, Liqiong Liu, MD PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3766.
https://doi.org/10.1182/blood.V130.Suppl_1.3766.3766
Published: 2017
Journal Articles

Attenuation of CXCR4/SDF-1 Axis in Bone Marrow Mesenchymal Stromal Cells Impairs Hematopoietic Niche Activity and Promotes Stem Cell Aging

Pratibha Singh, PhD, Melissa A Kacena, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 92.
https://doi.org/10.1182/blood.V130.Suppl_1.92.92
Published: 2017
Journal Articles

Prostaglandin E 2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation

Andrea M. Patterson, PhD, Pratibha Singh, PhD, Hongge Li, PhD, Hui Lin Chua, PhD, Alexa Fisher, BS, Carol Sampson, MS, Artur Plett, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2016) 128 (22): 1481.
https://doi.org/10.1182/blood.V128.22.1481.1481
Published: 2016
Journal Articles

Neuropeptide Y Is Critical for Bone Marrow Stromal Cells and Hematopoietic Recovery Following Injury

Pratibha Singh, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2016) 128 (22): 173.
https://doi.org/10.1182/blood.V128.22.173.173
Published: 2016
Journal Articles

CXCR4-SDF-1 Signaling in Nestin+ Mesenchymal Stem Cell Is Required for HSC Maintenance during Homeostasis and Regeneration after Irradiation

Pratibha Singh, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2016) 128 (22): 3883.
https://doi.org/10.1182/blood.V128.22.3883.3883
Published: 2016
Journal Articles

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Jonathan Hoggatt, PhD, Pratibha Singh, PhD, Tiffany Tate, BS, Peter V. Kharchenko, PhD, Amir Schajnovitz, PhD, Ninib Barawnyo, PhD, Francois Mercier, MD, Dwight Morrow, PhD, David T. Scadden, MD, Louis M. Pelus, PhD
Journal: Blood
Blood (2016) 128 (22): 368.
https://doi.org/10.1182/blood.V128.22.368.368
Published: 2016
Journal Articles

Prostaglandin E2 Signaling through EP4 Receptor Promotes Hematopoietic Stem Cell Niche Regeneration and Enhances Hematopoietic Recovery

Pratibha Singh, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2015) 126 (23): 784.
https://doi.org/10.1182/blood.V126.23.784.784
Published: 2015
Journal Articles

Mitigation of a Newly Discovered Phenomenon, Extra Physiologic Oxygen Shock/Stress (EPHOSS), Mediated By the Mitochondria Permeability Transition Pore, Greatly Improves Stem Cell Collection and Transplantation

Charlie Mantel, Heather A. O'Leary, PhD, Brahmananda Reddy Chitteti, PhD, Xinxin Huang, PhD, Scott Cooper, BS, Giao Hangoc, DVM, PhD, Nickolay Brustovetsky, PhD, Edward F. Srour, PhD, Man Ryul Lee, PhD, Steven Messina-Graham, Nadia Falah, MD, Reuben Kapur, PhD, Louis M. Pelus, PhD, Mircea Ivan, MD, PhD, Kye-Seong Kim, PhD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2014) 124 (21): 2905.
https://doi.org/10.1182/blood.V124.21.2905.2905
Published: 2014
Journal Articles

Survivin Is a Master Regulator of Mesenchymal Stem Cell Functions and Potential Therapeutic Target for Mesenchymal Stem Cell Expansion

Pratibha Singh, PhD, Seiji Fukuda, MD PhD, Mary R. Saunders, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2014) 124 (21): 774.
https://doi.org/10.1182/blood.V124.21.774.774
Published: 2014
Journal Articles

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

Brahmananda Reddy Chitteti, Michihiro Kobayashi, Yinghua Cheng, Huajia Zhang, Bradley A. Poteat, Hal E. Broxmeyer, Louis M. Pelus, Helmut Hanenberg, Amy Zollman, Malgorzata M. Kamocka, Nadia Carlesso, Angelo A. Cardoso, Melissa A. Kacena, Edward F. Srour
Journal: Blood
Blood (2014) 124 (4): 519–529.
https://doi.org/10.1182/blood-2014-03-565721
Published: 2014
Includes: Supplemental data
Journal Articles

Delta-1 provides pleasant stem cell environs

Louis M. Pelus, Pratibha Singh
Journal: Blood
Blood (2014) 123 (5): 605–606.
https://doi.org/10.1182/blood-2013-12-539841
Published: 2014
Journal Articles

Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment

Brief Report
Jennifer M. Speth, Jonathan Hoggatt, Pratibha Singh, Louis M. Pelus
Journal: Blood
Blood (2014) 123 (2): 203–207.
https://doi.org/10.1182/blood-2013-07-516336
Published: 2014
Includes: Supplemental data
Journal Articles

Bone Marrow Sinusoidal Integrity Regulates Hematopoietic Stem and Progenitor Cell Trafficking

Pratibha Singh, PhD, Khalid Mohammad, PhD, Jonathan Hoggatt, PhD, Jennifer M. Speth, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2013) 122 (21): 3687.
https://doi.org/10.1182/blood.V122.21.3687.3687
Published: 2013
Journal Articles

Hif1α and Rac1 Are Necessary For Enhanced HSPC Migration and Homing In Response To Prostaglandin E 2 Treatment

Jennifer M. Speth, PhD, Maegan L. Capitano, Ph.D., Jonathan Hoggatt, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2013) 122 (21): 889.
https://doi.org/10.1182/blood.V122.21.889.889
Published: 2013
Journal Articles

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

Clinical Trials & Observations
Corey Cutler, Pratik Multani, David Robbins, Haesook T. Kim, Thuy Le, Jonathan Hoggatt, Louis M. Pelus, Caroline Desponts, Yi-Bin Chen, Betsy Rezner, Philippe Armand, John Koreth, Brett Glotzbecker, Vincent T. Ho, Edwin Alyea, Marlisa Isom, Grace Kao, Myriam Armant, Leslie Silberstein, Peirong Hu, Robert J. Soiffer, David T. Scadden, Jerome Ritz, Wolfram Goessling, Trista E. North, John Mendlein, Karen Ballen, Leonard I. Zon, Joseph H. Antin, Daniel D. Shoemaker
Journal: Blood
Blood (2013) 122 (17): 3074–3081.
https://doi.org/10.1182/blood-2013-05-503177
Published: 2013
Includes: Supplemental data
Journal Articles

Prostaglandin E 2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness

Brief Report
Jonathan Hoggatt, Khalid S. Mohammad, Pratibha Singh, Louis M. Pelus
Journal: Blood
Blood (2013) 122 (17): 2997–3000.
https://doi.org/10.1182/blood-2013-07-515288
Published: 2013
Journal Articles

The Internal-Tandem-Duplication of Flt3 Mutation Generates Growth Inhibitory Signals in Mouse Hematopoietic Progenitor Cells by Down-Regulating Pbx1 Expression Via P21 cdkn1a .

Seiji Fukuda, MD, PhD, Mariko Abe, MD, Tomohiro Hirade, MD, Chie Onishi, MD, Louis M. Pelus, PhD, Seiji Yamaguchi, MD
Journal: Blood
Blood (2012) 120 (21): 2340.
https://doi.org/10.1182/blood.V120.21.2340.2340
Published: 2012