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Jessica M Wagner
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Journal Articles

Single Agent and Combinatorial Efficacy of First-in-Class Small Molecule ONC201 in Acute Leukemia and Multiple Myeloma

Varun V Prabhu, PhD, Amriti Lulla, Christina L Kline, PhD, Peter J Van den Heuvel, PhD, Mala K. Talekar, MD, Jessica M Wagner, Rohinton S Tarapore, PhD, David T Dicker, Mathew J Garnett, PhD, Ultan McDermott, MD PhD, Cyril H Benes, PhD, Jeffrey J. Pu, MD PhD, David F. Claxton, MD, Wolfgang Oster, MD PhD, Joshua E Allen, PhD, Wafik S. El-Deiry, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2759.
https://doi.org/10.1182/blood.V128.22.2759.2759
Published: 2016
Journal Articles

Potent Anti-Leukemic Effects of Small Molecule ONC212, a Member of the Imipridone Class of Anti-Cancer Compounds

Varun V Prabhu, PhD, Rohinton S Tarapore, PhD, Mathew J Garnett, PhD, Ultan McDermott, MD PhD, Cyril H Benes, PhD, Jessica M Wagner, Wafik S. El-Deiry, MD PhD, Martin Stogniew, PhD, Wolfgang Oster, MD PhD, Joshua E Allen, PhD
Journal: Blood
Blood (2016) 128 (22): 5133.
https://doi.org/10.1182/blood.V128.22.5133.5133
Published: 2016
Journal Articles

Caspase-Dependent Anti-Tumor Effects of ONC201/TIC10 on Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Amriti R. Lulla, Christina Leah B Kline, PhD, Liz J. Hernandez-Borrero, Varun Vijay Prabhu, Jessica M Wagner, David T. Dicker, Nathan G. Dolloff, PhD, Brian M Barth, PhD, Jeffrey J Pu, MD PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP
Journal: Blood
Blood (2014) 124 (21): 5224.
https://doi.org/10.1182/blood.V124.21.5224.5224
Published: 2014
Journal Articles

Screen of Small Molecule ONC201/TIC10 Identifies Single Agent Activity and Combinatorial Efficacy with Bortezomib, Rituximab or Dexamethasone in Killing of Acute Lymphoblastic Leukemia Cells

Jessica M Wagner, Varun Vijay Prabhu, Leah L. Kline, PhD, Amriti R. Lulla, Liz J. Hernandez-Borrero, Jeffrey J. Pu, MD PhD, David T. Dicker, Brian M Barth, PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP
Journal: Blood
Blood (2014) 124 (21): 5233.
https://doi.org/10.1182/blood.V124.21.5233.5233
Published: 2014
Journal Articles

Small Molecule ONC201/TIC10 Induces Caspase-Dependent Apoptosis in Acute Lymphoblastic Leukemia Cells Via Modulation of Bcl-2 and IAP Family Proteins

Varun Vijay Prabhu, Amriti R. Lulla, Jessica M Wagner, Liz J. Hernandez-Borrero, Mala K. Talekar, MD, Christina L. Kline, PhD, David T. Dicker, Brian M Barth, PhD, Jeffrey J. Pu, MD PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP
Journal: Blood
Blood (2014) 124 (21): 5237.
https://doi.org/10.1182/blood.V124.21.5237.5237
Published: 2014