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Journal Articles

Efficacy and safety of gecacitinib in thrombocytopenic myelofibrosis patients

Free
Yi Zhang, Hu Zhou, Junling Zhuang, Zhongxing Jiang, Dengshu Wu, Qingchi Liu, Huanling Zhu, Qike Zhang, Xin Du, Sujun Gao, Qian Jiang, Wei Li, Linhua Yang, Yuqing Chen, Aili He, Jinwen Huang, Yan Li, Xiuli Wang, Guangsheng He, Hongmei Jing, Zhijian Xiao, Minghui Duan, Mei Hong, Fei Li, Yarong Li, Liangming Ma, Jishi Wang, Wei WANG, Wen Wu, Na Xu, Feng Zhang, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2028.
https://doi.org/10.1182/blood-2025-2028
Published: 2025
Journal Articles

Burden of Hodgkin lymphoma from 1990 to 2021 and modelled projection to 2050

Free
weili wang, shensui li, Jishi Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 1848.
https://doi.org/10.1182/blood-2025-1848
Published: 2025
Journal Articles

The core role of exosomal mir-21-5p/TGF-β1-CXCL12/RANKL axis in bone marrow microenvironment remodeling in multiple myeloma and targeted intervention strategies

Free
Li Wang, Aoshuang Huang, Jishi Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 2167.
https://doi.org/10.1182/blood-2025-2167
Published: 2025
Journal Articles

Rhoifolin, an inhibitor targeting the ALDH2-PKC delta axis, eradicates MRD in chronic myeloid leukemia by eliminating leukemia stem cells

Free
Xiuying Hu, Jishi Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 7847.
https://doi.org/10.1182/blood-2025-7847
Published: 2025
Journal Articles

Heme oxygenase-1 facilitates immune evasion in diffuse large B-cell lymphoma by reprogramming tumor-associated macrophage polarization

Free
Wenbin Lei, Jishi Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 5085.
https://doi.org/10.1182/blood-2025-5085
Published: 2025
Journal Articles

Mechanistic study of the Cullin3-CRL3^KEAP1-NRF2 neddylation axis in chemotherapy resistance of Acute Myeloid Leukemia stem cells

Free
Li Wang, Aoshuang Huang, Jishi Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 5065.
https://doi.org/10.1182/blood-2025-5065
Published: 2025
Journal Articles

A first-in-human, phase I/II, open-label, multicenter, dose escalation and expansion study of lbl-034, a conditionally activated bispecific antibody targeting GPRC5D and CD3 with a 2:1 format, in patients with relapsed/refractory multiple myeloma

Free
Xuelin Dou, Yuping Zhong, Wanhong Zhao, Ling Qin, Xin Du, Aijun Liao, Zhongjun Xia, Chunyan Sun, Songfu Jiang, Dongping Huang, Haitang Xie, Liangming Ma, Jishi Wang, Fengyan Jin, Guifang Ouyang, Yanhong Tong, Min Dong, Bing Xu, Wenduo He, Shengli Cai, Jin Lu
Journal: Blood
Blood (2025) 146 (Supplement 1): 91.
https://doi.org/10.1182/blood-2025-91
Published: 2025
Journal Articles

Results of a registrational Phase 2 study of lisaftoclax monotherapy for treatment of patients (pts) with Relapsed/Refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) who had failed Bruton's tyrosine kinase inhibitors (BTKis)

Free
Keshu Zhou, Tingyu Wang, Ting Niu, Meifang Zheng, Jie Jin, Yang Liang, Rui Huang, Shuangnian Xu, Jianhua Qu, Guohui Cui, Fei Li, Yiming Luo, Ru Feng, Wenzheng Yu, Caixia Li, Zhiling Yan, Xin Zhou, Suijing Wu, Lihong Liu, Yinghua Geng, Jishi Wang, Sujun Gao, Jianfei Fu, Xiaoping Zhang, Chunyan Ji, Qianqian Xiang, Xiongpeng Zhu, Yajing Xu, Li'e Lin, Xiaoyu Zhu, Yuping Zhong, Hongling Peng, Ying Zhao, Hui Zeng, Zhao Wang, Rong Fu, Wenbin Qian, Yingmin Liang, Xiaobing Huang, Yajun Li, Min Yu, Zi Chen, Lei Wang, Lichuang Men, Zhiyan Liang, Shan Zeng, Baoer Lu, Yifan Zhai, Jianyong Li
Journal: Blood
Blood (2025) 146 (Supplement 1): 88.
https://doi.org/10.1182/blood-2025-88
Published: 2025
Journal Articles

Targeting DCAF5 restores p53 tumor suppressor function and exerts anti-leukemic effects in AML

Free
Ping Wang, Jishi Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 5011.
https://doi.org/10.1182/blood-2025-5011
Published: 2025
Journal Articles

NRF2 transcriptionally activates DDIT4 to drive venetoclax resistance in AML

Free
shuyun cao, Jishi Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 6820.
https://doi.org/10.1182/blood-2025-6820
Published: 2025
Journal Articles

Long-term treatment continuation of gecacitinib in myelofibrosis patients after ruxolitinib failure

Free
Yi Zhang, Hu Zhou, Qike Zhang, Qingchi Liu, Sujun Gao, Zhijian Xiao, Minghui Duan, Liangming Ma, Wei WANG, Huibing Dang, Guangsheng He, Hongmei Jing, Junmin Li, Haiping Yang, Huanling Zhu, Chunkang Chang, Yuqing Chen, Xin Du, Mei Hong, Xin Li, Jishi Wang, Na Xu, Peng Zhao, Shanshan Suo, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 5584.
https://doi.org/10.1182/blood-2025-5584
Published: 2025
Journal Articles

Post Hoc Analysis of Phase III Gecacitinib Clinical Trial Outcomes: Enhanced Understanding and Implications

Free
Yi Zhang, Hu Zhou, Shanshan Suo, Junling Zhuang, Linhua Yang, Aili He, Qingchi Liu, Xin Du, Sujun Gao, Yarong Li, Yan Li, Yuqing Chen, Wen Wu, Huanling Zhu, Guangsheng He, Mei Hong, Qian Jiang, Zhongxing Jiang, Hongmei Jing, Jishi Wang, Na Xu, Lingling Yue, Cuiping Zheng, ZePing Zhou, Chenghao Jin, Xin Li, Lin Liu, Yajing Xu, Dengshu Wu, Feng Zhang, Jin Zhang, Zhijian Xiao, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3165.
https://doi.org/10.1182/blood-2024-202790
Published: 2024
Journal Articles

High Expression Level of MMP7 and Mir-489-3p/MMP7 Axis Associates with Venetoclax Resistance in Acute Myelogenous Leukemia

Free
Li Wang, Jishi Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5768.
https://doi.org/10.1182/blood-2023-186242
Published: 2023
Journal Articles

Overexpression of Nrf2 in Mesenchymal Stem Cells Promotes Migration and Invasion of B- Acute Lymphoblastic Leukemia Cells

Free
Lin Zheng, Chengyun Pan, Qin Shang, Tianzhen Hu, Shuyun Cao, Li Wang, Hong Luo, Weili Wang, Jishi Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5622.
https://doi.org/10.1182/blood-2023-185784
Published: 2023
Journal Articles

Efficacy and Safety of Clifutinib, a Novel, Highly Selective, Oral FLT3 Inhibitor, in Patients with FLT3-Mutated Relapsed or Refractory Acute Myeloid Leukemia：Updated Results from a Phase I Study

Free
Jie Jin, Huafeng Wang, Wen-Juan Yu, Zheng Ge, Xudong Wei, Yuhua Li, Zhongxing Jiang, Yiqing Li, Xin Du, Linhua Yang, Lie Lin, Jishi Wang, Yazhou Yao, Xiaoping Hu, Jianping Lan, Xiuzhi Deng, Tong Chen, Xianqi Feng, Dengju Li, Ming Hou, Rong Fu, Siyong Huang, Jingbo Wang, Xin Du, Hui Yang, Haiping Yang, Yingzhi Jiang, Zhijie Wang, Deng Li, Bing Liu, Ning Kang, Yulei Zhuang, Yingjun Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4281.
https://doi.org/10.1182/blood-2023-188961
Published: 2023
Journal Articles

BRG1 Regulates Adult B-Cell Acute Lymphoblastic Leukemia Proliferation and Apoptosis By Interacting with c-MYC and Activating PI3K/AKT Pathway

Free
Qian Kang, Peng Zhao, Ming Ni, Qin Fang, Jishi Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5725.
https://doi.org/10.1182/blood-2023-185319
Published: 2023
Journal Articles

CD56briCD27+CD11b+/- NK Cells Mediated Remission of Agvhd Via Immunoregulation

Free
Ming Ni, Peng Zhao, Qian Kang, Chengyun Pan, Xiuying Hu, Tianzhen Hu, Qin Fang, Jishi Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 7011.
https://doi.org/10.1182/blood-2023-185534
Published: 2023
Journal Articles

Study on the Synthetic Lethal Mechanism of Selective Killing of ALDH2 Deficient Acute Myeloid Leukemia Cells By Inhibiting BRIP1

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Jishi Wang, Xiuying Hu
Journal: Blood
Blood (2023) 142 (Supplement 1): 7142.
https://doi.org/10.1182/blood-2023-188050
Published: 2023
Journal Articles

Updated Efficacy and Safety Results of Lisaftoclax (APG-2575) in Patients (Pts) with Heavily Pretreated Chronic Lymphocytic Leukemia (CLL): Pooled Analyses of Two Clinical Trials

Free
Keshu Zhou, Mingyuan Sun, Xu Wei, Shuhua Yi, Junyuan Qi, Weiqi Nian, Guohui Cui, Jishi Wang, Xiaoping Zhang, Hong Cen, Fuling Zhou, Jianying Huang, Huilan Liu, Aizong Shen, Liangquan Geng, Ru Feng, Chongyuan Xu, Wenbin Qian, Fei Li, Lihong Liu, Caixia Li, Xielan Zhao, Jie Jin, Hongmei Jing, Dongmei Ji, Fangfang Lyu, Zi Chen, Lichuang Men, Hengbang Wang, Ke Zhang, Liang Xu, Zhang Zhang, Dajun Yang, Jianxiang Wang, Jianyong Li, Yifan Zhai
Journal: Blood
Blood (2023) 142 (Supplement 1): 1900.
https://doi.org/10.1182/blood-2023-183071
Published: 2023
Journal Articles

RAB22A As a Predictor of Exosome Secretion in the Progression and Relapse of Multiple Myeloma

Free
Bingjie Fan, Jishi Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3338.
https://doi.org/10.1182/blood-2023-185357
Published: 2023