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Journal Articles

Heightened Endoplasmic-Reticulum Stress Is a Targetable Vulnerability of Malignant Plasma Cells in Multiple Myeloma

Danai Dima, Metis Hasipek, Divya Jyoti Singh, Dongxu Jiang, Anand D. Tiwari, Dale Grabowski, Yvonne Parker, Daniel J. Lindner, Jianjun Zhao, Kenneth H. Shain, Jack Khouri, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2022) 140 (Supplement 1): 7100–7101.

https://doi.org/10.1182/blood-2022-169516

Published: 2022

Journal Articles

A Single Gene-Mediated Perturbation of the Human Genome Leads to Malignant Transformation in a Murine Transgenic Model

Jianhong Lin, MD MSc, Chun Yang, MD PhD, Li Xue, MD PhD, Zhenkui Wang, MD PhD, Yan Xu, MD, Mehmet Kemal Samur, PhD, Jianjun Zhao, MD, Ariel Kwart, BS, Masood A. Shammas, PhD, Xiaofeng Jiang, MD PhD, Wong Kwok-Kin, MD PhD, Ruben D. Carrasco, MD PhD, Kenneth C Anderson, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4410.

https://doi.org/10.1182/blood.V130.Suppl_1.4410.4410

Published: 2017

Journal Articles

Modeling Lymphoplasmacytic Lymphoma/Waldenström Macroglobulinemia in Transgenic Mice Using Human MYD88 L256P Mutated Protein

Tomasz Sewastianik, MSc,PhD, Maria Luisa Guerrera, MD, Meng Jiang, MD, Peter S. Dennis, Jianjun Zhao, MD, Guang Yang, PhD, Zachary Hunter, PhD, Geraldine S. Pinkus, Petr Jarolim, MD PhD, Wong Kwok-Kin, MD PhD, Steven P Treon, MDPhDFRCP, Ruben D. Carrasco, MD PhD

Blood (2017) 130 (Supplement 1): 2510.

https://doi.org/10.1182/blood.V130.Suppl_1.2510.2510

Published: 2017

Journal Articles

Targeting the MALAT1/PARP1/LIG3 Complex Induces DNA Damage and Apoptosis in Multiple Myeloma Mouse Models

Yi Hu, Jing Fang, Hua Fang, Chen Li, Shuang Liu, Sarah L. Ondrejka, MD, Zihua Gong, Jaroslaw P. Maciejewski, PhD MD FACP, Frederic J. Reu, MD, Qing Yi, MD PhD, Jianjun Zhao, MD

Blood (2017) 130 (Supplement 1): 1829.

https://doi.org/10.1182/blood.V130.Suppl_1.1829.1829

Published: 2017

Journal Articles

Germinal Center-Derived Lymphomas and Plasmacytomas in Mice with Targeted Deletion of MiR-15a/16-1 in Activated B Cells

Tomasz Sewastianik, PhD, Jianjun Zhao, MD PhD, Meng Jiang, MD, Jianli Wang, MD PhD, Vinodh Pillai, MD PhD, Peter S. Dennis, BS, Jianhong Lin, MD M.Sc, Daniel Brooks, Mary Bouxsein, PhD, Geraldine S Pinkus, MD, Petr Jarolim, MD PhD, Davide Robbiani, Irene M. Ghobrial, MD, Kenneth C. Anderson, MD, Ruben D. Carrasco, MD PhD

Blood (2016) 128 (22): 743.

https://doi.org/10.1182/blood.V128.22.743.743

Published: 2016

Journal Articles

Overexpression of BCL9, a Wnt/β-Catenin Transcriptional Co-Activator, in Transgenic Mice Promotes Spontaneous Development of B-Cell Malignancies

Tomasz Sewastianik, PhD, Jianjun Zhao, MD PhD, Meng Jiang, MD, Peter S. Dennis, BS, Myles Brown, MD, Kwok Wong, MD, Ruben D. Carrasco, MD PhD

Blood (2016) 128 (22): 441.

https://doi.org/10.1182/blood.V128.22.441.441

Published: 2016

Journal Articles

Apurinic/Apyrimidinic Endonuclease 1 Induced Genomic Instability Causes T-Cell Acute Lymphoblastic Leukemia in Zebrafish

Jianhong Lin, MD M.Sc, Chun Yang, MD PhD, Ariel Kwart, B.S., Jianjun Zhao, MD PhD, Mehmet K Samur, PhD, Weihong Zhang, MD, Purushothama Nanjappa, M.S., Teresa Calimeri, MD PhD, Xiubao Ren, MD, Dongdong Ma, MD PhD, Xiaofeng Jiang, MD PhD, Yi Zhou, PhD, Masood Shammas, PhD, Kenneth C. Anderson, MD, Jon C. Aster, MD PhD, Leonard I. Zon, MD, Robert I. Handin, MD, Nikhil C. Munshi, MD

Blood (2015) 126 (23): 1431.

https://doi.org/10.1182/blood.V126.23.1431.1431

Published: 2015

Journal Articles

Blocking Specific CD44 Splicing Variant Isoform Inhibits the Differentiation of Th-2 Cells through Interfering with IL-4/IL-4R Signaling Pathway

Chun Yang, MD PhD, Jianhong Lin, MD M.Sc, Hongyan Liang, MD PhD, Ariel Kwart, B.S., Meng Jiang, MD, Jianjun Zhao, MD PhD, Xiaofeng Jiang, MD PhD, Nikhil C. Munshi, MD

Blood (2015) 126 (23): 285.

https://doi.org/10.1182/blood.V126.23.285.285

Published: 2015

Journal Articles

Follicular Dendritic Cell (FDC)-Induced Microrna-Mediated up-Regulation of PRDM1 and Down-Regulation of BCL6 in Germinal Center B Lymphocytes: A Potential Mechanism for B-Cell Differentiation.

Jianhong Lin, MD, Tint Lwin, MD, PhD, Jianjun Zhao, MD, Jie Zhao, MD, Luis Crespo, BS, Eduardo M. Sotomayor, MD, Lynn C. Moscinski, MD, William S. Dalton, PhD, MD, Ken Wright, PhD, Jianguo Tao, MD, PhD

Blood (2009) 114 (22): 4588.

https://doi.org/10.1182/blood.V114.22.4588.4588

Published: 2009

Journal Articles

MiR-29 MicroRNAs Regulate IGF-1R Expression and Contribute Mantle Cell Lymphoma Growth and Survival.

Jianhong Lin, MD, Jianjun Zhao, MD, Tint Lwin, MD, PhD, Crespo Luis, BS, Fangxia Guan, MD, Sophie Dessureault, MD, PhD, Lynn C. Moscinski, MD, William S. Dalton, PhD, MD, Eduardo M. Sotomayor, MD, Jin Cheng, Jianguo Tao, MD, PhD

Blood (2009) 114 (22): 1957.

https://doi.org/10.1182/blood.V114.22.1957.1957

Published: 2009

Journal Articles

Use of MicroRNA Expression Profiling to Identify Prognostic Subclasses in Mantle Cell Lymphoma: Mir-29 Family as New Prognostic Markers

Jianhong Lin, MD, Jianjun Zhao, MD, PhD, Tint Lwin, MD, PhD, Sophie Dessureault, MD, PhD, Lynn C. Moscinski, MD, William S. Dalton, MD, PhD, Eduardo Sotomayor, MD, Jin Cheng, MD, PhD, Jianguo Tao, MD, PhD

Blood (2008) 112 (11): 3744.

https://doi.org/10.1182/blood.V112.11.3744.3744

Published: 2008

NARROW

Heightened Endoplasmic-Reticulum Stress Is a Targetable Vulnerability of Malignant Plasma Cells in Multiple Myeloma

A Single Gene-Mediated Perturbation of the Human Genome Leads to Malignant Transformation in a Murine Transgenic Model

Modeling Lymphoplasmacytic Lymphoma/Waldenström Macroglobulinemia in Transgenic Mice Using Human MYD88 L256P Mutated Protein

Targeting the MALAT1/PARP1/LIG3 Complex Induces DNA Damage and Apoptosis in Multiple Myeloma Mouse Models

Germinal Center-Derived Lymphomas and Plasmacytomas in Mice with Targeted Deletion of MiR-15a/16-1 in Activated B Cells

Overexpression of BCL9, a Wnt/β-Catenin Transcriptional Co-Activator, in Transgenic Mice Promotes Spontaneous Development of B-Cell Malignancies

Apurinic/Apyrimidinic Endonuclease 1 Induced Genomic Instability Causes T-Cell Acute Lymphoblastic Leukemia in Zebrafish

Blocking Specific CD44 Splicing Variant Isoform Inhibits the Differentiation of Th-2 Cells through Interfering with IL-4/IL-4R Signaling Pathway

Follicular Dendritic Cell (FDC)-Induced Microrna-Mediated up-Regulation of PRDM1 and Down-Regulation of BCL6 in Germinal Center B Lymphocytes: A Potential Mechanism for B-Cell Differentiation.

MiR-29 MicroRNAs Regulate IGF-1R Expression and Contribute Mantle Cell Lymphoma Growth and Survival.

Use of MicroRNA Expression Profiling to Identify Prognostic Subclasses in Mantle Cell Lymphoma: Mir-29 Family as New Prognostic Markers

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American Society of Hematology

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American Society of Hematology

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