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Journal Articles

Phosphoglycerate Dehydrogenase Is Required for Germinal Center Formation and Is a Therapeutic Target in MYC- driven Lymphoma

Annalisa D'Avola, Nathalie Legrave, Mylene Tajan, Probir Chakravarty, Ryan Shearer, Hamish King, Eric Cheung, Andrew James Clear, Arief Suryono Gunawan, Lingling Zhang, Louisa James, James MacRae, John Gribben, Dinis Pedro Calado, Karen Vousden, John C. Riches

Blood (2021) 138 (Supplement 1): 717.

https://doi.org/10.1182/blood-2021-150442

Published: 2021

Journal Articles

Outcomes of patients with hematologic malignancies and COVID-19: a systematic review and meta-analysis of 3377 patients

Abi Vijenthira, Inna Y. Gong, Thomas A. Fox, Stephen Booth, Gordon Cook, Bruno Fattizzo, Fernando Martín-Moro, Jerome Razanamahery, John C. Riches, Jeff Zwicker, Rushad Patell, Marie Christiane Vekemans, Lydia Scarfò, Thomas Chatzikonstantinou, Halil Yildiz, Raphaël Lattenist, Ioannis Mantzaris, William A. Wood, Lisa K. Hicks

Blood (2020) 136 (25): 2881–2892.

https://doi.org/10.1182/blood.2020008824

Published: 2020

Includes: Supplemental data

Journal Articles

Mechanisms of PD-L1/PD-1–mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model

Fabienne McClanahan, John C. Riches, Shaun Miller, William P. Day, Eleni Kotsiou, Donna Neuberg, Carlo M. Croce, Melania Capasso, John G. Gribben

Blood (2015) 126 (2): 212–221.

https://doi.org/10.1182/blood-2015-02-626754

Published: 2015

Includes: Supplemental data

Journal Articles

Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations

John C. Riches, Conor J. O’Donovan, Sarah J. Kingdon, Fabienne McClanahan, Andrew J. Clear, Donna S. Neuberg, Lillian Werner, Carlo M. Croce, Alan G. Ramsay, Laura Z. Rassenti, Thomas J. Kipps, John G. Gribben

Blood (2014) 123 (26): 4101–4110.

https://doi.org/10.1182/blood-2014-01-552307

Published: 2014

Includes: Supplemental data

Journal Articles

Hanging tough: CMV-specific CD8 + T cells in CLL

John C. Riches, John G. Gribben

Blood (2014) 123 (5): 608–609.

https://doi.org/10.1182/blood-2013-12-540922

Published: 2014

Journal Articles

NK Cells From CLL Patients Exhibit Down-Regulation Of Interferon Response Genes That Can Be Reversed With Lenalidomide

John C. Riches, MD, Ajanthah Sangaralingam, PhD, Tracy Chaplin, Fabienne McClanahan, MD, Sameena Iqbal, Samir G. Agrawal, Alan G. Ramsay, PhD, John Gribben, MD, DSc

Blood (2013) 122 (21): 4131.

https://doi.org/10.1182/blood.V122.21.4131.4131

Published: 2013

Journal Articles

Trisomy 12 CLL Cells Have High Surface Expression Of Integrins Involved In Lymphocyte Trafficking But This Does Not Translate Into Improved LFA-1-Mediated Motility

Conor J. O'Donovan, Alan G. Ramsay, PhD, Fabienne McClanahan, MD, Laura Rassenti, PhD, Thomas J. Kipps, MD, PhD, John Gribben, MD, DSc, John C. Riches, MD

Blood (2013) 122 (21): 4159.

https://doi.org/10.1182/blood.V122.21.4159.4159

Published: 2013

Journal Articles

T-Cell Dysfunction In CLL Is Mediated Not Only By PD-1/PD-L1 But Also By PD-1/PD-L2 Interactions - Partial Functionality Is Maintained In PD-1 Defined CD8 Subsets and This Can Be Further Promoted By Ibrutinib Treatment

Fabienne McClanahan, MD, Shaun Miller, John C. Riches, MD, Essam Ghazaly, MD, PhD, William P. Day, Melania Capasso, PhD, John Gribben, MD, DSc

Blood (2013) 122 (21): 4120.

https://doi.org/10.1182/blood.V122.21.4120.4120

Published: 2013

Journal Articles

Intraclonal Complexity Of CLL Fractions In Cell Proliferation Rates, Gene Expression Signatures, and Responses To Autologous T-Cell Help In Peripheral blood and Secondary Lymphoid Tissues

Shih-Shih Chen, Thomas M. Herndon, MD, Claire Emson, PhD, John C. Riches, MD, Fabienne McClanahan, MD, Timothy Tong, Xiao-Jie Yan, MD PhD, Piers E.M. Patten, MD, PhD, John Gribben, MD, DSc, Adrian Wiestner, MD, PhD, Nicholas Chiorazzi, MD

Blood (2013) 122 (21): 115.

https://doi.org/10.1182/blood.V122.21.115.115

Published: 2013

Journal Articles

T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production

John C. Riches, Jeffrey K. Davies, Fabienne McClanahan, Rewas Fatah, Sameena Iqbal, Samir Agrawal, Alan G. Ramsay, John G. Gribben

Blood (2013) 121 (9): 1612–1621.

https://doi.org/10.1182/blood-2012-09-457531

Published: 2013

Includes: Supplemental data

Journal Articles

Inhibitory Ligands CD200, CD270, CD274 and CD276 Are Expressed On Eμ-TCL1 Transgenic Mouse Splenocytes and Are of Potential Relevance to Impaired T-Cell Function in Vivo

Fabienne McClanahan, MD, Cristina Ghirelli, PhD, Paul Greaves, MD, John C. Riches, MD, Rita Coutinho, MD, Alan G. Ramsay, PhD, John G Gribben

Blood (2012) 120 (21): 313.

https://doi.org/10.1182/blood.V120.21.313.313

Published: 2012

Journal Articles

Characterizing Immunophenotypic and Functional Pseudo-Exhaustion in T Cells From CLL Patients: The Impact of Lenalidomide

John C. Riches, MD, Jeff K. Davies, MD, PhD, Fabienne McClanahan, Rewas Fatah, Sameena Iqbal, Samir Agrawal, Alan G. Ramsay, PhD, John G Gribben

Blood (2012) 120 (21): 564.

https://doi.org/10.1182/blood.V120.21.564.564

Published: 2012

Journal Articles

Impact of Lenalidomide on Gene Expression Profiles of Malignant and Immune Cells in Patients with Chronic Lymphocytic Leukemia

John C. Riches, MD, Ajanthah Sangaralingam, PhD, Shahryar Kiaii, BSc, MSc, PhD, Tracy Chaplin, BSc, Demet Cekdemir, MD, Sameena Iqbal, Alan G. Ramsay, PhD, John G. Gribben, MD, DSc

Blood (2011) 118 (21): 976.

https://doi.org/10.1182/blood.V118.21.976.976

Published: 2011

Journal Articles

T-Cells From Patients with CLL Exhibit Phenotypic and Transcription Factor Profiles of Exhaustion Independent of CMV Serostatus

John C. Riches, MD, Jeff Davies, MD, PhD, Sameena Iqbal, Rewas Fatah, Samir Agrawal, Alan G. Ramsay, PhD, John G. Gribben, MD, DSc

Blood (2011) 118 (21): 1780.

https://doi.org/10.1182/blood.V118.21.1780.1780

Published: 2011

NARROW

Phosphoglycerate Dehydrogenase Is Required for Germinal Center Formation and Is a Therapeutic Target in MYC- driven Lymphoma

Outcomes of patients with hematologic malignancies and COVID-19: a systematic review and meta-analysis of 3377 patients

Mechanisms of PD-L1/PD-1–mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model

Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations

Hanging tough: CMV-specific CD8 + T cells in CLL

NK Cells From CLL Patients Exhibit Down-Regulation Of Interferon Response Genes That Can Be Reversed With Lenalidomide

Trisomy 12 CLL Cells Have High Surface Expression Of Integrins Involved In Lymphocyte Trafficking But This Does Not Translate Into Improved LFA-1-Mediated Motility

T-Cell Dysfunction In CLL Is Mediated Not Only By PD-1/PD-L1 But Also By PD-1/PD-L2 Interactions - Partial Functionality Is Maintained In PD-1 Defined CD8 Subsets and This Can Be Further Promoted By Ibrutinib Treatment

Intraclonal Complexity Of CLL Fractions In Cell Proliferation Rates, Gene Expression Signatures, and Responses To Autologous T-Cell Help In Peripheral blood and Secondary Lymphoid Tissues

T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production

Inhibitory Ligands CD200, CD270, CD274 and CD276 Are Expressed On Eμ-TCL1 Transgenic Mouse Splenocytes and Are of Potential Relevance to Impaired T-Cell Function in Vivo

Characterizing Immunophenotypic and Functional Pseudo-Exhaustion in T Cells From CLL Patients: The Impact of Lenalidomide

Impact of Lenalidomide on Gene Expression Profiles of Malignant and Immune Cells in Patients with Chronic Lymphocytic Leukemia

T-Cells From Patients with CLL Exhibit Phenotypic and Transcription Factor Profiles of Exhaustion Independent of CMV Serostatus

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American Society of Hematology

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ASH Publications

American Society of Hematology

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