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Joshua Hessler
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Journal Articles

Ibrutinib Is an Irreversible Molecular Inhibitor of Interleukin-2 Inducible Kinase: Expanding Therapeutic Potential and Modulating a Th1 Selective Pressure in CD4 T-Cells

Jason A Dubovsky, Ph.D, Kyle A Beckwith, B.S., Jennifer A. Woyach, MD, Samantha M. Jaglowski, MD, MPH, Joshua Hessler, Betty Y. Chang, PhD, Karilyn Larkin, Matthew R Stefanovski, B.S., Frank W Frissora, M.S., Lisa L. Smith, Kelly A Smucker, Joseph M. Flynn, DO, MPH, Jeffrey A. Jones, MD, MPH, Leslie A Andritsos, MD, Kami Maddocks, MD, Amy Lehman, Richard R. Furman, MD, Jeff Sharman, MD, Anjali Mishra, Ph.D., Michael A. Caligiuri, M.D., Joseph J. Buggy, PhD, Natarajan Muthusamy, DVM, Ph.D, Amy J Johnson, PhD, John C. Byrd, MD
Journal: Blood
Blood (2012) 120 (21): 775.
https://doi.org/10.1182/blood.V120.21.775.775
Published: 2012
Journal Articles

Dinaciclib (SCH727965) Is a Novel Cyclin Dependent Kinase Inhibitor That Promotes Selective Apoptosis In CLL Cells and Abrogates the Protective Effects of Microenvironment Cytokines

Amy J. Johnson, PhD, Lisa L. Smith, Amy J. Wagner, Joshua Hessler, Joseph M. Flynn, DO, MPH, Jeffrey A. Jones, MD, MPH, Xiaoli Zhang, Amy Lehman, David Jarjoura, Michael R. Grever, M.D., Rajat Bannerji, MD, PHD, John C. Byrd, MD
Journal: Blood
Blood (2010) 116 (21): 971.
https://doi.org/10.1182/blood.V116.21.971.971
Published: 2010
Journal Articles

Autophagy Is a Relevant Cellular Process In CLL and Contributes to Drug Resistance of Flavopiridol

Emilia Mahoney, MD, PhD, Amy J. Johnson, PhD, Amy J. Wagner, Joshua Hessler, Sneha V. Gupta, Sarah E.M. Herman, Leslie Andritsos, MD, Jeffrey A. Jones, MD, MPH, Joseph M. Flynn, DO, MPH, David M. Lucas, PhD, Michael R. Grever, M.D., John C. Byrd, MD
Journal: Blood
Blood (2010) 116 (21): 691.
https://doi.org/10.1182/blood.V116.21.691.691
Published: 2010
Journal Articles

The Cyclin Dependent Kinase Inhibitor SCH 727965 Demonstrates Promising Pre-Clinical and Early Clinical Activity in Chronic Lymphocytic Leukemia.

Joseph M. Flynn, DO, MPH, FACP, Amy J. Johnson, PhD, Leslie Andritsos, MD, Kristie A. Blum, MD, Jeffrey A. Jones, MD, MPH, Elizabeth A. Wiley, Weihong Hu, Joshua Hessler, Lisa L. Smith, David M. Lucas, PhD, Karen Small, Paul Statkevich, Michael R. Grever, MD, Rajat Bannerji, MD, PhD, John C. Byrd, MD
Journal: Blood
Blood (2009) 114 (22): 886.
https://doi.org/10.1182/blood.V114.22.886.886
Published: 2009
Journal Articles

Immunoliposomes Incorporated with Humanized Monoclonal Antibody, Milatuzumab, Induce Cell Death in CLL by Retention of the CD74 Receptor On the Surface of B Cells.

Erin K Hertlein, PhD, Georgia Triantafillou, Joshua Hessler, Xiaoli Zhang, David Jarjoura, David M. Lucas, PhD, Robert J Lee, Natarajan Muthusamy, PhD, David M Goldenberg, ScD, MD, John C. Byrd, MD
Journal: Blood
Blood (2009) 114 (22): 721.
https://doi.org/10.1182/blood.V114.22.721.721
Published: 2009