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Journal Articles

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Shok Ping Lim, Benedetta Costantini, Syed A. Mian, Pilar Perez Abellan, Shreyans Gandhi, Marc Martinez Llordella, Juan Jose Lozano, Rita Antunes dos Reis, Giovanni A. M. Povoleri, Thanos P. Mourikis, Ander Abarrategi, Linda Ariza-McNaughton, Susanne Heck, Jonathan M. Irish, Giovanna Lombardi, Judith C. W. Marsh, Dominique Bonnet, Shahram Kordasti, Ghulam J. Mufti

Blood (2020) 136 (7): 885–897.

https://doi.org/10.1182/blood.2019001347

Published: 2020

Includes: Supplemental data

Journal Articles

Concurrent Treatment of Aplastic Anaemia (AA) with Immunosuppressive Therapy and Paroxysmal Nocturnal Hemoglobinuria (PNH) with Eculizumab: A UK Experience

Morag Griffin, Austin Kulasekararaj, MD, Shreyans Gandhi, MD DNB, MRCP, FRCPath, Peter Hillmen, Talha Munir, Stephen John Richards, PhD, Louise Arnold, BSc, MA, Kathryn Riley, Katherine Pelton, Nana Benson-Quarm, B.Sc, Dip (Nursing), Isabel Duggins, Judith C. W. Marsh, MD FRCP, FRCPath, Anita Hill

Blood (2016) 128 (22): 2683.

https://doi.org/10.1182/blood.V128.22.2683.2683

Published: 2016

Journal Articles

Targeted Sequencing of 647 Patients with Myeloid Malignancies, Marrow Failures and Cytopenia: A Prospective Analysis

Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Steven Best, PhD, Aytug Kizilors, PhD, Shreyans Gandhi, MD DNB, MRCP, FRCPath, Victoria T Potter, Judith C. W. Marsh, MD FRCP, FRCPath, Nicholas Lea, PhD, Robin M. Ireland, FRCP, FRCPath, Ghulam J Mufti, MD

Blood (2016) 128 (22): 1981.

https://doi.org/10.1182/blood.V128.22.1981.1981

Published: 2016

Journal Articles

Towards the Potential Use of In Vitro Expanded Regulatory T-Cells (Tregs) in Aplastic Anemia (AA): Opportunities for Therapy

Benedetta Costantini, MD MPhil, Shahram Kordasti, MD PhD, Marc Martinez-Llordella, PhD, Giovanni Povoleri, MPhil, Judith C. W. Marsh, MD FRCP, FRCPath, Frederic Toulza, PhD, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2016) 128 (22): 2673.

https://doi.org/10.1182/blood.V128.22.2673.2673

Published: 2016

Journal Articles

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

Blood (2016) 128 (9): 1193–1205.

https://doi.org/10.1182/blood-2016-03-703702

Published: 2016

Includes: Supplemental data

Journal Articles

Telomere Length and Telomerase Assay Assist in Identifying Novel Telomere Gene Complex Mutations in a Cohort of Patients with Aplastic Anemia

Shreyans Gandhi, MBBS,MDDNB,MRCP,FRCPath, Jie Jiang, PhD, Nana Benson-Quarm, B.Sc, Dip (Nursing), Hanna Renshaw, MBBS, MA, Syed A Mian, BSc, M.Phil, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath, Judith C. W. Marsh, MD FRCP, FRCPath

Blood (2015) 126 (23): 667.

https://doi.org/10.1182/blood.V126.23.667.667

Published: 2015

Journal Articles

Busulfan-Dose Escalation in Reduced Intensity Stem Cell Transplantation (RIC-HSCT) Results in Good Outcomes for Patients with MDS and AML without Increased Toxicity

Anita Sarma, MBChB, BSc, MRCP, Victoria T Potter, MD FRCPA, FRACP, Jennifer Clay, BM BS, FRACP, FRCPA, Donal McLornan, MD PhD FRCPath, Hugues de Lavallade, MD PhD, Kavita Raj, Judith C. W. Marsh, Austin Kulasekararaj, Antonio Pagliuca, MD FRCP, FRCPath, Ghulam Mufti, MD DM, FRCP, FRCPath

Blood (2014) 124 (21): 1236.

https://doi.org/10.1182/blood.V124.21.1236.1236

Published: 2014

Journal Articles

Telomerase Gene Complex Mutations Are Common in Myelodysplastic Syndromes Patients

Mariam Ibañez, PhD, Jie Jiang, PhD, Shreyans Gandhi, MBBS,MDMNAMS, Mian Syed, Alexander E Smith, Steve Best, PhD, Nicholas Lea, Azim M Mohamedali, Momin Ahmed, Judith C. W. Marsh, Austin G Kulasekararaj, Ghulam J Mufti, FRCP, FRCPath, MD

Blood (2014) 124 (21): 1899.

https://doi.org/10.1182/blood.V124.21.1899.1899

Published: 2014

Journal Articles

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome

Austin G. Kulasekararaj, Jie Jiang, Alexander E. Smith, Azim M. Mohamedali, Syed Mian, Shreyans Gandhi, Joop Gaken, Barbara Czepulkowski, Judith C. W. Marsh, Ghulam J. Mufti

Blood (2014) 124 (17): 2698–2704.

https://doi.org/10.1182/blood-2014-05-574889

Published: 2014

Includes: Supplemental data

Journal Articles

Eltrombopag: a stem cell cookie?

Judith C. W. Marsh, Ghulam J. Mufti

Blood (2014) 123 (12): 1774–1775.

https://doi.org/10.1182/blood-2014-02-553404

Published: 2014

Journal Articles

Allogeneic hematopoietic stem cell transplantation in Fanconi anemia: the European Group for Blood and Marrow Transplantation experience

Régis Peffault de Latour, Raphael Porcher, Jean-Hugues Dalle, Mahmoud Aljurf, Elisabeth T. Korthof, Johanna Svahn, Roelof Willemze, Cristina Barrenetxea, Valerie Mialou, Jean Soulier, Mouhab Ayas, Rosi Oneto, Andrea Bacigalupo, Judith C. W. Marsh, Christina Peters, Gerard Socie, Carlo Dufour

Blood (2013) 122 (26): 4279–4286.

https://doi.org/10.1182/blood-2013-01-479733

Published: 2013

Includes: Supplemental data

Journal Articles

Management of the refractory aplastic anemia patient: what are the options?

Judith C. W. Marsh, Austin G. Kulasekararaj

Blood (2013) 122 (22): 3561–3567.

https://doi.org/10.1182/blood-2013-05-498279

Published: 2013

Journal Articles

Adverse Effect of Very Poor Cytogenetics and Monosomal Karyotype On Outcomes Following T-Deplete Reduced Intensity Conditioned Stem Cell Transplant for MDS and AML.

Pramila Krishnamurthy, MA MRCP FRCPath, Victoria T Potter, MBBS, FRCPA, FRACP, Austin G Kulasekararaj, Victor Noriega, Hugues de Lavallade, Robin M. Ireland, FRCP, FRCPath, Stephen Devereux, FRCP, FRCPath, Judith C. W. Marsh, MD, PhD, Robert E. Marcus, MBBS, FRCP, FRCPath, Barbara Czepulkowski, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD

Blood (2012) 120 (21): 3141.

https://doi.org/10.1182/blood.V120.21.3141.3141

Published: 2012

Journal Articles

Eculizumab in Paroxysmal Nocturnal Hemoglobinuria (PNH): A Report of All 153 Patients Treated in the UK

Anita Hill, MBChB, PhD, Richard J Kelly, MBChB, Austin G Kulasekararaj, MBBS, MD, Shreyans A Gandhi, MBBS, MD, Lindsay D Mitchell, MBChB, Modupe Elebute, MBChB, MD, Stephen John Richards, PhD, Matthew Cullen, MSc, Louise M Arnold, RN, BSc, Joanna Large, RN, BSc, Alexandra Wood, RN, BSc, Gemma L Brooksbank, RN, BSc, Tracy Downing, Claire McKinley, BSc, Dena Cohen, BSc, MSc, Walter M Gregory, PhD, Judith C. W. Marsh, MD, PhD, Ghulam J. Mufti, MD, Peter Hillmen, MBChB, PhD

Blood (2012) 120 (21): 3472.

https://doi.org/10.1182/blood.V120.21.3472.3472

Published: 2012

Journal Articles

Allogeneic Stem Cell Transplantation for Accelerated/Blastic Phase Philadelphia-Chromosome Negative MPN

Anjum Bashir Khan, MBChB, MRCP, Donal McLornan, MD, PhD, Yogesh Jethava, MB, MRCP, MD, FRCPath, Kavita Raj, MD, PhD, MRCP, FRCPath, Victoria T Potter, MBBS, FRCPA, FRACP, Hugues de Lavallade, MD, Majid A Kazmi, BmedBiol MB ChB MRCP (UK) MRCPath, ZiYi Lim, MD, Judith C. W. Marsh, Prof MD PhD, Sangeeta Atwal, MBBS MRCP FRCPath, Victor Noriega, MD, Claire N Harrison, DM FRCP FRCPath, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD

Blood (2012) 120 (21): 4532.

https://doi.org/10.1182/blood.V120.21.4532.4532

Published: 2012

Journal Articles

HCT-CI Is Not a Useful Predictor for Non Relapse Mortality in Older Patients (>60 years old) Receiving RIC Transplant for AML or MDS

Victor Noriega, MD, Hugues de Lavallade, MD, Victoria T Potter, MBBS, FRCPA, FRACP, Pramila Krishnamurthy, Judith C. W. Marsh, Prof MD PhD, Stephen Devereux, FRCP, FRCPath, Ph.D., Robert E. Marcus, MBBS, FRCP, FRCPath, Kavita Raj, Donal McLornan, MD, PhD, Anjum Bashir Khan, MBChB, MRCP, Sangeeta Atwal, MBBS MRCP FRCPath, Robin M. Ireland, FRCP, FRCPath, Deborah Yallop, BSc, FRCPath, MB, BS, MRCP, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J Mufti, FRCP, FRCPath, M.D.

Blood (2012) 120 (21): 4158.

https://doi.org/10.1182/blood.V120.21.4158.4158

Published: 2012

Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation in Paroxysmal Nocturnal Hemoglobinuria: A Transplant Versus No Transplant Matched Comparison Study On Behalf of the Severe Aplastic Anemia Working Party (SAA WP) of the European Group for Blood and Marrow Transplantation (EBMT) Group and the French Society of Hematology (SFH)

Régis Peffault de Latour, Hubert Schrezenmeier, Andrea Bacigalupo, MD, Didier Blaise, MD, Carmino Antonio De Souza, Stephane Vigouroux, MD, Roelof Willemze, Louis Terriou, André Tichelli, Mohamad Mohty, Sophie De Guibert, Judith C. W. Marsh, Prof MD PhD, Jakob Passweg, Jean-Yves Mary, Gerard Socie

Blood (2011) 118 (21): 2403.

https://doi.org/10.1182/blood.V118.21.2403.2403

Published: 2011

Journal Articles

Telomere Length In MDS Patients Bone Marrow Is Highly Correlated with Complex Cytogenetics, IPSS Risk Groups and Transfusion Dependency,

Jie Jiang, PhD, Austin G Kulasekararaj, Pramila Krishnamurthy, Alexander E Smith, PhD, Syed A Mian, Shreyans Gandhi, Janet Hayden, Joop Gaken, Modupe Elebute, Robin M. Ireland, FRCP, FRCPath, ZiYi Lim, MD, Judith C. W. Marsh, Prof MD PhD, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 3826.

https://doi.org/10.1182/blood.V118.21.3826.3826

Published: 2011

Journal Articles

Long-Term Outcome After Matched Allogeneic Hematopoietic Stem Cell Transplantation for Fanconi Anemia On Behalf of the FA Committee of the Severe Aplastic Anemia Working Party (SAA WP) and the Pediatric Working Party of the European Group for Blood and Marrow Transplantation (EBMT)

Régis Peffault de Latour, Raphael Porcher, Jean-Hugues Dalle, Mahmoud Aljurf, Elisabeth T Korthof, MD, Johanna Svahn, Roelof Willemze, C Barrenetxea, Valerie Mialou, Jean Soulier, MD, Enrico Cappelli, Judith C. W. Marsh, Prof MD PhD, Christina Peters, MD, Gerard Socie, Carlo Dufour, MD

Blood (2011) 118 (21): 325.

https://doi.org/10.1182/blood.V118.21.325.325

Published: 2011

Journal Articles

TP53 Mutations Are Restricted Predominantly to 5q- Syndrome and Myelodysplastic Syndrome Patients with Complex Cytogenetics, and Correlate with Adverse Prognosis

Austin G Kulasekararaj, Alexander E Smith, PhD, Syed A Mian, Pramila Krishnamurthy, Azim M Mohamedali, PhD, Nicholas C Lea, PhD, Janet Hayden, Joop Gaken, Modupe Elebute, Robin M. Ireland, FRCP, FRCPath, Sabine Pomplun, ZiYi Lim, MD, Judith C. W. Marsh, Prof MD PhD, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 792.

https://doi.org/10.1182/blood.V118.21.792.792

Published: 2011

NARROW

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Concurrent Treatment of Aplastic Anaemia (AA) with Immunosuppressive Therapy and Paroxysmal Nocturnal Hemoglobinuria (PNH) with Eculizumab: A UK Experience

Targeted Sequencing of 647 Patients with Myeloid Malignancies, Marrow Failures and Cytopenia: A Prospective Analysis

Towards the Potential Use of In Vitro Expanded Regulatory T-Cells (Tregs) in Aplastic Anemia (AA): Opportunities for Therapy

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

Telomere Length and Telomerase Assay Assist in Identifying Novel Telomere Gene Complex Mutations in a Cohort of Patients with Aplastic Anemia

Busulfan-Dose Escalation in Reduced Intensity Stem Cell Transplantation (RIC-HSCT) Results in Good Outcomes for Patients with MDS and AML without Increased Toxicity

Telomerase Gene Complex Mutations Are Common in Myelodysplastic Syndromes Patients

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome

Eltrombopag: a stem cell cookie?

Allogeneic hematopoietic stem cell transplantation in Fanconi anemia: the European Group for Blood and Marrow Transplantation experience

Management of the refractory aplastic anemia patient: what are the options?

Adverse Effect of Very Poor Cytogenetics and Monosomal Karyotype On Outcomes Following T-Deplete Reduced Intensity Conditioned Stem Cell Transplant for MDS and AML.

Eculizumab in Paroxysmal Nocturnal Hemoglobinuria (PNH): A Report of All 153 Patients Treated in the UK

Allogeneic Stem Cell Transplantation for Accelerated/Blastic Phase Philadelphia-Chromosome Negative MPN

HCT-CI Is Not a Useful Predictor for Non Relapse Mortality in Older Patients (>60 years old) Receiving RIC Transplant for AML or MDS

Telomere Length In MDS Patients Bone Marrow Is Highly Correlated with Complex Cytogenetics, IPSS Risk Groups and Transfusion Dependency,

Long-Term Outcome After Matched Allogeneic Hematopoietic Stem Cell Transplantation for Fanconi Anemia On Behalf of the FA Committee of the Severe Aplastic Anemia Working Party (SAA WP) and the Pediatric Working Party of the European Group for Blood and Marrow Transplantation (EBMT)

TP53 Mutations Are Restricted Predominantly to 5q- Syndrome and Myelodysplastic Syndrome Patients with Complex Cytogenetics, and Correlate with Adverse Prognosis

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American Society of Hematology

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American Society of Hematology

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