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Journal Articles

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Shok Ping Lim, Benedetta Costantini, Syed A. Mian, Pilar Perez Abellan, Shreyans Gandhi, Marc Martinez Llordella, Juan Jose Lozano, Rita Antunes dos Reis, Giovanni A. M. Povoleri, Thanos P. Mourikis, Ander Abarrategi, Linda Ariza-McNaughton, Susanne Heck, Jonathan M. Irish, Giovanna Lombardi, Judith C. W. Marsh, Dominique Bonnet, Shahram Kordasti, Ghulam J. Mufti

Blood (2020) 136 (7): 885–897.

https://doi.org/10.1182/blood.2019001347

Published: 2020

Includes: Supplemental data

Journal Articles

Neoantigens in MDS Are Associated with Two Novel CD4+ T Cell Subsets and Improved Overall Survival

Thomas Coats, MD, Alexander E Smith, PhD, Athanasios Mourikis, Tala Shahin, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Steve Best, PhD, Sneha Chitre, Richard Ellis, Nedyalko Petrov, Susanne Heck, Jonathan Michael Irish, PhD, Shahram Kordasti, MD PhD, Ghulam Mufti, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 2958.

https://doi.org/10.1182/blood.V130.Suppl_1.2958.2958

Published: 2017

Journal Articles

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

Blood (2016) 128 (9): 1193–1205.

https://doi.org/10.1182/blood-2016-03-703702

Published: 2016

Includes: Supplemental data

Journal Articles

High Resolution Mass Cytometry (CyTOF) in Aplastic Anaemia (AA) Can Identify an Aberrant Treg Subset with Pro-Inflammatory Properties, Predicting Poor Response to Immunosuppressive Therapy

Shahram Kordasti, MD PhD, Thomas Seidl, Richard J Ellis, PhD, Austin Kulasekararaj, Xingmin Feng, PhD, Danielle M. Townsley, MD MSc, Susanne Heck, PhD, Neal S. Young, MD, Judith C Marsh, MD, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2014) 124 (21): 1600.

https://doi.org/10.1182/blood.V124.21.1600.1600

Published: 2014

Journal Articles

Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents

Weili Bao, James B. Bussel, Susanne Heck, Wu He, Marissa Karpoff, Nayla Boulad, Karina Yazdanbakhsh

Blood (2010) 116 (22): 4639–4645.

https://doi.org/10.1182/blood-2010-04-281717

Published: 2010

Includes: Supplemental data

Journal Articles

Altered Regulation of Immune Responses in Alloimmunized Chronically Transfused Patients with Sickle Cell Disease.

Weili Bao, MS, Susanne Heck, PhD, Wu He, PhD, Maureen Licursi, MSN,CPNP, Genia Billote, RN, MPH, MFA, Hannah Stephens, RN, Joan Uehlinger, MD, Margaret T. Lee, MD, Sujit Sheth, MD, Karina Yazdanbakhsh, PhD

Blood (2009) 114 (22): 637.

https://doi.org/10.1182/blood.V114.22.637.637

Published: 2009

Journal Articles

Increased Regulatory T Cell Function in a Mouse Model of Beta-Thalassemia.

Weili Bao, MS, Susanne Heck, PhD, Wu He, PhD, Karina Yazdanbakhsh, PhD

Blood (2009) 114 (22): 638.

https://doi.org/10.1182/blood.V114.22.638.638

Published: 2009

Journal Articles

Improved Regulatory T Cell Activity in Patients with Chronic Immune Thrombocytopenia Purpura Treated with Thrombopoietic Agents.

Weili Bao, MS, Susanne Heck, PhD, Marissa Karpoff, BS, James B. Bussel, MD, Karina Yazdanbakhsh, PhD

Blood (2009) 114 (22): 684.

https://doi.org/10.1182/blood.V114.22.684.684

Published: 2009

Journal Articles

Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT

Qiaozhen Kang, Yu Yu, Xinhong Pei, Richard Hughes, Susanne Heck, Xihui Zhang, Xinhua Guo, Gregory Halverson, Narla Mohandas, Xiuli An

Blood (2009) 113 (24): 6128–6137.

https://doi.org/10.1182/blood-2008-10-182329

Published: 2009

Includes: Supplemental data

Journal Articles

Regulatory T-cell status in red cell alloimmunized responder and nonresponder mice

Weili Bao, Jin Yu, Susanne Heck, Karina Yazdanbakhsh

Blood (2009) 113 (22): 5624–5627.

https://doi.org/10.1182/blood-2008-12-193748

Published: 2009

Includes: Supplemental data

Journal Articles

Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura

Jin Yu, Susanne Heck, Vivek Patel, Jared Levan, Yu Yu, James B. Bussel, Karina Yazdanbakhsh

Blood (2008) 112 (4): 1325–1328.

https://doi.org/10.1182/blood-2008-01-135335

Published: 2008

Journal Articles

Defective Circulating CD25 Regulatory T Cells in Patients with Chronic Immune Thrombocytopenic Purpura.

Jin Yu, MD, Vivek Patel, BS, Susanne Heck, PhD, Jared Levan, BS, Yu Yu, MD, James B. Bussel, MD, Karina Yazdanbakhsh, PhD

Blood (2007) 110 (11): 570.

https://doi.org/10.1182/blood.V110.11.570.570

Published: 2007

Journal Articles

Cord Blood (CB) CD34 + and CD3 + Cells with Decreasing Levels of Their Mitochondrial Potential Are Not Detectable with 7-AAD, Have Impaired Function and Ultrastructural Morphology Characteristic of Early Apoptosis.

Maria S. Albano, PhD, Andromachi Scaradavou, MD, Susanne Heck, MD, Cladd E. Stevens, MD, Pablo Rubinstein, MD

Blood (2007) 110 (11): 1208.

https://doi.org/10.1182/blood.V110.11.1208.1208

Published: 2007

Journal Articles

Differences in Regulatory T Cell Function in Alloimmunized Versus Non-Alloimmunized Mice Following Multiple Red Cell Transfusions.

Jin Yu, MD, Susanne Heck, PhD, Karina Yazdanbakhsh, PhD

Blood (2007) 110 (11): 452.

https://doi.org/10.1182/blood.V110.11.452.452

Published: 2007

Journal Articles

Prevention of Red Cell Alloimmunization by CD25 Regulatory T Cells.

Karina Yazdanbakhsh, PhD, Xiaoying Zheng, MSc, Jin Yu, MD, Susanne Heck, PhD

Blood (2006) 108 (11): 22.

https://doi.org/10.1182/blood.V108.11.22.22

Published: 2006

Journal Articles

Distinguishable live erythroid and myeloid cells in β-globin ECFP x lysozyme EGFP mice

Susanne Heck, Olga Ermakova, Hiromi Iwasaki, Koichi Akashi, Chiao-Wang Sun, Thomas M. Ryan, Tim Townes, Thomas Graf

Blood (2003) 101 (3): 903–906.

https://doi.org/10.1182/blood-2002-06-1861

Published: 2003

Journal Articles

Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages

Nicole Faust, Florencio Varas, Louise M. Kelly, Susanne Heck, Thomas Graf

Blood (2000) 96 (2): 719–726.

https://doi.org/10.1182/blood.V96.2.719

Published: 2000

NARROW

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Neoantigens in MDS Are Associated with Two Novel CD4+ T Cell Subsets and Improved Overall Survival

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

High Resolution Mass Cytometry (CyTOF) in Aplastic Anaemia (AA) Can Identify an Aberrant Treg Subset with Pro-Inflammatory Properties, Predicting Poor Response to Immunosuppressive Therapy

Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents

Altered Regulation of Immune Responses in Alloimmunized Chronically Transfused Patients with Sickle Cell Disease.

Increased Regulatory T Cell Function in a Mouse Model of Beta-Thalassemia.

Improved Regulatory T Cell Activity in Patients with Chronic Immune Thrombocytopenia Purpura Treated with Thrombopoietic Agents.

Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT

Regulatory T-cell status in red cell alloimmunized responder and nonresponder mice

Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura

Defective Circulating CD25 Regulatory T Cells in Patients with Chronic Immune Thrombocytopenic Purpura.

Cord Blood (CB) CD34 + and CD3 + Cells with Decreasing Levels of Their Mitochondrial Potential Are Not Detectable with 7-AAD, Have Impaired Function and Ultrastructural Morphology Characteristic of Early Apoptosis.

Differences in Regulatory T Cell Function in Alloimmunized Versus Non-Alloimmunized Mice Following Multiple Red Cell Transfusions.

Prevention of Red Cell Alloimmunization by CD25 Regulatory T Cells.

Distinguishable live erythroid and myeloid cells in β-globin ECFP x lysozyme EGFP mice

Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages

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American Society of Hematology

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ASH Publications

American Society of Hematology

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