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Journal Articles

Dynamic Oscillation of Tetraspanin CD9 Orchestrates Engraftment and Mobilization of Human Hematopoietic Stem/Progenitor Cells

Wing Hei Ng, Chi Zhang, Han Wang, Kathy Yuen Yee Chan, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 5575.

https://doi.org/10.1182/blood-2023-189365

Published: 2023

Journal Articles

The Topoisomerase-I Inhibitor Gimatecan Exhibits Potent and Selective Activities Against B-Cell Precursor Acute Lymphoblastic Leukemia with a Favorable Cardiotoxicity Profile

Han Wang, Kathy Yuen Yee Chan, Po Yi Lee, Chi Zhang, Hung Sing LI, Wai Man Leung, Maxwell Kwok, Po Yee Chung, Wing Hei Ng, John Tak Kit Cheung, Wai Yip Lam, Benjamin Li, Chi Kong Li, Ellen Poon, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 4252.

https://doi.org/10.1182/blood-2023-189498

Published: 2023

Journal Articles

Epigenetic Silencing of CD9 Shapes a New Mechanism to Render Differentiation Block and Immune Evasion in Pediatric Acute Myeloid Leukemia

Yaqun Xu, Kathy Yuen Yee Chan, Siu Ping Fok, Yixuan Wu, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 2763.

https://doi.org/10.1182/blood-2023-188666

Published: 2023

Journal Articles

CD38 Is a Functional Partner of CD9 in B-Cell Precursor Acute Lymphoblastic Leukemia

Po Yee Chung, Kathy Yuen Yee Chan, Chi Zhang, Yaqun Xu, Wing Hei Ng, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 1611.

https://doi.org/10.1182/blood-2023-188847

Published: 2023

Journal Articles

Drug Response Profiling of Childhood T-Cell Acute Lymphoblastic Leukemia to Inform Functional Precision Medicine

Guanglan Lin, Kathy Yuen Yee Chan, Qiwei SUN, Wing Kwan Leung, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 2975.

https://doi.org/10.1182/blood-2023-190580

Published: 2023

Journal Articles

The Tetraspanin CD9 Shapes Glucocorticoid Sensitivity in Pediatric B-Precursor Acute Lymphoblastic Leukemia

Chi Zhang, Kathy Yuen Yee Chan, John Tak Kit Cheung, Wing Hei Ng, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 2973.

https://doi.org/10.1182/blood-2023-189578

Published: 2023

Journal Articles

Prognostic Features of CD9 in Childhood Acute Lymphoblastic Leukemia - a Retrospective Analysis of a Nation-Wide Multicenter Study in China

Kathy Yuen Yee Chan, Jiaoyang Cai, Yu Liu, Jun J. Yang, Ching-Hon Pui, Shuhong Shen, Chi Kong Li, Kam Tong Leung

Blood (2023) 142 (Supplement 1): 2836.

https://doi.org/10.1182/blood-2023-191098

Published: 2023

Journal Articles

Histone Hypoacetylation-Driven CD9 Repression Arrests Differentiation and Evades Immunosurveillance in Pediatric Acute Myeloid Leukemia

Yaqun Xu, Kathy Chan, Siu Ping Fok, Toni Ki Fong Man, Chi Kong Li, Kam Tong Leung

Blood (2021) 138 (Supplement 1): 3311.

https://doi.org/10.1182/blood-2021-152503

Published: 2021

Journal Articles

Integrative Drug and Genomic Profiling Identify Therapeutic Vulnerabilities and Inform Precision Medicine for Pediatric Acute Myeloid Leukemia

Han Wang, Kathy Chan, Po Yi Lee, Alex WK Leung, Chi Kong Li, Kam Tong Leung

Blood (2021) 138 (Supplement 1): 2297.

https://doi.org/10.1182/blood-2021-147693

Published: 2021

Journal Articles

R4 Rgs Subfamily Proteins Suppress Engraftment and Regulate SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells

Kathy Chan, PhD, Tsin Sik Wong, Mphil, Karen Li, PhD, Xiao-Bing Zhang, PhD, Ronald Wang, PhD, King Yiu Lee, PhD, Frankie Wai Tsoi Cheng, MD, Chi Kong Li, MBBS,MD, Kam Tong Leung, PhD

Blood (2019) 134 (Supplement_1): 1927.

https://doi.org/10.1182/blood-2019-129498

Published: 2019

Journal Articles

Engraftment and SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells Are Regulated By R4 Rgs Subfamily Proteins

Tsin Sik Wong, BSc, Kathy Yuen Yee Chan, PhD, Karen Li, PhD, Xiao-Bing Zhang, PhD, Ting Fan Leung, MD, Chi Kong Li, MD, Kam Tong Leung, PhD

Blood (2017) 130 (Supplement 1): 3752.

https://doi.org/10.1182/blood.V130.Suppl_1.3752.3752

Published: 2017

Journal Articles

CD9 Blockade Effectively Suppresses Disease Progression of Pediatric B-Precursor Acute Lymphoblastic Leukemia and Enhances Chemosensitivity

Chi Zhang, MSc, Kam Tong Leung, PhD, Karen Li, PhD, Kathy Yuen Yee Chan, PhD, Alex Wing Kwan Leung, MRCPCH, John Tak Kit Cheung, BSc, Frankie Wai Tsoi Cheng, MD, Chi Kong Li, MD

Blood (2017) 130 (Supplement 1): 1327.

https://doi.org/10.1182/blood.V130.Suppl_1.1327.1327

Published: 2017

Journal Articles

R4 Rgs Subfamily Proteins Negatively Regulates SDF-1/CXCR4 Signaling in CD34+ Hematopoietic Stem and Progenitor Cells

Kam Tong Leung, PhD, Yorky Tsin Sik Wong, BSc, Karen Li, PhD, Kathy Yuen Yee Chan, PhD, Xiao-Bing Zhang, PhD, Ting Fan Leung, MD, Pak Cheung Ng, MD FRCPCH, Chi Kong Li, MD

Blood (2016) 128 (22): 5048.

https://doi.org/10.1182/blood.V128.22.5048.5048

Published: 2016

Journal Articles

The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity

Kam Tong Leung, PhD, Karen Li, PhD, Yorky Tsin Sik Wong, BSc, Kathy Yuen Yee Chan, PhD, Xiao-Bing Zhang, PhD, Alex Wing Kwan Leung, MRCPCH, Tak Yeung Leung, MD, Kam Sze Tsang, PhD, Pak Cheung Ng, MD FRCPCH, Chi Kong Li, MD

Blood (2015) 126 (23): 1169.

https://doi.org/10.1182/blood.V126.23.1169.1169

Published: 2015

Journal Articles

RGS1 and RGS13 Regulate SDF-1-Mediated Responses and Homing in Human Cord Blood CD34+ Hematopoietic Stem/Progenitor Cells

Yorky Tsin Sik Wong, BSc, Kam Tong Leung, PhD, Karen Li, PhD, Kathy Yuen Yee Chan, PhD, Xiao-Bing Zhang, PhD, Tak Yeung Leung, MD, Kam Sze Tsang, PhD, Ting Fan Leung, MD, Pak Cheung Ng, MD FRCPCH, Chi Kong Li, MD

Blood (2015) 126 (23): 2371.

https://doi.org/10.1182/blood.V126.23.2371.2371

Published: 2015

Journal Articles

Gene Expressional Profile of Neonatal Neutrophils in Response to Bacterial Lipopolysaccharide (LPS) and Possible Mechanism of Transcription Factor NR4A2 on the Immune Signal Cascade

Kathy Yuen Yee Chan, PhD, Ka Ian Tam, PhD, Kam Tong Leung, PhD, Tak Yeung Leung, MD, Karen Li, PhD, Chi Kong Li, MD, Pak Cheung Ng, MD FRCPCH

Blood (2015) 126 (23): 995.

https://doi.org/10.1182/blood.V126.23.995.995

Published: 2015

Journal Articles

Decreased Frequency of Circulating CD34+ Hematopoietic Stem/Progenitor Cells in Preterm Infants with Late-Onset Systemic Bacterial Infection

Kam Tong Leung, PhD, Hugh Simon Lam, MD, Kathy Yuen Yee Chan, PhD, Raymond Pui On Wong, MPhil, Karen Li, PhD, Chi Kong Li, MD, Pak Cheung Ng, MD

Blood (2014) 124 (21): 2906.

https://doi.org/10.1182/blood.V124.21.2906.2906

Published: 2014

Journal Articles

A Possible Role Of The Tetraspanin CD9 In Bone Marrow Retention and Engraftment Of Human CD34+ Hematopoietic Stem/Progenitor Cells

Kam Tong Leung, PhD, Karen Li, PhD, Kam Sze Kent Tsang, PhD, Kathy Yuen Yee Chan, PhD, Pak Cheung Ng, MD, Chi Kong Li, MD

Blood (2013) 122 (21): 3237.

https://doi.org/10.1182/blood.V122.21.3237.3237

Published: 2013

Journal Articles

The tetraspanin CD9 regulates migration, adhesion, and homing of human cord blood CD34 + hematopoietic stem and progenitor cells

Kam Tong Leung, Kathy Yuen Yee Chan, Pak Cheung Ng, Tze Kin Lau, Wui Man Chiu, Kam Sze Tsang, Chi Kong Li, Carrie Ka Lai Kong, Karen Li

Blood (2011) 117 (6): 1840–1850.

https://doi.org/10.1182/blood-2010-04-281329

Published: 2011

Includes: Supplemental data

Journal Articles

Activation of the JNK Pathway Mediates Chemoresistance in T-Cell Acute Lymphoblastic Leukemia by Phosphorylation and Proteosomal Degradation of Bim EL .

Kam Tong Leung, MPhil, Karen Kwai Har Li, PhD, Samuel Sai Ming Sun, PhD, Paul Kay Sheung Chan, MD, Yum Shing Wong, PhD, Vincent Eng Choon Ooi, PhD, Lawrence Chi Ming Chiu, PhD

Blood (2007) 110 (11): 2372.

https://doi.org/10.1182/blood.V110.11.2372.2372

Published: 2007

NARROW

Dynamic Oscillation of Tetraspanin CD9 Orchestrates Engraftment and Mobilization of Human Hematopoietic Stem/Progenitor Cells

The Topoisomerase-I Inhibitor Gimatecan Exhibits Potent and Selective Activities Against B-Cell Precursor Acute Lymphoblastic Leukemia with a Favorable Cardiotoxicity Profile

Epigenetic Silencing of CD9 Shapes a New Mechanism to Render Differentiation Block and Immune Evasion in Pediatric Acute Myeloid Leukemia

CD38 Is a Functional Partner of CD9 in B-Cell Precursor Acute Lymphoblastic Leukemia

Drug Response Profiling of Childhood T-Cell Acute Lymphoblastic Leukemia to Inform Functional Precision Medicine

The Tetraspanin CD9 Shapes Glucocorticoid Sensitivity in Pediatric B-Precursor Acute Lymphoblastic Leukemia

Prognostic Features of CD9 in Childhood Acute Lymphoblastic Leukemia - a Retrospective Analysis of a Nation-Wide Multicenter Study in China

Histone Hypoacetylation-Driven CD9 Repression Arrests Differentiation and Evades Immunosurveillance in Pediatric Acute Myeloid Leukemia

Integrative Drug and Genomic Profiling Identify Therapeutic Vulnerabilities and Inform Precision Medicine for Pediatric Acute Myeloid Leukemia

R4 Rgs Subfamily Proteins Suppress Engraftment and Regulate SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells

Engraftment and SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells Are Regulated By R4 Rgs Subfamily Proteins

CD9 Blockade Effectively Suppresses Disease Progression of Pediatric B-Precursor Acute Lymphoblastic Leukemia and Enhances Chemosensitivity

R4 Rgs Subfamily Proteins Negatively Regulates SDF-1/CXCR4 Signaling in CD34+ Hematopoietic Stem and Progenitor Cells

The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity

RGS1 and RGS13 Regulate SDF-1-Mediated Responses and Homing in Human Cord Blood CD34+ Hematopoietic Stem/Progenitor Cells

Gene Expressional Profile of Neonatal Neutrophils in Response to Bacterial Lipopolysaccharide (LPS) and Possible Mechanism of Transcription Factor NR4A2 on the Immune Signal Cascade

Decreased Frequency of Circulating CD34+ Hematopoietic Stem/Progenitor Cells in Preterm Infants with Late-Onset Systemic Bacterial Infection

A Possible Role Of The Tetraspanin CD9 In Bone Marrow Retention and Engraftment Of Human CD34+ Hematopoietic Stem/Progenitor Cells

The tetraspanin CD9 regulates migration, adhesion, and homing of human cord blood CD34 + hematopoietic stem and progenitor cells

Activation of the JNK Pathway Mediates Chemoresistance in T-Cell Acute Lymphoblastic Leukemia by Phosphorylation and Proteosomal Degradation of Bim EL .

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American Society of Hematology

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American Society of Hematology

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