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Journal Articles

Activated Natural Killer Cells Are Associated with Poor Clinical Prognosis in High-Risk B- and T- Cell Acute Lymphoblastic Leukemia

Caroline Duault, PharmD, PhD, Anil Kumar, PhD, Adeleh Taghi Khani, PhD, Sung June Lee, BA, Lu Yang, PhD, Min Huang, PhD, Christian Hurtz, PhD, Bryan Manning, BS, Lucy Ghoda, PhD, Tinisha McDonald, BS, Norman J. Lacayo, MD, Kathleen M. Sakamoto, MD PhD, Martin P. Carroll, MD, Guido Marcucci, MD, Jianhua Yu, PhD, Michael A. Caligiuri, MD, Holden T. Maecker, PhD, Srividya Swaminathan, PhD

Blood (2020) 136 (Supplement 1): 39.

https://doi.org/10.1182/blood-2020-140044

Published: 2020

Journal Articles

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-142270

Published: 2020

Journal Articles

Genetic Modulators of Niclosamide Sensitivity and Resistance in Acute Myeloid Leukemia

Anna Wojcicki, BS, Hee-Don Chae, PhD, Kyuho Han, PhD, Minyoung Youn, PhD, Mark C Wilkes, PhD, Norman J. Lacayo, MD, Michael Bassik, PhD, Kathleen M. Sakamoto, MD PhD

Blood (2020) 136 (Supplement 1): 29.

https://doi.org/10.1182/blood-2020-137340

Published: 2020

Journal Articles

Metformin Upregulates Mir-26a to Improve Erythropoiesis in Preclinical Models of Diamond Blackfan Anemia through Suppression of Nlk Expression

Mark C Wilkes, PhD, Kavitha Siva, PhD, Jacqueline D Mercado, Ethan Patrick Wentworth, Mallika Saxena, Jun Chen, MD PhD, Anupama Narla, MD, Bertil Glader, MD PhD, Shuo Lin, PhD, Manuel Serrano, PhD, Johan Flygare, MD PhD, Kathleen M. Sakamoto, MD PhD

Blood (2020) 136 (Supplement 1): 7.

https://doi.org/10.1182/blood-2020-137170

Published: 2020

Journal Articles

SATB1 Regulates GATA1 Protein Expression in Early Hematopoiesis and Is Deregulated in Diamond Blackfan Anemia

Mark C Wilkes, PhD, Hee-Don Chae, PhD, Ethan Patrick Wentworth, Toshinobu Nishimura, PhD, Anupama Narla, MD, Bertil Glader, MD PhD, Hiromitsu Nakauchi, Joanna Wysocka, Kathleen M. Sakamoto, MD PhD

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-140437

Published: 2020

Journal Articles

Pp90RSK Isoforms Play Distinct Roles during Hematopoiesis

Minyoung Youn, PhD, Hee-Don Chae, PhD, Jesus Omar Gomez, Kathleen M. Sakamoto, MD PhD

Blood (2020) 136 (Supplement 1): 13.

https://doi.org/10.1182/blood-2020-142251

Published: 2020

Journal Articles

Targeting of Calbindin 1 (CALB1) Rescues Erythropoiesis in a Human Model of Diamond Blackfan Anemia: Implications for Novel Therapies

Nan of Wang, PhD, Corinne Marie Lavasseur, BA, Hongxia Yan, MS, Scott Younger, PhD, Bertil Glader, MD PhD, Kathleen M. Sakamoto, MD PhD, Lionel Blanc, PhD, Anupama Narla, MD

Blood (2020) 136 (Supplement 1): 4.

https://doi.org/10.1182/blood-2020-139823

Published: 2020

Journal Articles

Pharmacological Inhibition of Nemo-like Kinase Rescues mTOR-Mediated Translation and Primes Progenitors for Leucine-Stimulated Erythroid Expansion in Pre-Clinical Models of Diamond Blackfan Anemia

Mark C Wilkes, PhD, Jacqueline D Mercado, Mallika Saxena, Jun Chen, MD PhD, Kavitha Siva, PhD, Hee-Don Chae, PhD, Minyoung Youn, PhD, Ethan Patrick Wentworth, Kevin Jung, Ryan Sathianathen, Hiral Patel, Bertil Glader, MD PhD, Anupama Narla, MD, Claire E Repellin, PhD, Hanna T Gazda, MD PhD, Manuel Serrano, PhD, Johan Flygare, MD PhD, Kathleen M. Sakamoto, MD PhD

Blood (2019) 134 (Supplement_1): 455.

https://doi.org/10.1182/blood-2019-129570

Published: 2019

Journal Articles

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Blood (2018) 132 (Supplement 1): 4246.

https://doi.org/10.1182/blood-2018-99-119974

Published: 2018

Journal Articles

Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia

Mark C Wilkes, Jun Chen, MD PhD, Kavitha Siva, PhD, Gianluca Veretti, PhD, Daniel P. Dever, PhD, Minyoung Youn, PhD, Hee-Don Chae, PhD, Jacqueline D Mercado, Mallika Saxena, Anupama Narla, MD, Bertil Glader, MD, Matthew Porteus, MD PhD, Claire E Repellin, PhD, Hanna T Gazda, MD PhD, Manuel Serrano, PhD, Johan Flygare, MD PhD, Kathleen M. Sakamoto, MD PhD

Blood (2018) 132 (Supplement 1): 754.

https://doi.org/10.1182/blood-2018-99-119954

Published: 2018

Journal Articles

MMP9 Inhibition Rescues the Erythroid Defect in RPS14-Deficient Del(5q) MDS Models

Minyoung Youn, PhD, Haigen Huang, PhD, Cheng Chen, Sharon Kam, BS, Mark C Wilkes, Hee-Don Chae, PhD, Anupama Narla, MD, Shuo Lin, PhD, Kathleen M. Sakamoto, MD PhD

Blood (2018) 132 (Supplement 1): 756.

https://doi.org/10.1182/blood-2018-99-117508

Published: 2018

Journal Articles

Chromatin Remodeling Therapy and Capizzi Methotrexate in Treatment-Related MDS/AML

Catherine Aftandilian, MD, Kathleen M. Sakamoto, MD PhD, Kara L. Davis, DO, Gary Van Houten Dahl, MD, Norman J. Lacayo, MD

Blood (2018) 132 (Supplement 1): 5222.

https://doi.org/10.1182/blood-2018-99-110481

Published: 2018

Journal Articles

Chromatin Organization By SATB1 Regulates HSP70 Induction in Early Erythropoiesis and Lost in Diamond Blackfan Anemia

Mark C Wilkes, Kaoru Takasaki, MD, Minyoung Youn, PhD, Hee-Don Chae, PhD, Anupama Narla, MD, Kathleen M. Sakamoto, MD PhD

Blood (2018) 132 (Supplement 1): 2591.

https://doi.org/10.1182/blood-2018-99-119729

Published: 2018

Journal Articles

Nemo-like Kinase Hyper-Activated in Erythroid Progenitors in Models of Diamond Blackfan Anemia

Mark C Wilkes, Jae Wook Lee, Sriya Kudaravalli, Anupama Narla, MD, Bertil Glader, MD, Kathleen M. Sakamoto, MD PhD

Blood (2017) 130 (Supplement 1): 78.

https://doi.org/10.1182/blood.V130.Suppl_1.78.78

Published: 2017

Journal Articles

RSK Inhibition Induces Metaphase Arrest and Apoptosis in Acute Myeloid Leukemia Cells

Hee-Don Chae, PhD, Ritika Dutta, BS, Bruce Tiu, Kara L. Davis, DO, Norman J. Lacayo, MD, Kathleen M. Sakamoto, MD PhD

Blood (2017) 130 (Supplement 1): 2530.

https://doi.org/10.1182/blood.V130.Suppl_1.2530.2530

Published: 2017

Journal Articles

RSK Inhibition Suppresses AML Proliferation through Activation of DNA Damage Pathways and S Phase Arrest

Ritika Dutta, BS, Maria Castellanos, MD, Bruce Tiu, Hee-Don Chae, PhD, Kara L. Davis, DO, Kathleen M. Sakamoto, MD PhD

Blood (2016) 128 (22): 2894.

https://doi.org/10.1182/blood.V128.22.2894.2894

Published: 2016

Journal Articles

The Salicylamide Derivative, Niclosamide, Inhibits CREB Function in Acute Myeloid Leukemia Cells In Vitro and In Vivo

Hee-Don Chae, PhD, Nick Cox, PhD, Xiaohua Zhang, Jae Wook Lee, MD PhD, David Morgens, Michael C Bassik, PhD, Mark Smith, PhD, Kathleen M. Sakamoto, MD PhD

Blood (2016) 128 (22): 1647.

https://doi.org/10.1182/blood.V128.22.1647.1647

Published: 2016

Journal Articles

Role of Mir-34 Upregulation in Disruption of c-Myc, c-Myb and NOTCH Signaling in Diamond-Blackfan Anemia

Mark Wilkes, PhD, Elena Bibikova, PhD, Minyoung Youn, PhD, Alex Gia Lee, PhD, Ascia Eskin, M.S., Stanley Nelson, MD, Bertil Glader, MD PhD, Anupama Narla, MD, Kathleen M. Sakamoto, MD PhD

Blood (2016) 128 (22): 3895.

https://doi.org/10.1182/blood.V128.22.3895.3895

Published: 2016

Journal Articles

CREB Increases Chemotherapy Resistance through Regulation of the DNA Damage Repair Pathway in AML Cells

Ritika Dutta, BS, Bruce Tiu, Arya Kaul, Bryan Mitton, MDPhD, Kathleen M. Sakamoto, MD PhD

Blood (2015) 126 (23): 1390.

https://doi.org/10.1182/blood.V126.23.1390.1390

Published: 2015

Journal Articles

MiR34a Contributes to Defective Erythropoiesis in RPS19 Insufficient Hematopoietic Stem Cells

Elena Bibikova, Shuo Lin, PhD, Kathleen M Sakamoto, MD, PhD

Blood (2011) 118 (21): 2404.

https://doi.org/10.1182/blood.V118.21.2404.2404

Published: 2011

NARROW

Activated Natural Killer Cells Are Associated with Poor Clinical Prognosis in High-Risk B- and T- Cell Acute Lymphoblastic Leukemia

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Genetic Modulators of Niclosamide Sensitivity and Resistance in Acute Myeloid Leukemia

Metformin Upregulates Mir-26a to Improve Erythropoiesis in Preclinical Models of Diamond Blackfan Anemia through Suppression of Nlk Expression

SATB1 Regulates GATA1 Protein Expression in Early Hematopoiesis and Is Deregulated in Diamond Blackfan Anemia

Pp90RSK Isoforms Play Distinct Roles during Hematopoiesis

Targeting of Calbindin 1 (CALB1) Rescues Erythropoiesis in a Human Model of Diamond Blackfan Anemia: Implications for Novel Therapies

Pharmacological Inhibition of Nemo-like Kinase Rescues mTOR-Mediated Translation and Primes Progenitors for Leucine-Stimulated Erythroid Expansion in Pre-Clinical Models of Diamond Blackfan Anemia

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia

MMP9 Inhibition Rescues the Erythroid Defect in RPS14-Deficient Del(5q) MDS Models

Chromatin Remodeling Therapy and Capizzi Methotrexate in Treatment-Related MDS/AML

Chromatin Organization By SATB1 Regulates HSP70 Induction in Early Erythropoiesis and Lost in Diamond Blackfan Anemia

Nemo-like Kinase Hyper-Activated in Erythroid Progenitors in Models of Diamond Blackfan Anemia

RSK Inhibition Induces Metaphase Arrest and Apoptosis in Acute Myeloid Leukemia Cells

RSK Inhibition Suppresses AML Proliferation through Activation of DNA Damage Pathways and S Phase Arrest

The Salicylamide Derivative, Niclosamide, Inhibits CREB Function in Acute Myeloid Leukemia Cells In Vitro and In Vivo

Role of Mir-34 Upregulation in Disruption of c-Myc, c-Myb and NOTCH Signaling in Diamond-Blackfan Anemia

CREB Increases Chemotherapy Resistance through Regulation of the DNA Damage Repair Pathway in AML Cells

MiR34a Contributes to Defective Erythropoiesis in RPS19 Insufficient Hematopoietic Stem Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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