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Journal Articles

Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis

Wenqing Wang, Martin Arreola, Thomas Mathews, Andrew W DeVilbiss, Zhiyu Zhao, Misty Martin-Sandoval, Abdulvasey Mohammed, Giorgia Benegiamo, Avni Awani, Ludger J. E. Goeminne, Daniel Patrick Dever, Yusuke Nakauchi, Matthew H Porteus, Mara Pavel-Dinu, Waleed Al Herz, Johan Auwerx, Sean J. Morrison, Katja G. Weinacht

Blood blood.2024024123.

https://doi.org/10.1182/blood.2024024123

Published: 2024

Includes: Supplemental data

Journal Articles

The rise of haplo: a quest for the perfect graft

Katja G. Weinacht

Blood (2024) 143 (3): 193–195.

https://doi.org/10.1182/blood.2023022428

Published: 2024

Journal Articles

Loss of Metabolic Control Beyond the Promyelocyte Stage Resolves Myeloid Maturation Arrest in Reticular Dysgenesis

Wenqing Wang, Martin Arreola, Thomas Mathews, Andrew Devilbiss, Zhiyu Zhao, Sean Morrison, Katja G. Weinacht

Blood (2023) 142 (Supplement 1): 5576.

https://doi.org/10.1182/blood-2023-185497

Published: 2023

Journal Articles

Accelerating Immune Reconstitution in HSCT Patients through iPSC-Derived Thymic Epithelial Cells

Abdulvasey Mohammed, Hanh Dan Nguyen, Kelsea Hubka, Wenqing Wang, Priscila Slepicka, Phd, Ben Solomon, Martin Arreola, Zihao Zheng, Andrew Gentles, Katja G. Weinacht

Blood (2023) 142 (Supplement 1): 460.

https://doi.org/10.1182/blood-2023-186901

Published: 2023

Journal Articles

Functional Human iPSC-Derived Thymic Epithelial Progenitor Cells Reconstitute T Cell Development and Function in an In Vivo Model of Thymic Aplasia

Priscila Ferreira Slepicka, Phd, Kelsea M Hubka, Hanh Dan Nguyen, Abdulvasey Mohammed, Jing Wang, Casey Gifford, Vittorio Sebastiano, Katja G. Weinacht

Blood (2022) 140 (Supplement 1): 7340–7341.

https://doi.org/10.1182/blood-2022-171133

Published: 2022

Journal Articles

Reticular Dysgenesis-Associated Adenylate Kinase 2 Deficiency Impairs Purine Metabolism and Ribosomal Biogenesis during Myelopoiesis

Wenqing Wang, Andrew Devilbiss, Martin Arreola, Thomas Mathews, Misty Martin-Sandoval, Zhiyu Zhao, Avni Awani, Daniel P. Dever, Matthew H. Porteus, Sean Morrison, Katja G Weinacht

Blood (2021) 138 (Supplement 1): 3257.

https://doi.org/10.1182/blood-2021-151919

Published: 2021

Journal Articles

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-137762

Published: 2020

Journal Articles

Reticular Dysgenesis-Associated Adenylate Kinase 2 Deficiency Impairs Hematopoietic Stem and Progenitor Cell Function through Reductive Stress

Wenqing Wang, PhD, Andrew Devilbiss, PhD, Thomas Mathews, PhD, Martin Arreola, Misty Martin, Zhiyu Zhao, DPhil, Avni Awani, PhD, Daniel P. Dever, PhD, Matthew H. Porteus, MD PhD, Sean Morrison, PhD, Katja G Weinacht, MD PhD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-138560

Published: 2020

Journal Articles

Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report

Lauri M. Burroughs, Aleksandra Petrovic, Ruta Brazauskas, Xuerong Liu, Linda M. Griffith, Hans D. Ochs, Jack J. Bleesing, Stephanie Edwards, Christopher C. Dvorak, Sonali Chaudhury, Susan E. Prockop, Ralph Quinones, Frederick D. Goldman, Troy C. Quigg, Shanmuganathan Chandrakasan, Angela R. Smith, Suhag Parikh, Blachy J. Dávila Saldaña, Monica S. Thakar, Rachel Phelan, Shalini Shenoy, Lisa R. Forbes, Caridad Martinez, Deepak Chellapandian, Evan Shereck, Holly K. Miller, Neena Kapoor, Jessie L. Barnum, Hey Chong, David C. Shyr, Karin Chen, Rolla Abu-Arja, Ami J. Shah, Katja G. Weinacht, Theodore B. Moore, Avni Joshi, Kenneth B. DeSantes, Alfred P. Gillio, Geoffrey D. E. Cuvelier, Michael D. Keller, Jacob Rozmus, Troy Torgerson, Michael A. Pulsipher, Elie Haddad, Kathleen E. Sullivan, Brent R. Logan, Donald B. Kohn, Jennifer M. Puck, Luigi D. Notarangelo, Sung-Yun Pai, David J. Rawlings, Morton J. Cowan

Blood (2020) 135 (23): 2094–2105.

https://doi.org/10.1182/blood.2019002939

Published: 2020

Journal Articles

Adenylate Kinase 2 Links Energy Metabolism and Cell Fate in Hematopoietic Stem and Progenitor Cells

Wenqing Wang, PhD, Avni Awani, PhD, Andrew Devilbiss, PhD, Thomas Mathews, PhD, Daniel Thomas, MD PhD, Daniel P. Dever, PhD, Matthew Porteus, MD PhD, Sean Morrison, PhD, Katja G Weinacht, MD PhD

Blood (2019) 134 (Supplement_1): 3705.

https://doi.org/10.1182/blood-2019-129424

Published: 2019

Journal Articles

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

Hui Gai, MD, Rafa Gras~Pena, PhD, Yogendra Verma, MS, Vincent Fateh, BS, Kazuya Ikeda, MD, Beruh Dejene, MS, Dullei Min, Jing Wang, MD, Tomek Swigut, PhD, Ken I. Weinberg, MD, Georg A. Hollander, MD, Sarah Heilshorn, PhD, Maria-Grazia Roncarolo, MD, Vittorio Sebastiano, PhD, Katja G. Weinacht, MD PhD

Blood (2018) 132 (Supplement 1): 5092.

https://doi.org/10.1182/blood-2018-99-117499

Published: 2018

Journal Articles

An Engineered Cell-Traceable Model of Reticular Dysgenesis in Human Hematopoietic Stem Cells Linking Metabolism and Differentiation

Wenqing Wang, PhD, Avni Awani, PhD, Lauren Reich, Yusuke Nakauchi, MD PhD, Daniel Thomas, MD PhD, Daniel P. Dever, PhD, Matthew Porteus, MD PhD, Katja G. Weinacht, MD PhD

Blood (2018) 132 (Supplement 1): 2558.

https://doi.org/10.1182/blood-2018-99-117926

Published: 2018

Journal Articles

iPSC-Derived Thymic Epithelial Progenitor Cells As Cell-Based TherapyÂ to Restore Thymic Function in Hematopoietic Stem Cell Transplant Recipients

Hui Gai, MD, Vittorio Sebastiano, PhD, Katja G. Weinacht, MD PhD

Blood (2017) 130 (Supplement 1): 2445.

https://doi.org/10.1182/blood.V130.Suppl_1.2445.2445

Published: 2017

Journal Articles

Successful Therapy of a Patient with a Novel STAT1 Gain of Function Mutation and Life-Threatening Cytopenias with Janus Kinase Inhibitor Ruxolitinib

Katja G. Weinacht, MD PhD, Louis m Charbonnier, PhD, Ashley Plant, MD, Troy Torgerson, MD PhD, Sergei Rosenzweig, MD PhD, Thomas Fleisher, MD PhD, Luigi Daniele Notarangelo, MD

Blood (2015) 126 (23): 3434.

https://doi.org/10.1182/blood.V126.23.3434.3434

Published: 2015

Journal Articles

Linking Oxidative Stress to Cell Fate-Ipsc-Based Disease Modeling Identifies New Therapeutic Target in Reticular Dysgenesis

Katja G. Weinacht, MD PhD

Blood (2014) 124 (21): 227.

https://doi.org/10.1182/blood.V124.21.227.227

Published: 2014

Journal Articles

Induced Pluripotent Stem Cells From a Patient with Reticular Dysgenesis Recapitulate Defective Myelopoiesis in-Vitro: A Disease Model to Enhance Our Understanding of a Rare Disease.

Katja G. Weinacht, MD, PhD, Kerstin Felgentreff, MD, Alex Devine, MS, Axel Schambach, MD PhD, Waleed Al-herz, MD, Luigi Daniele Notarangelo, MD

Blood (2012) 120 (21): 2142.

https://doi.org/10.1182/blood.V120.21.2142.2142

Published: 2012

NARROW

Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis

The rise of haplo: a quest for the perfect graft

Loss of Metabolic Control Beyond the Promyelocyte Stage Resolves Myeloid Maturation Arrest in Reticular Dysgenesis

Accelerating Immune Reconstitution in HSCT Patients through iPSC-Derived Thymic Epithelial Cells

Functional Human iPSC-Derived Thymic Epithelial Progenitor Cells Reconstitute T Cell Development and Function in an In Vivo Model of Thymic Aplasia

Reticular Dysgenesis-Associated Adenylate Kinase 2 Deficiency Impairs Purine Metabolism and Ribosomal Biogenesis during Myelopoiesis

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Reticular Dysgenesis-Associated Adenylate Kinase 2 Deficiency Impairs Hematopoietic Stem and Progenitor Cell Function through Reductive Stress

Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report

Adenylate Kinase 2 Links Energy Metabolism and Cell Fate in Hematopoietic Stem and Progenitor Cells

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

An Engineered Cell-Traceable Model of Reticular Dysgenesis in Human Hematopoietic Stem Cells Linking Metabolism and Differentiation

iPSC-Derived Thymic Epithelial Progenitor Cells As Cell-Based TherapyÂ to Restore Thymic Function in Hematopoietic Stem Cell Transplant Recipients

Successful Therapy of a Patient with a Novel STAT1 Gain of Function Mutation and Life-Threatening Cytopenias with Janus Kinase Inhibitor Ruxolitinib

Linking Oxidative Stress to Cell Fate-Ipsc-Based Disease Modeling Identifies New Therapeutic Target in Reticular Dysgenesis

Induced Pluripotent Stem Cells From a Patient with Reticular Dysgenesis Recapitulate Defective Myelopoiesis in-Vitro: A Disease Model to Enhance Our Understanding of a Rare Disease.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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