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Journal Articles

Total Proteome Analysis Identifies Migration Defects As a Major Pathogenetic Factor in IGHV-Unmutated Chronic Lymphocytic Leukemia

Gina L Eagle, PhD, Rosalind E Jenkins, PhD, Kathleen J Till, PhD, Jithesh Puthen, PhD, Ke Lin, PhD, Gillian G Johnson, PhD, Melanie Oates, PhD, Kevin Park, PhD, Neil R Kitteringham, PhD, Jianguo Zhuang, PhD, Andrew R Pettitt, MRCP, PhD

Blood (2014) 124 (21): 718.

https://doi.org/10.1182/blood.V124.21.718.718

Published: 2014

Journal Articles

A Complementary Role of High Throughput Sequencing and Multiparameter Cytometry for Minimal Residual Disease (MRD) Detection in Chronic Lymphocytic Leukemia (CLL):an European Research Initiative (ERIC) Study

Andy Rawstron, PhD, Claudia Fazi, PhD, Neus Villamor, MD PhD, Julio Delgado, MD PhD, Remi Letestu, MD PhD, Florence Cymbalista, MD, Carlos Palacio, Francesc Bosch, MD PhD, Ruth M De Tute, MSc, Stuart Liptrot, David O'Brien, FAMLs, Martin Spacek, MD, PhD, Johan Dobber, Arnon P. Kater, MD PhD, Peter C Gambell, David A Westerman, MBBS, FRACP, FRCPA, Asha Soosapilla, Stephen P. Mulligan, MBBS, PhD FRACP, FRCPA, Gerard Lozanski, MD, Ke Lin, PhD, Andrew R Pettitt, MRCP, PhD, Gabi Brachtl, Alexander Egle, MD, David W Williamson, PhD, Catherine M Sanders, PhD, Harlan Robins, PhD, Justin Boysen, Tait D. Shanafelt, MD, Curtis A. Hanson, MD, Jeffrey L. Jorgensen, MD PhD, William G. Wierda, MD PhD, Constance Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Laura Rassenti, PhD, H. Elizabeth Broome, MD, Thomas J. Kipps, MD PhD, Mathieu Hauwel, Iuri Marinov, Fiona E. Craig, MBBS, Nomdedeu Josep, Carol Moreno, MD, Olga Stehlikova, MSc., Michael Doubek, Sarka Pospisilova, Prof., Dr., PhD, Karl-Anton Kreuzer, MD, Michael Hallek, MD, Peter Hillmen, MBChB, PhD, Emili Montserrat, MD PhD, Paolo Ghia, MD

Blood (2014) 124 (21): 1976.

https://doi.org/10.1182/blood.V124.21.1976.1976

Published: 2014

Journal Articles

CYP2B6*6 is an independent determinant of inferior response to fludarabine plus cyclophosphamide in chronic lymphocytic leukemia

Gillian G. Johnson, Ke Lin, Trevor F. Cox, Melanie Oates, David R. Sibson, Richard Eccles, Bryony Lloyd, Laura-Jayne Gardiner, Daniel F. Carr, Munir Pirmohamed, Jonathan C. Strefford, David G. Oscier, David Gonzalez de Castro, Monica Else, Daniel Catovsky, Andrew R. Pettitt

Blood (2013) 122 (26): 4253–4258.

https://doi.org/10.1182/blood-2013-07-516666

Published: 2013

Includes: Supplemental data

Journal Articles

c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells

John C. Allen, Fatima Talab, Mirko Zuzel, Ke Lin, Joseph R. Slupsky

Blood (2011) 117 (8): 2414–2422.

https://doi.org/10.1182/blood-2010-08-301176

Published: 2011

Includes: Supplemental data

Journal Articles

C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukaemia Cells

John C Allen, Mirko Zuzel, Ke Lin, Joseph R Slupsky

Blood (2010) 116 (21): 3579.

https://doi.org/10.1182/blood.V116.21.3579.3579

Published: 2010

Journal Articles

Characterisation of B Cell Receptor-Induced NF-KB Activation In Chronic Lymphocytic Leukaemia Cells

Fatima Talab, Victoria Thompson, John C Allen, Ke Lin, Joseph R Slupsky

Blood (2010) 116 (21): 375.

https://doi.org/10.1182/blood.V116.21.375.375

Published: 2010

Journal Articles

TP53 Abnormalities in Chronic Lymphocytic Leukemia Exhibit a Disease Specific Profile: Meta-Analysis of 270 Mutations.

Blood (2008) 112 (11): 2077.

https://doi.org/10.1182/blood.V112.11.2077.2077

Published: 2008

Journal Articles

B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CβII

Simon T. Abrams, Tasneem Lakum, Ke Lin, Gemma M. Jones, Andrew T. Treweeke, Mosavar Farahani, Mair Hughes, Mirko Zuzel, Joseph R. Slupsky

Blood (2006) 109 (3): 1193–1201.

https://doi.org/10.1182/blood-2006-03-012021

Published: 2006

Includes: Supplemental data

Journal Articles

Chronic Lymphocytic Leukaemia Patients with a Biallelic Deletion of 13q14 Have a More Favourable Profile of Prognostic Factors Compared with Cases That Have a Monoallelic 13q14 Deletion.

Andrew R. Pettitt, PhD, MRCPath, Chloe J. Emmens, Ke Lin, PhD, Robert J. Harris, PhD

Blood (2005) 106 (11): 5019.

https://doi.org/10.1182/blood.V106.11.5019.5019

Published: 2005

Journal Articles

Over-Expression of c-Abl in CLL Cells Is Associated with Advanced Disease, and Contributes to CLL-Cell Survival through Activation of NF-kB.

Ke Lin, PhD, Robert J. Harris, PhD, Sally Dennett, John C. Cawley, MD, PhD, Mirko Zuzel, MD, Joseph R. Slupsky, PhD

Blood (2005) 106 (11): 1191.

https://doi.org/10.1182/blood.V106.11.1191.1191

Published: 2005

Journal Articles

Proteomic Analysis of CLL-Cell Lipid Rafts Reveals Differential Expression of Raft-Associated ATP Synthase.

David Allsup, PhD, Ke Lin, PhD, Caroline Evans, PhD, John C. Cawley, PhD, Mirko Zuzel, PhD, Burthem John, PhD

Blood (2004) 104 (11): 179.

https://doi.org/10.1182/blood.V104.11.179.179

Published: 2004

Journal Articles

Associations between Chromosomal Aberrations and Functional Impairment of the P53 Pathway in Chronic Lymphocytic Leukaemia.

Andrew R. Pettitt, Anthony Carter, Ke Lin, Paul D. Sherrington, Mark Atherton, Kevin Pearson, Angela Douglas, Anna Burford, V. Brito-Babapulle, Estella Matutes, Daniel Catovsky

Blood (2004) 104 (11): 953.

https://doi.org/10.1182/blood.V104.11.953.953

Published: 2004

Journal Articles

High frequency of p53 dysfunction and low level of V H mutation in chronic lymphocytic leukemia patients using the V H 3-21 gene segment

Ke Lin, Sameer Manocha, Robert J. Harris, Zoltan Matrai, Paul D. Sherrington, Andrew R. Pettitt

Blood (2003) 102 (3): 1145–1146.

https://doi.org/10.1182/blood-2003-04-1289

Published: 2003

Journal Articles

Relationship between p53 dysfunction, CD38 expression, and IgV H mutation in chronic lymphocytic leukemia

Ke Lin, Paul D. Sherrington, Michael Dennis, Zoltan Matrai, John C. Cawley, Andrew R. Pettitt

Blood (2002) 100 (4): 1404–1409.

https://doi.org/10.1182/blood-2001-11-0066

Published: 2002

Journal Articles

The chemokine receptor CCR7 and α4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

Kathleen J. Till, Ke Lin, Mirko Zuzel, John C. Cawley

Blood (2002) 99 (8): 2977–2984.

https://doi.org/10.1182/blood.V99.8.2977

Published: 2002

Journal Articles

CD38 expression and Ig V H gene mutation in B-cell chronic lymphocytic leukemia

Zoltan Matrai, Ke Lin, Michael Dennis, Paul Sherrington, Mirko Zuzel, Andrew R Pettitt, John C. Cawley

Blood (2001) 97 (6): 1902.

https://doi.org/10.1182/blood.V97.6.1902

Published: 2001

NARROW

Total Proteome Analysis Identifies Migration Defects As a Major Pathogenetic Factor in IGHV-Unmutated Chronic Lymphocytic Leukemia

A Complementary Role of High Throughput Sequencing and Multiparameter Cytometry for Minimal Residual Disease (MRD) Detection in Chronic Lymphocytic Leukemia (CLL):an European Research Initiative (ERIC) Study

CYP2B6*6 is an independent determinant of inferior response to fludarabine plus cyclophosphamide in chronic lymphocytic leukemia

c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells

C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukaemia Cells

Characterisation of B Cell Receptor-Induced NF-KB Activation In Chronic Lymphocytic Leukaemia Cells

TP53 Abnormalities in Chronic Lymphocytic Leukemia Exhibit a Disease Specific Profile: Meta-Analysis of 270 Mutations.

B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CβII

Chronic Lymphocytic Leukaemia Patients with a Biallelic Deletion of 13q14 Have a More Favourable Profile of Prognostic Factors Compared with Cases That Have a Monoallelic 13q14 Deletion.

Over-Expression of c-Abl in CLL Cells Is Associated with Advanced Disease, and Contributes to CLL-Cell Survival through Activation of NF-kB.

Proteomic Analysis of CLL-Cell Lipid Rafts Reveals Differential Expression of Raft-Associated ATP Synthase.

Associations between Chromosomal Aberrations and Functional Impairment of the P53 Pathway in Chronic Lymphocytic Leukaemia.

High frequency of p53 dysfunction and low level of V H mutation in chronic lymphocytic leukemia patients using the V H 3-21 gene segment

Relationship between p53 dysfunction, CD38 expression, and IgV H mutation in chronic lymphocytic leukemia

The chemokine receptor CCR7 and α4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

CD38 expression and Ig V H gene mutation in B-cell chronic lymphocytic leukemia

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American Society of Hematology

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American Society of Hematology

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