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Munir Pirmohamed
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Journal Articles

CYP2B6*6 is an independent determinant of inferior response to fludarabine plus cyclophosphamide in chronic lymphocytic leukemia

Gillian G. Johnson, Ke Lin, Trevor F. Cox, Melanie Oates, David R. Sibson, Richard Eccles, Bryony Lloyd, Laura-Jayne Gardiner, Daniel F. Carr, Munir Pirmohamed, Jonathan C. Strefford, David G. Oscier, David Gonzalez de Castro, Monica Else, Daniel Catovsky, Andrew R. Pettitt
Journal: Blood
Blood (2013) 122 (26): 4253–4258.
https://doi.org/10.1182/blood-2013-07-516666
Published: 2013
Includes: Supplemental data
Journal Articles

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

Athina Giannoudis, Lihui Wang, Andrea L. Jorgensen, George Xinarianos, Andrea Davies, Sudeep Pushpakom, Triantafilos Liloglou, Jieying-Eunice Zhang, Gemma Austin, Tessa L. Holyoake, Letizia Foroni, Panagiotis D. Kottaridis, Martin C. Müller, Munir Pirmohamed, Richard E. Clark
Journal: Blood
Blood (2013) 121 (4): 628–637.
https://doi.org/10.1182/blood-2012-01-405035
Published: 2013
Includes: Supplemental data
Journal Articles

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

Nita A. Limdi, Mia Wadelius, Larisa Cavallari, Niclas Eriksson, Dana C. Crawford, Ming-Ta M. Lee, Chien-Hsiun Chen, Alison Motsinger-Reif, Hersh Sagreiya, Nianjun Liu, Alan H. B. Wu, Brian F. Gage, Andrea Jorgensen, Munir Pirmohamed, Jae-Gook Shin, Guilherme Suarez-Kurtz, Stephen E. Kimmel, Julie A. Johnson, Teri E. Klein, Michael J. Wagner
Journal: Blood
Blood (2010) 115 (18): 3827–3834.
https://doi.org/10.1182/blood-2009-12-255992
Published: 2010
Includes: Supplemental data
Journal Articles

Nilotinib concentration in Cell Lines and CML CD34+ Cells Is Not Mediated by Active Uptake or Efflux by Major Drug Transporters

Joanne Mountford, PhD, Andrea Davies, Niove E Jordanides, Athina Giannoudis, Claire M Lucas, Sophia Hatziieremia, Robert J Harris, Heather G Jorgensen, Munir Pirmohamed, Tessa L Holyoake, Richard E Clark
Journal: Blood
Blood (2008) 112 (11): 3205.
https://doi.org/10.1182/blood.V112.11.3205.3205
Published: 2008
Journal Articles

Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia

Athina Giannoudis, Andrea Davies, Claire M. Lucas, Robert J. Harris, Munir Pirmohamed, Richard E. Clark
Journal: Blood
Blood (2008) 112 (8): 3348–3354.
https://doi.org/10.1182/blood-2007-10-116236
Published: 2008
Journal Articles

Characterisation of Nilotinib Transport in Chronic Myeloid Leukaemia Cells.

Andrea Davies, PhD, Athina Giannoudis, PhD, Claire M. Lucas, BSc, Robert J. Harris, PhD, Paul W. Manley, PhD, Munir Pirmohamed, PhD, FRCP, FRCP(E), Richard E. Clark, MA, MD, FRCP, FRCPat
Journal: Blood
Blood (2007) 110 (11): 2364.
https://doi.org/10.1182/blood.V110.11.2364.2364
Published: 2007
Journal Articles

Unlike Imatinib, Dasatinib Uptake into Chronic Myeloid Leukaemia Cells Is Independent of hOCT1 Expression.

Athina Giannoudis, PhD, Andrea Davies, PhD, Claire M. Lucas, BSc, Robert J. Harris, PhD, Munir Pirmohamed, PhD, FRCP, FRCP(E), Richard E. Clark, MA, MD, FRCP, FRCPat
Journal: Blood
Blood (2007) 110 (11): 3458.
https://doi.org/10.1182/blood.V110.11.3458.3458
Published: 2007
Journal Articles

Clinical and Functional Evidence That Drug Transporter Expression Dictates the Response to Imatinib in Chronic Myeloid Leukaemia.

Lihui Wang, MD, Athina Giannoudis, PhD, Steven Lane, PhD, Paula R. Williamson, PhD, Munir Pirmohamed, PhD, Richard E. Clark, MD
Journal: Blood
Blood (2006) 108 (11): 2145.
https://doi.org/10.1182/blood.V108.11.2145.2145
Published: 2006
Journal Articles

Active transport of imatinib into and out of cells: implications for drug resistance

Julia Thomas, Lihui Wang, Richard E. Clark, Munir Pirmohamed
Journal: Blood
Blood (2004) 104 (12): 3739–3745.
https://doi.org/10.1182/blood-2003-12-4276
Published: 2004