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Keiko Akagi
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Journal Articles

Single Cell Multi-Omic Analysis of Neoplastic Plasma Cells across the Disease Spectrum Identifies Novel Pathobiologic Mediators and Potential Therapeutic Targets in Multiple Myeloma (MM)

Luz Yurany Moreno Rueda, Keiko Akagi, Amishi U. Vora, Hans C. Lee, Krina K. Patel, Pei Lin, Bo Jiang, Yang Song, Maura L. Gillison, Sheeba K. Thomas, Donna M. Weber, Lixia Diao, Jing Wang, Elisabet E. Manasanch, David E. Symer, Robert Z. Orlowski
Journal: Blood
Blood (2023) 142 (Supplement 1): 752.
https://doi.org/10.1182/blood-2023-188016
Published: 2023
Journal Articles

Preclinical Testing Of a PI3K Inhibitor In T Lineage Leukemia: Target Validation and Notch1/Myc Down-Regulation In Drug Resistant Clones

Monique Dail, PhD, Jason Wong, Jessica Lawrence, Daniel O'Connor, Joy Nakitandwe, PhD., Shann-Ching Chen, PhD, Keiko Akagi, Leslie Lee, Jon C. Aster, MD, PhD, Warren S. Pear, MD, PhD, Deepak Sampath, PhD, James R. Downing, MD, Kevin Shannon, MD
Journal: Blood
Blood (2013) 122 (21): 2677.
https://doi.org/10.1182/blood.V122.21.2677.2677
Published: 2013
Journal Articles

Hematopoiesis and leukemogenesis in mice expressing oncogenic Nras G12D from the endogenous locus

Qing Li, Kevin M. Haigis, Andrew McDaniel, Emily Harding-Theobald, Scott C. Kogan, Keiko Akagi, Jasmine C. Y. Wong, Benjamin S. Braun, Linda Wolff, Tyler Jacks, Kevin Shannon
Journal: Blood
Blood (2011) 117 (6): 2022–2032.
https://doi.org/10.1182/blood-2010-04-280750
Published: 2011
Includes: Supplemental data
Journal Articles

Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies

Jasmine C. Y. Wong, Yan Zhang, Kenneth H. Lieuw, Mary T. Tran, Erna Forgo, Kelley Weinfurtner, Pilar Alzamora, Scott C. Kogan, Keiko Akagi, Linda Wolff, Michelle M. Le Beau, Nigel Killeen, Kevin Shannon
Journal: Blood
Blood (2010) 115 (22): 4524–4532.
https://doi.org/10.1182/blood-2009-07-232504
Published: 2010
Includes: Supplemental data
Journal Articles

Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector–transduced CD34 + cells

Yoo-Jin Kim, Yoon-Sang Kim, Andre Larochelle, Gabriel Renaud, Tyra G. Wolfsberg, Rima Adler, Robert E. Donahue, Peiman Hematti, Bum-Kee Hong, Jean Roayaei, Keiko Akagi, Janice M. Riberdy, Arthur W. Nienhuis, Cynthia E. Dunbar, Derek A. Persons
Journal: Blood
Blood (2009) 113 (22): 5434–5443.
https://doi.org/10.1182/blood-2008-10-185199
Published: 2009
Includes: Supplemental data
Journal Articles

Murine Leukemias with Insertional Mutations at Lmo2 Are Highly Predicitive of Leukemias Induced Following Gene Therapy in SCID-X1 Patients

Utpal P. Dave, MD, Keiko Akagi, Ph.D., Rati Tripathi, Susan Cleveland, Mary Thompson, Ming Yi, PhD., Robert Stephens, James R. Downing, MD, Nancy Jenkins, PhD., Neal G. Copeland, PhD.
Journal: Blood
Blood (2008) 112 (11): 4629.
https://doi.org/10.1182/blood.V112.11.4629.4629
Published: 2008
Journal Articles

Kras G12D Expression in Hematopoietic Stem/Progenitor Cells Initiates T Cell Acute Lymphoblastic Leukemia/Lymphoma.

Monique Dail, PhD, Qing Li, MD, PhD, Jennifer Lauchle, MD, Andrew McDaniel, Doris Kim, Keiko Akagi, PhD, Linda Wolff, PhD, Nancy Jenkins, PhD, Neil Copeland, PhD, Kevin Shannon, MD
Journal: Blood
Blood (2007) 110 (11): 153.
https://doi.org/10.1182/blood.V110.11.153.153
Published: 2007
Journal Articles

Mutations That Cooperate with Nf1 Inactivation in Leukemogenesis Influence Therapeutic Response to MEK Inhibition.

Jennifer O. Lauchle, MD, Doan T. Le, MD, Doris Kim, Keiko Akagi, PhD, Matthew F. Gorman, MD, Mary Tran, Judith Sebolt-Leopold, PhD, Linda Wolff, PhD, Luis F. Parada, PhD, Nancy Jenkins, PhD, Neal Copeland, PhD, Kevin M. Shannon, MD
Journal: Blood
Blood (2007) 110 (11): 594.
https://doi.org/10.1182/blood.V110.11.594.594
Published: 2007
Journal Articles

Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells

Brief Report
Boris Calmels, Cole Ferguson, Mikko O. Laukkanen, Rima Adler, Marion Faulhaber, Hyeoung-Joon Kim, Stephanie Sellers, Peiman Hematti, Manfred Schmidt, Christof von Kalle, Keiko Akagi, Robert E. Donahue, Cynthia E. Dunbar
Journal: Blood
Blood (2005) 106 (7): 2530–2533.
https://doi.org/10.1182/blood-2005-03-1115
Published: 2005
Includes: Supplemental data
Journal Articles

Proviral Tagging Combined with Human Microarray Data Reveals Genes and Pathways That Cooperate in Disease Induction.

Utpal P. Dave, M.D., Keiko Akagi, Ph.D., Adam Dupuy, Ph.D., Takeshi Suzuki, Ph.D., Nancy A. Jenkins, Ph.D., Neal G. Copeland, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 3492.
https://doi.org/10.1182/blood.V104.11.3492.3492
Published: 2004
Journal Articles

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein

Søren Warming, Pentao Liu, Takeshi Suzuki, Keiko Akagi, Susan Lindtner, George N. Pavlakis, Nancy A. Jenkins, Neal G. Copeland
Journal: Blood
Blood (2003) 101 (5): 1934–1940.
https://doi.org/10.1182/blood-2002-08-2652
Published: 2003