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Journal Articles

Concomitant Targeting Aggresome Formation and Intracellar Proteolytic Pathways Enhances ER-Stress Mediated Cell Death In Myeloma Cells

Shota Moriya, Xiao-Fang Che, MD, PhD, Seiichiro Komatsu, MD, Keisuke Miyazawa, MD, PhD

Blood (2013) 122 (21): 4910.

https://doi.org/10.1182/blood.V122.21.4910.4910

Published: 2013

Journal Articles

Macrolide Antibiotics Block Autophagy Flux and Sensitize to Bortezomib Via Endoplasmic Reticulum-Stress-Mediated CHOP Induction in Myeloma Cells

Shota Moriya, Xiao-Fang Che, MD, PhD, Seiichiro Komatsu, MD, Akihisa Abe, PhD, Tomohiro Kawaguchi, Akihiko Gotoh, MD, PhD, Masato Inazu, PhD, Akio Tomoda, MD, PhD, Keisuke Miyazawa, MD, PhD

Blood (2012) 120 (21): 4992.

https://doi.org/10.1182/blood.V120.21.4992.4992

Published: 2012

Journal Articles

Combined Treatment with Bortezomib Plus Bafilomycin A 1 Enhances Cytocidal Effect along with Induction of ER Stress In Myeloma Cells: Crosstalk Among Proteasome, Autophagy-Lysosome, and ER Stress

Keisuke Miyazawa, MD, PhD, Shota Moriya, Tomohiro Kawaguchi, Tadashi Ohtomo, Xiao-Fang Che, MD, PhD, Munekazu Naito, MD., PhD, Masahiro Itoh, MD, PhD, Akio Tomoda

Blood (2010) 116 (21): 4058.

https://doi.org/10.1182/blood.V116.21.4058.4058

Published: 2010

Journal Articles

Cytoprotective Autophagy Induction by Imatinib Mesylate In Non-BCR-ABL Expressing Cells

Keisuke Miyazawa, MD, PhD, Tadashi Ohtomo, Shota Moriya, Munekazu Naito, MD, PhD, Masahiko Kuroda, MD, PhD, Masahiro Itoh, MD, PhD, Akio Tomoda, MD, PhD

Blood (2010) 116 (21): 4937.

https://doi.org/10.1182/blood.V116.21.4937.4937

Published: 2010

Journal Articles

Vitamin K2 Induces Autophagy and Apoptosis Simultaneously in Leukemia Cells and Bcl-2 Expression Level Determines the Phenotype of Their Cell Death.

Keisuke Miyazawa, MD, Tomohisa Yokoyama, MD, Munekazu Naito, MD, Juri Toyotake, MD, Testuzo Tauchi, MD, Masahiro Itoh, MD, Akira Yuo, MD, Yasuko Kondo, MD, Seiji Kondo, MD, Kazuma Ohyashiki, MD

Blood (2007) 110 (11): 3478.

https://doi.org/10.1182/blood.V110.11.3478.3478

Published: 2007

Journal Articles

Autophagy Induction of Acute Myeloid Leukemia (AML) Cells after Treatment with Low Dose-Cytarabine (Ara-C) and Enhanced Cytocidal Effect on AML Cells by Combined Treatment with Ara-C Plus Lenograstim.

Keisuke Miyazawa, MD, Juri Toyotake, MD, Munekazu Naito, MD, Masahiro Itoh, MD, Kazuma Ohyashiki, MD

Blood (2007) 110 (11): 4185.

https://doi.org/10.1182/blood.V110.11.4185.4185

Published: 2007

Journal Articles

Autophagy and Apoptosis Are Induced Simultaneously in Leukemia Cells by Vitamin K2.

Keisuke Miyazawa, MD, PhD, Tomohisa Yokoyama, MD, PhD, Juri Toyotake, MD, Akihiko Gotoh, MD, PhD, Munekazu Naito, MD, PhD, Masahiro Ito, MD, PhD, Akira Yuo, MD, PhD, Seiji Kondo, MD, PhD, Kazuma Ohyashiki, MD, PhD

Blood (2006) 108 (11): 4373.

https://doi.org/10.1182/blood.V108.11.4373.4373

Published: 2006

Journal Articles

Clinical Analysis of Adult Acute Leukemia with Rearrangements of the 11q23/MLL: Multicenter Co-Operative Study.

Blood (2006) 108 (11): 2354.

https://doi.org/10.1182/blood.V108.11.2354.2354

Published: 2006

Journal Articles

Myelodysplastic Syndromes with Myelofibrosis May Be a Target for the JAK2 V617F Tyrosine Kinase Mutation.

Kazuma Ohyashiki, MD, Yasuo Aota, MD, Akihiko Gotoh, MD, Keisuke Miyazawa, MD, Yukihiko Kimura, MD, Junko H. Ohyashiki, MD

Blood (2005) 106 (11): 4895.

https://doi.org/10.1182/blood.V106.11.4895.4895

Published: 2005

Journal Articles

Vitamin K2 (VK2) Monotherapy and VK2 Plus D3 Combination Therapy in Low-Risk Myelodysplastic Syndrome: A Prospective Japanese Study.

Keisuke Miyazawa, MD, Kazuma Ohyashiki, MD, Nobu Akiyama, MD, Yoshinobu Kanda, MD, Kaoru Tohyama, MD, Mistuhiro Omine, MD, Kinuko Mitani, MD

Blood (2005) 106 (11): 2528.

https://doi.org/10.1182/blood.V106.11.2528.2528

Published: 2005

Journal Articles

Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines

Younghee Lee, Akihiko Gotoh, Hyung-Joo Kwon, Minute You, Lisa Kohli, Charlie Mantel, Scott Cooper, Giao Hangoc, Keisuke Miyazawa, Kazuma Ohyashiki, Hal E. Broxmeyer

Blood (2002) 99 (12): 4307–4317.

https://doi.org/10.1182/blood.V99.12.4307

Published: 2002

NARROW

Concomitant Targeting Aggresome Formation and Intracellar Proteolytic Pathways Enhances ER-Stress Mediated Cell Death In Myeloma Cells

Macrolide Antibiotics Block Autophagy Flux and Sensitize to Bortezomib Via Endoplasmic Reticulum-Stress-Mediated CHOP Induction in Myeloma Cells

Combined Treatment with Bortezomib Plus Bafilomycin A 1 Enhances Cytocidal Effect along with Induction of ER Stress In Myeloma Cells: Crosstalk Among Proteasome, Autophagy-Lysosome, and ER Stress

Cytoprotective Autophagy Induction by Imatinib Mesylate In Non-BCR-ABL Expressing Cells

Vitamin K2 Induces Autophagy and Apoptosis Simultaneously in Leukemia Cells and Bcl-2 Expression Level Determines the Phenotype of Their Cell Death.

Autophagy Induction of Acute Myeloid Leukemia (AML) Cells after Treatment with Low Dose-Cytarabine (Ara-C) and Enhanced Cytocidal Effect on AML Cells by Combined Treatment with Ara-C Plus Lenograstim.

Autophagy and Apoptosis Are Induced Simultaneously in Leukemia Cells by Vitamin K2.

Clinical Analysis of Adult Acute Leukemia with Rearrangements of the 11q23/MLL: Multicenter Co-Operative Study.

Myelodysplastic Syndromes with Myelofibrosis May Be a Target for the JAK2 V617F Tyrosine Kinase Mutation.

Vitamin K2 (VK2) Monotherapy and VK2 Plus D3 Combination Therapy in Low-Risk Myelodysplastic Syndrome: A Prospective Japanese Study.

Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines

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American Society of Hematology

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American Society of Hematology

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