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Journal Articles

High Risk Genomic Alterations Identified at the Time of Diagnosis Are Strongly Associated with MRD and Subsequent Poor Outcomes in AYA ALL Patients Treated on a Pediatric Inspired Chemotherapy Regimen

David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Matthew Greenwood, MBBS, FRACP, FRCPA, Jacqueline Rhen, BSc MSc MD, Susan L Heatley, PhD MD, Barbara McClure, BSc (Hons) PhD, Laura N Eadie, BSc (Hons) PhD, Jimmy Breen, BSc (Hons) PhD, Caitlin Schutz Schutz, BSc (Hons), Toby N Trahair, MBBS FRACP PhD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, Luciano Dalla-Pozza, MBBS FRACP, Rosemary Sutton, BSc MSc PhD, Kenneth F Bradstock, BSc(MD, MBBS, PhD FRACP, FRCPA, Michael Philip Osborn, MB, BS, Deborah L. White, PhD FFSc (RCPA)

Blood (2019) 134 (Supplement_1): 3949.

https://doi.org/10.1182/blood-2019-127788

Published: 2019

Journal Articles

High-Annealing-Temperature PCR (HAT-PCR) Enables Sensitive Quantification of Minimal Residual Disease (MRD) in Blood in Acute Lymphoblastic Leukaemia (ALL)

Alexander A Morley, MD, Sue Latham, BSc, Elizabeth Hughes, BSc, Bradley Budgen, BSc, Matthew Greenwood, FRACP, FRCPA, Kenneth F Bradstock, Luciano Dalla-Pozza, MBBS FRACP, Tamara Law, PhD, Louise Doculara, BSc, Nicola Venn, BSc, Rosemary Sutton, PhD

Blood (2018) 132 (Supplement 1): 2831.

https://doi.org/10.1182/blood-2018-99-110123

Published: 2018

Journal Articles

Improved Concordance of Minimal Residual Disease Measurements By Quantitative PCR and 10-Color Flow Cytometry in Pediatric Acute Lymphoblastic Leukemia

Mary Sartor, PhD, Draga Barbaric, MBBS, Tamara Law, BSc (Hons), DR Anuruddhika Dissanayake, PhD, Nicola C Venn, Mawar Karsa, BSc (Hons), MSc, Sue W J Wong, BSc, MSc(MD, Murray D Norris, PhD, Tamas Revesz, MD PhD, Petra Ritchie, MBBS, Peter J Shaw, Kenneth F Bradstock, MBBS PhDFRACP FRCPA, Luciano Dalla Pozza, MBBS, FRACP, Toby N Trahair, PhD MBBS, Rosemary Sutton, PhD

Blood (2015) 126 (23): 2614.

https://doi.org/10.1182/blood.V126.23.2614.2614

Published: 2015

Journal Articles

Alterations in the Cell Cycle of Acute Lymphoblastic Leukemia Cells Resistant to Everolimus

Jordan Basnett, BSc(Hons), Eve Diefenbach, PhD, Kenneth F Bradstock, MBBS PhDFRACP FRCPA, Linda J. Bendall, BSc, PhD

Blood (2014) 124 (21): 3640.

https://doi.org/10.1182/blood.V124.21.3640.3640

Published: 2014

Journal Articles

Final Analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) APML4 Trial: All- Trans Retinoic Acid (ATRA), Intravenous Arsenic Trioxide (ATO) and Idarubicin (IDA) As Initial Therapy for Acute Promyelocytic Leukemia (APL)

Harry J Iland, MBBS FRACP FRCPA, Marnie Collins, BCom BSc(Hons), Mark S Hertzberg, MBBS PhDFRACP FRCPA, Michael Seldon, MBBS FRACP FRCPA, Andrew P Grigg, MBBS FRACP FRCPA MD, Frank Firkin, MBBS PhDFRACP FRCPA, Shane G Supple, BSc(Hons) PhD, Lynda J Campbell, Kenneth F Bradstock, MBBS PhDFRACP FRCPA, John F Seymour, MBBS, FRACP, PhD

Blood (2014) 124 (21): 375.

https://doi.org/10.1182/blood.V124.21.375.375

Published: 2014

Journal Articles

Evaluation Of Sphingosine Kinase 1 As a Therapeutic Target In B-Lineage Acute Lymphoblastic Leukemia

Craig T Wallington-Beddoe, BSc, MBBS, PhD, FRACP, FRCPA, Stuart M Pitson, BAppSc, PhD, Jason A Powell, BSc, PhD, Kenneth F Bradstock, MBBS, PhD, FRACP, FRCPA, Linda J Bendall, BSc, PhD

Blood (2013) 122 (21): 1426.

https://doi.org/10.1182/blood.V122.21.1426.1426

Published: 2013

Journal Articles

Thalidomide Consolidation Post Autologous Stem Cell Transplant (ASCT) For Multiple Myeloma (MM) Is Cost-Effective With Durable Survival Benefit At 5 Years Post Randomisation: Final Analysis Of The ALLG MM6 Study

Anna Kalff, MBBS, FRACP, FRCPA, Nola Kennedy, Angela Smiley, H. Miles Prince, MBBS, FRACP, FRCPA, MD, Andrew W. Roberts, MBBS, PhD, Kenneth F Bradstock, MBBS, PhD, FRACP, FRCPA, Richard De Abreu Lourenco, Andrew Spencer, MD

Blood (2013) 122 (21): 537.

https://doi.org/10.1182/blood.V122.21.537.537

Published: 2013

Journal Articles

Identification of Sphingosine Kinases As Therapeutic Targets in B-Lineage Acute Lymphoblastic Leukemia

Craig T Wallington-Beddoe, BSc, MB BS, FRACP, FRCPA, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, Linda J Bendall, BSc, PhD

Blood (2012) 120 (21): 1499.

https://doi.org/10.1182/blood.V120.21.1499.1499

Published: 2012

Journal Articles

Effects of G-CSF On Acute Lymphoblastic Leukemia.

Jordan Basnett, BSc(Hons), Adam Cisterne, BSc(Hons), Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, Linda J Bendall, BSc, PhD

Blood (2012) 120 (21): 2564.

https://doi.org/10.1182/blood.V120.21.2564.2564

Published: 2012

Journal Articles

Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice

Julius G. Juarez, Nadia Harun, Marilyn Thien, Robert Welschinger, Rana Baraz, Aileen Dela Pena, Stuart M. Pitson, Michael Rettig, John F. DiPersio, Kenneth F. Bradstock, Linda J. Bendall

Blood (2012) 119 (3): 707–716.

https://doi.org/10.1182/blood-2011-04-348904

Published: 2012

Includes: Supplemental data

Journal Articles

Upregulation of the Chemokine Receptor CCR5 on CD16+ Myeloid Blood Dendritic Cells in Allogeneic Hemopoietic Cell Transplant Patients Predicts for Acute Graft Versus Host Disease

Kifah Shahin, PhD, Mary M Sartor, BSc, MSc, Derek NJ Hart, MBCHB, DPhil, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA

Blood (2011) 118 (21): 1982.

https://doi.org/10.1182/blood.V118.21.1982.1982

Published: 2011

Journal Articles

Increased Production of the Inflammatory Cytokine IL12p70 by Activated Human Blood Dendritic Cells Is Associated with Increased Severity of Acute Graft Vs Host Disease Post Allogeneic Hemopoietic Cell Transplantation

Mary M Sartor, BSc, MSc, Jenny Lau, PhD, David Gottlieb, MB, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA

Blood (2011) 118 (21): 4539.

https://doi.org/10.1182/blood.V118.21.4539.4539

Published: 2011

Journal Articles

Factors Predicting the Outcome of the Blood and Marrow Transplant Patients Admitted to Intensive Care Unit.

Nalini K Pati, Biju George, Ian Kerridge, Nicole Gilroy, Vineet Nayyar, Eddie Stachowski, Mary McGurgan, Gillian Huang, Kenneth F Bradstock, David J Gottlieb, Mark Hertzberg

Blood (2009) 114 (22): 3340.

https://doi.org/10.1182/blood.V114.22.3340.3340

Published: 2009

Journal Articles

Combining RAD001 (Everolimus) with Proteasome Inhibitors Bortezomib (Velcade) or MG132 Significantly Enhances Pre-B ALL Cell Death in Vitro.

Philip O. Saunders, MB, MRCP, FRACP, FRCPA, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, Linda J. Bendall, BSc, PhD

Blood (2009) 114 (22): 2743.

https://doi.org/10.1182/blood.V114.22.2743.2743

Published: 2009

Journal Articles

The JNK Pathway Is a Significant Determinant of Sensitivity to DNA Damaging Agents in Pre-B ALL.

Philip O. Saunders, MB, MRCP, FRACP, FRCPA, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, Linda J. Bendall, BSc, PhD

Blood (2009) 114 (22): 3786.

https://doi.org/10.1182/blood.V114.22.3786.3786

Published: 2009

Journal Articles

CCR5 Expression On Circulating Blood DC Post-Allogeneic Hemopoietic Cell Transplant Is Highly Predictive for the Development of Clinically Significant Acute Graft Versus Host Disease.

Mary M Sartor, BSc, MSc, Jenny Lau, BSc, hons, David J Gottlieb, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA

Blood (2009) 114 (22): 2251.

https://doi.org/10.1182/blood.V114.22.2251.2251

Published: 2009

Journal Articles

Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia

Roman Crazzolara, Adam Cisterne, Marilyn Thien, John Hewson, Rana Baraz, Kenneth F. Bradstock, Linda J. Bendall

Blood (2009) 113 (14): 3297–3306.

https://doi.org/10.1182/blood-2008-02-137752

Published: 2009

Includes: Supplemental data

Journal Articles

Dose Escalated RAD001 (Everolimus) Enhances Chemosensitivity in Precursor-B Acute Lymphoblastic Leukemia, through a JNK Dependent Suppression of Cell Cycle Checkpoint Regulation.

Philip O. Saunders, MB, MRCP, FRACP, FRCPA, Kenneth F. Bradstock, MB, PhD, FRACP, FRCPA, Linda J. Bendall, BSc, PhD

Blood (2008) 112 (11): 1604.

https://doi.org/10.1182/blood.V112.11.1604.1604

Published: 2008

Journal Articles

A Phase 1 and Correlative Biological Study of CSL360 (anti-CD123 mAb) in AML

Andrew W. Roberts, MBBS, PhD, Simon He, MBBS, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, Mark S Hertzberg, MBBS, FRACP, FRCP, PhD, Simon T S Durrant, MRCS, MBBS, MRCP, FRCP, David Ritchie, MBChB, FRACP, FRCPA, PhD, Ian D. Lewis, MBBS, PhD, FRACP, FRCPA, Paula Marlton, MBBS, FRACP, FRCPA, Andrew J McLachlan, PhD, Trina M Yeadon, PhD, Samantha J Busfield, PhD, Megan J Barnden, PhD, Roslyn Davis, BSc(Hons), Sarah Hosback, PhD, Danijela Mirosa, PhD, Mark Biondo, PhD, Simone Bamford, MBBS, FRACGP, Mark DeWitte, VMD, Russell Basser, MBBS, MD, FRACP

Blood (2008) 112 (11): 2956.

https://doi.org/10.1182/blood.V112.11.2956.2956

Published: 2008

Journal Articles

Best Approach for Harvesting Bone Marrow to Maximize TNC and CD34+ Cell Counts

Nalini K Pati, MBBS, MD, DNB, Frances Garvin, BSc, Vicki Antonenas, BSc, Ian Kerridge, FRACP, FRCPA, PhD, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, David J Gottlieb, MD, FRACP, FRCPA

Blood (2008) 112 (11): 3468.

https://doi.org/10.1182/blood.V112.11.3468.3468

Published: 2008

NARROW

High Risk Genomic Alterations Identified at the Time of Diagnosis Are Strongly Associated with MRD and Subsequent Poor Outcomes in AYA ALL Patients Treated on a Pediatric Inspired Chemotherapy Regimen

High-Annealing-Temperature PCR (HAT-PCR) Enables Sensitive Quantification of Minimal Residual Disease (MRD) in Blood in Acute Lymphoblastic Leukaemia (ALL)

Improved Concordance of Minimal Residual Disease Measurements By Quantitative PCR and 10-Color Flow Cytometry in Pediatric Acute Lymphoblastic Leukemia

Alterations in the Cell Cycle of Acute Lymphoblastic Leukemia Cells Resistant to Everolimus

Final Analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) APML4 Trial: All- Trans Retinoic Acid (ATRA), Intravenous Arsenic Trioxide (ATO) and Idarubicin (IDA) As Initial Therapy for Acute Promyelocytic Leukemia (APL)

Evaluation Of Sphingosine Kinase 1 As a Therapeutic Target In B-Lineage Acute Lymphoblastic Leukemia

Thalidomide Consolidation Post Autologous Stem Cell Transplant (ASCT) For Multiple Myeloma (MM) Is Cost-Effective With Durable Survival Benefit At 5 Years Post Randomisation: Final Analysis Of The ALLG MM6 Study

Identification of Sphingosine Kinases As Therapeutic Targets in B-Lineage Acute Lymphoblastic Leukemia

Effects of G-CSF On Acute Lymphoblastic Leukemia.

Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice

Upregulation of the Chemokine Receptor CCR5 on CD16+ Myeloid Blood Dendritic Cells in Allogeneic Hemopoietic Cell Transplant Patients Predicts for Acute Graft Versus Host Disease

Increased Production of the Inflammatory Cytokine IL12p70 by Activated Human Blood Dendritic Cells Is Associated with Increased Severity of Acute Graft Vs Host Disease Post Allogeneic Hemopoietic Cell Transplantation

Factors Predicting the Outcome of the Blood and Marrow Transplant Patients Admitted to Intensive Care Unit.

Combining RAD001 (Everolimus) with Proteasome Inhibitors Bortezomib (Velcade) or MG132 Significantly Enhances Pre-B ALL Cell Death in Vitro.

The JNK Pathway Is a Significant Determinant of Sensitivity to DNA Damaging Agents in Pre-B ALL.

CCR5 Expression On Circulating Blood DC Post-Allogeneic Hemopoietic Cell Transplant Is Highly Predictive for the Development of Clinically Significant Acute Graft Versus Host Disease.

Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia

Dose Escalated RAD001 (Everolimus) Enhances Chemosensitivity in Precursor-B Acute Lymphoblastic Leukemia, through a JNK Dependent Suppression of Cell Cycle Checkpoint Regulation.

A Phase 1 and Correlative Biological Study of CSL360 (anti-CD123 mAb) in AML

Best Approach for Harvesting Bone Marrow to Maximize TNC and CD34+ Cell Counts

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American Society of Hematology

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