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Leif Bergsagel, M.D.
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Journal Articles

Intracellular Accumulation Of Light Chains Caused By Lenalidomide, and Mediated Via CRBN, Causes Major ER Stress and Is Implicated In The Synergistic Combination Of Imids and Proteasome Inhibitors

Sinto Sebastian, Ph.D., Yuan Xiao Zhu, PhD, Esteban Braggio, Ph.D., Sonali Panchabhai, MBBS, Chang-Xin Shi, Ph.D., Gregory Ahmann, BS, Leif Bergsagel, M.D., Rafael Fonseca, M.D.
Journal: Blood
Blood (2013) 122 (21): 4434.
https://doi.org/10.1182/blood.V122.21.4434.4434
Published: 2013
Journal Articles

Repair Of DNA Double Strand Breaks By Insertion Of Nucleotide Sequences Derived From Distant Regions Of The Genome

Masahiro Onozawa, MD, PhD., Zhenhua Zhang, Yoo Jung Kim, Liat Goldberg, PhD, Tamas Varga, PhD, Leif Bergsagel, M.D., Michael Kuehl, MD, Peter D Aplan, MD
Journal: Blood
Blood (2013) 122 (21): 1243.
https://doi.org/10.1182/blood.V122.21.1243.1243
Published: 2013
Journal Articles

The Comprehensive Genomic Characterization Of All Commercially and Non-Commercially Available Multiple Myeloma Cell Lines

Venkata D Yellapantula, Kristi Allen, BS, Diane F. Jelinek, PhD, Leif Bergsagel, M.D., Jonathan J. Keats, PhD
Journal: Blood
Blood (2013) 122 (21): 1914.
https://doi.org/10.1182/blood.V122.21.1914.1914
Published: 2013
Journal Articles

Results From the Phase II Dose Expansion of Cyclophosphamide, Carfilzomib, Thalidomide and Dexamethasone (CYCLONE) in Patients with Newly Diagnosed Multiple Myeloma

Joseph R. Mikhael, MD, Craig B. Reeder, MD, Edward N. Libby, III, MD, Luciano J. Costa, MD, PhD, P. Leif Bergsagel, M.D., Francis Buadi, MD, Angela Mayo, PA, Katherine Gano, Cassandra Wolf, Amylou Constance Dueck, PhD, A. Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 445.
https://doi.org/10.1182/blood.V120.21.445.445
Published: 2012
Journal Articles

Cereblon Binding IMiD Small Molecules Mediate Myeloma Cell Death Via IRF4

Yuan Xiao Zhu, Ph.D., Chang-Xin Shi, Ph.D., Laura Bruins, Klaus Martin Kortuem, MD, Jessica Schmidt, Xiu-Bao Chang, Ph.D., Esteban Braggio, Ph.D., Leif Bergsagel, M.D., Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 1807.
https://doi.org/10.1182/blood.V120.21.1807.1807
Published: 2012
Journal Articles

BP-2-047, a Novel Small-Molecule Inhibitor of Stat3 Is Active in Myeloma Pre-Clinical Models: Rationale for Treatment of Stat3-Dependent Multiple Myeloma

Victor Hugo Jimenez-Zepeda, MD, Brent DG Page, BS, Li Zhia Hua, Ellen Wei, Leif Bergsagel, M.D., Patrick T Gunning, PhD, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2012) 120 (21): 576.
https://doi.org/10.1182/blood.V120.21.576.576
Published: 2012
Journal Articles

A Phase II Trial of Myeloma Induction Therapy with Cyclophosphamide, Bortezomib, and Dexamethasone (Cybor-D): Improved Response over Historical Lenalidomide-Dexamethasone Controls.

Craig B. Reeder, MD, Donna E. Reece, M.D., Rafael Fonseca, M.D., P. Leif Bergsagel, M.D., Joseph Hentz, MSc., Nicholas A. Pirooz, BSc., Jacy E. Boesiger, RN., Jesus G. Pisa, M.D., Vishal Kukreti, M.D., Christine Chen, M.D., Suzanne Trudel, M.D., Joseph R. Mikhael, M.D., Martha Lacy, M.D., S. Vincent Rajkumar, M.D., A. Keith Stewart, M.D.
Journal: Blood
Blood (2007) 110 (11): 3601.
https://doi.org/10.1182/blood.V110.11.3601.3601
Published: 2007
Journal Articles

Plasma Cell Folate Receptor Overexpression Differentiates Multiple Myeloma from Monoclonal Gammopathy of Undetermined Significance and Smoldering Myeloma.

Patricia Greipp, D.O., Greg Cascino, Teresa Kimlinger, Vincent Rajkumar, M.D., Franklyn G. Prendergast, Ph.D., M.D., Rafael Fonseca, M.D., P. Leif Bergsagel, M.D., Philip S. Low, Ph.D., Philip R. Greipp, M.D.
Journal: Blood
Blood (2004) 104 (11): 3649.
https://doi.org/10.1182/blood.V104.11.3649.3649
Published: 2004
Journal Articles

Sequencing the Multiple Myeloma Kinome: Absence of Mutation in Known Malignancy-Associated Kinases.

Jaime O. Claudio, Ph.D., Razi Khaja, B.Sc., Lihua Zhuang, M.D., Meenakshi Bali, B.Sc., Kamalanayani Sivananthan, B.Sc., Constantine C. Christopoulos, B.Sc., Rafael Fonseca, M.D., P. Leif Bergsagel, M.D., Stephen W. Scherer, Ph.D., A. Keith Stewart, M.D.
Journal: Blood
Blood (2004) 104 (11): 783.
https://doi.org/10.1182/blood.V104.11.783.783
Published: 2004