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Journal Articles

Accelerating Drug Discovery: AI-Powered Indication Exploration for Ropeginterferon Alfa-2b

Free
Erik R Sampson, Yi-Chien Chang, Kuan-Chun Huang, Tom Lin, Prasanna Baskar, Mei-Ling Yang, Ali Sepahi, Dobeen Hwang, Jack Huck, Ming-Tang Chen, Emily Huang, Ivana Grbesa, Francesco Lamanna, Andreas Kramer, Andrew Srisuwananukorn, Lih-Ling Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4982.
https://doi.org/10.1182/blood-2024-210640
Published: 2024
Journal Articles

Impact of BEAM-101 Treatment on Red Blood Cell Hemoglobin Expression, Rheology and Sickling Properties: Initial Data from the BEACON Phase 1/2 Study of Autologous CD34 + Base Edited Hematopoietic Stem Cells in Sickle Cell Disease

Free
Priya S. Chockalingam, Ling Lin, Guo Chen, Alex C. Minella, Yinzhong Chen, Vivien Sheehan, Nan Zhang, Myriam Armant, Aliya U. Zaidi, Robert Goodrich, Patrick C. Hines, Sunita Goyal, Amy Simon
Journal: Blood
Blood (2024) 144 (Supplement 1): 4957.
https://doi.org/10.1182/blood-2024-200875
Published: 2024
Journal Articles

Initial Results from the BEACON Clinical Study: A Phase 1/2 Study Evaluating the Safety and Efficacy of a Single Dose of Autologous CD34+ Base Edited Hematopoietic Stem Cells (BEAM-101) in Patients with Sickle Cell Disease with Severe Vaso-Occlusive Crises

Free
Ashish O. Gupta, Akshay Sharma, Haydar Frangoul, Jignesh Dalal, Julie Kanter, Asif Alavi, John DiPersio, Mary Eapen, Jennifer J. Jaroscak, Ernesto Ayala, Edward D. Ziga, Stacey Rifkin-Zenenberg, Alex C. Minella, Guo Chen, Yinzhong Chen, Priya S. Chockalingam, Ling Lin, Marcelyne Joseney-Antoine, Leanne Ianniello, Beth Gardner, Adam J. Hartigan, Giuseppe Ciaramella, Sunita Goyal, Amy Simon, Alexis Thompson, Matthew M. Heeney
Journal: Blood
Blood (2024) 144 (Supplement 1): 513.
https://doi.org/10.1182/blood-2024-204888
Published: 2024
Journal Articles

Complementary Base Editing Approaches for the Treatment of Sickle Cell Disease and Beta Thalassemia

Free
Ling Lin, PhD, Adrian P. Rybak, PhD, Conrad Rinaldi, M.S., Jonathan Yen, PhD, Yanfang Fu, PhD, Elsie Akrawi, Sarah Smith, Scott J. Haskett, M.S., Minerva E. Sanchez, Yeh-Chuin Poh, PhD, Michael S. Packer, PhD, Nicole M. Gaudelli, PhD, Manmohan Singh, PhD, Giuseppe Ciaramella, PhD, B.Sc., Dana N. Levasseur, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3352.
https://doi.org/10.1182/blood-2019-126710
Published: 2019
Journal Articles

Treatment Patterns and Survival Outcomes in Latin American Patients with Newly Diagnosed Multiple Myeloma: A Retrospective Medical Chart Review Study, 2008-2016

Free
Vania T M Hungria, MD PhD, Deborah M. Martinez-Banos, Christian Ramos Penafiel, Carlos Eduardo Miguel, Jorge Vela-Ojeda, MD PhD, Guillermina Remaggi, Fernando Barroso Duarte, Carmen Cao, Maria Silvana Cugliari, Telma Santos, Eduardo Santos, Gerardo Machnicki, Jennifer Hsiang-Ling Lin, Yen-Wen Chen, Paula Barreyro
Journal: Blood
Blood (2017) 130 (Supplement 1): 2113.
https://doi.org/10.1182/blood.V130.Suppl_1.2113.2113
Published: 2017
Journal Articles

EPCR Guides Hematopoietic Stem Cells Homing to the Bone Marrow Independently of Niche Clearance

Free
Shiri Gur-Cohen, PhD, Francesca Avemaria, PhD, Orit Kollet, PhD, Seymen Avci, MSc, Tomer Itkin, PhD, Saravana K. Ramasamy, PhD, Anjali P. Kusumbe, PhD, Karin Golan, PhD, Eman Khatib-Massalha, Msc, Anju Kumari, PhD, Mayela M. Carolina, PhD, Wei-Ling Lin, PhD, Qing-Cissy Yu, PhD, Hua-Lin Wu, PhD, Yi Arial Zeng, PhD, Ralf H. Adams, PhD, Conway M. Edward, PhD, Elizabeth J. Shpall, MD, Ayelet Erez, PhD, Irit Sagi, PhD, Charles T. Esmon, PhD, Wolfram Ruf, MD, Tsvee Lapidot, PhD
Journal: Blood
Blood (2016) 128 (22): 4538.
https://doi.org/10.1182/blood.V128.22.4538.4538
Published: 2016
Journal Articles

CLEC5A is critical for dengue virus–induced inflammasome activation in human macrophages

Free
Ming-Fang Wu, Szu-Ting Chen, An-Hang Yang, Wan-Wan Lin, Yi-Ling Lin, Nien-Jung Chen, I-Shuen Tsai, Lei Li, Shie-Liang Hsieh
Journal: Blood
Blood (2013) 121 (1): 95–106.
https://doi.org/10.1182/blood-2012-05-430090
Published: 2013
Includes: Supplemental data
Journal Articles

Complete Sequencing and Comparison of 12 Normal Karyotype M1 AML Genomes with 12 t(15;17) Positive M3-APL Genomes

Free
John S. Welch, MD, PhD, David Larson, PhD, Li Ding, PhD, Michael D. McLellan, Tamara Lamprecht, BS, Cyriac Kandoth, PhD, Jacqueline E. Payton, MD, PhD, Jack Baty, BA, Christopher C. Harris, BS, Cheryl F. Lichti, PhD, Robert S. Fulton, MS, David J. Dooling, PhD, Daniel C Koboldt, MS, Heather Schmidt, BS, Qunyuan Zhang, PhD, John R. Osborne, BS, Ling Lin, MS, Michelle O'Laughlin, BS, Joshua F. McMichael, BS, Kim D. Delehaunty, BA, Sean D. McGrath, MS, Lucinda A. Fulton, MS, Vincent J Magrini, PhD, Tammi L. Vickery, BS, Todd Wylie, Jason Walker, BA, BS, Peter Westervelt, MD, PhD, Michael H. Tomasson, MD, Mark A. Watson, MD, PhD, Sharon Heath, William D. Shannon, PhD, Rakesh Nagarajan, MD, PhD, Daniel C. Link, MD, Timothy Graubert, MD, John F. DiPersio, MD, PhD, Elaine R. Mardis, PhD, Richard K. Wilson, PhD, Timothy J Ley, MD
Journal: Blood
Blood (2011) 118 (21): 404.
https://doi.org/10.1182/blood.V118.21.404.404
Published: 2011
Journal Articles

Mutations In the DNA Methyltransferase Gene DNMT3A Are Highly Recurrent In Patients with Intermediate Risk Acute Myeloid Leukemia, and Predict Poor Outcomes

Free
Timothy J Ley, MD, Li Ding, PhD, Matthew J. Walter, MD, Michael D. McLellan, BS, Tamara Lamprecht, BS, David E. Larson, PhD, Cyriac Kandoth, PhD, Jacqueline E. Payton, MD, PhD, Jack Baty, BA, John S. Welch, MD, PhD, Christopher C. Harris, BS, Cheryl F. Lichti, PhD, R. Reid Townsend, MD, Robert S. Fulton, MS, David J. Dooling, PhD, Daniel C. Koboldt, MS, Heather Schmidt, BS, Qunyuan Zhang, PhD, John R. Osborne, BS, Ling Lin, MS, Michelle O'Laughlin, BS, Joshua F. McMichael, BS, Kim D. Delehaunty, BA, Sean D. McGrath, MS, Lucinda A. Fulton, MS, Vincent J. Magrini, PhD, Tammi L. Vickery, BS, Jasreet Hundal, MS, Lisa L. Cook, Joshua J. Conyers, Gary W. Swift, BS, Jerry P. Reed, MS, Patricia A. Alldredge, MS, Todd Wylie, BS, Jason Walker, BA, BS, Joelle Kalicki-Veizer, BS, Mark A. Watson, MD, PhD, Sharon Heath, William D. Shannon, PhD, Nobish Varghese, MS, Rakesh Nagarajan, MD, PhD, Peter Westervelt, MD, PhD, Michael H. Tomasson, MD, Daniel C. Link, MD, Timothy A. Graubert, MD, John F. DiPersio, MD, PhD, Elaine R. Mardis, PhD, Richard K. Wilson, PhD
Journal: Blood
Blood (2010) 116 (21): 99.
https://doi.org/10.1182/blood.V116.21.99.99
Published: 2010
Journal Articles

Variable correction of host defense following gene transfer and bone marrow transplantation in murine X-linked chronic granulomatous disease

Free
Mary C. Dinauer, Mary A. Gifford, Nancy Pech, Ling Lin Li, Patricia Emshwiller
Journal: Blood
Blood (2001) 97 (12): 3738–3745.
https://doi.org/10.1182/blood.V97.12.3738
Published: 2001
Journal Articles

Long-Term Correction of Phagocyte NADPH Oxidase Activity by Retroviral-Mediated Gene Transfer in Murine X-Linked Chronic Granulomatous Disease

Free
Mary C. Dinauer, Ling Lin Li, Helga Björgvinsdóttir, Chunjin Ding, Nancy Pech
Journal: Blood
Blood (1999) 94 (3): 914–922.
https://doi.org/10.1182/blood.V94.3.914.415a11_914_922
Published: 1999
Journal Articles

Retroviral-Mediated Gene Transfer of gp91 phox Into Bone Marrow Cells Rescues Defect in Host Defense Against Aspergillus fumigatus in Murine X-Linked Chronic Granulomatous Disease

Free
Helga Björgvinsdóttir, Chunjin Ding, Nancy Pech, Mary A. Gifford, Ling Lin Li, Mary C. Dinauer
Journal: Blood
Blood (1997) 89 (1): 41–48.
https://doi.org/10.1182/blood.V89.1.41
Published: 1997