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Luciana L. Almada
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Journal Articles

Clinical Categorization of Chronic Myelomonocytic Leukemia into Proliferative and Dysplastic Subtypes Correlates with Distinct Genomic, Transcriptomic and Epigenomic Signatures

Ryan M. Carr, MD PhD, Terra Lasho, PhD, David Marks, PhD, Ezequiel Tolosa, PhD, Luciana L Almada, PhD, Bonnie Alver, PhD, Moritz Binder, MDMPH, Stephanie Safgren, PhD, Isaac Horn, Kurt Berger, Abhishek A Mangaonkar, MBBS, Guadalupe Belen Antelo, MD, Giacomo Coltro, MD, Christopher Pin, PhD, Thomas E. Witzig, MD, Keith Robertson, PhD, Matthew T Howard, MD, Klaus Geissler, MD, Naseema Gangat, MBBS, Ayalew Tefferi, MD, Animesh Pardanani, MBBS, PhD, Aref Al-Kali, MD, Mark Litzow, MD, Michelle A Elliott, MD, Scott H. Kaufmann, MD PhD, Martin Fernandez-Zapico, MD, Martin Fernandez-Zapico, MD, Mrinal M Patnaik, MDMBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 1710.
https://doi.org/10.1182/blood-2019-123877
Published: 2019
Journal Articles

MLL1 Modulates IgM and Inflammatory Cytokines in Waldenstrom's Macroglobulinemia

Mona Karbalivand, MSc, BSc, Weiguo Han, PhD, Luciana L Almada, PhD, Stephen M Ansell, MD PhD, Martin Fernandez-Zapico, MD, Sherine F Elsawa, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3966.
https://doi.org/10.1182/blood-2019-125833
Published: 2019
Journal Articles

Bromodomain and Extra Terminal Domain (BET) Inhibitors Sensitize Chronic Myelomonocytic Leukemia (CMML) to PIM Inhibition Via Downregulation of Mir-33a

Christopher Letson, BS, Alexis Vedder, BS, Ariel Quintana, PhD, Phillip Liu, PhD, Brett Reid, Maria E Balasis, Hannah Newman, BS, Traci Kruer, PhD, Luciana L Almada, PhD, Guolin Zhang, PhD, Martin Fernandez-Zapico, MD, Mrinal M Patnaik, MDMBBS, Jeffrey E. Lancet, MD, Rami S. Komrokji, MD, P.K. Epling-Burnette, PharmD, PhD, Alan F. List, MD, Eric B. Haura, MD, Gary W. Reuther, Thomas A. Sellers, PhD, Holly K. Koblish, PhD, Eric Padron, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4220.
https://doi.org/10.1182/blood-2019-128165
Published: 2019
Journal Articles

Peripheral Blood Cell Sorting Strategies for Transcriptomic Analysis in Chronic Myelomonocytic Leukemia

Moritz Binder, MDMPH, Ryan Carr, MD PhD, Nathalie Droin, PhD, Abhishek A Mangaonkar, MBBS, Giacomo Coltro, MD, Luciana L Almada, PhD, David Marks, PhD, Kurt Berger, Terra Lasho, PhD, Naseema Gangat, MBBS, Christopher Pin, PhD, Martin Fernandez-Zapico, MD, Eric Solary, MD PhD, Mrinal M Patnaik, MDMBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4232.
https://doi.org/10.1182/blood-2019-122187
Published: 2019
Journal Articles

Gene Expression Profiling Identifies Distinct Signatures for Dysplastic and Proliferative Chronic Myelomonocytic Leukemia

Mrinal M Patnaik, MBBS, Daniela Barraco, MD, Terra L. Lasho, PhD, Ezequiel Tolosa, PhD, Luciana L. Almada, PhD, Jaime I Davila, PhD, Christy Finke, BS, Curtis A. Hanson, MD, Rhett P. Ketterling, MD, Éric Solary, MD PhD, Nathalie M. Droin, PhD, Naseema Gangat, MBBS, Aref Al-Kali, MD, Martin E. Fernandez-Zapico, MD, Ayalew Tefferi, MD
Journal: Blood
Blood (2016) 128 (22): 110.
https://doi.org/10.1182/blood.V128.22.110.110
Published: 2016
Journal Articles

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

Seongseok Yun, Nicole D. Vincelette, Katherine L. B. Knorr, Luciana L. Almada, Paula A. Schneider, Kevin L. Peterson, Karen S. Flatten, Haiming Dai, Keith W. Pratz, Allan D. Hess, B. Douglas Smith, Judith E. Karp, Andrea E. Wahner Hendrickson, Martin E. Fernandez-Zapico, Scott H. Kaufmann
Journal: Blood
Blood (2016) 127 (22): 2711–2722.
https://doi.org/10.1182/blood-2015-02-629485
Published: 2016
Includes: Supplemental data
Journal Articles

mTOR Dual Inhibitor Induced Cytotoxicity Depends on 4EBP1/c-Myc/Puma and NFkB/Egr-1/Bim Pathways in Human Lymphoid Malignancies

Seongseok Yun, MD PhD, Nicole D. Vincelette, Katherine L. B. Knorr, PhD, Luciana L. Almada, PhD, Paula A. Schneider, Kevin L. Peterson, PhD, Karen S. Flatten, Allan D. Hess, PhD, B. Douglas Smith, MD, Judith E. Karp, MD, Martin E. Fernandez-Zapico, MD, Scott H. Kaufmann, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3705.
https://doi.org/10.1182/blood.V126.23.3705.3705
Published: 2015
Journal Articles

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma

Rebecca L. Boddicker, N. Sertac Kip, Xiaoming Xing, Yu Zeng, Zhi-Zhang Yang, Jeong-Heon Lee, Luciana L. Almada, Sherine F. Elsawa, Ryan A. Knudson, Mark E. Law, Rhett P. Ketterling, Julie M. Cunningham, Yanhong Wu, Matthew J. Maurer, Megan M. O’Byrne, James R. Cerhan, Susan L. Slager, Brian K. Link, Julie C. Porcher, Deanna M. Grote, Diane F. Jelinek, Ahmet Dogan, Stephen M. Ansell, Martin E. Fernandez-Zapico, Andrew L. Feldman
Journal: Blood
Blood (2015) 125 (20): 3118–3127.
https://doi.org/10.1182/blood-2014-05-578575
Published: 2015
Includes: Supplemental data
Journal Articles

A Novel Mechanism of GLI2 Mediated Regulation of IgM Secretion in Waldenström Macroglobulinemia

David A. Jackson, Timothy D. Smith, MS, Nansalmaa Amarsaikhan, PhD, Ann Vrabel, Ezequiel Tolosa, PhD, Luciana L. Almada, PhD, Martin E. Fernandez-Zapico, MD, Sherine F. Elsawa, PhD
Journal: Blood
Blood (2014) 124 (21): 3006.
https://doi.org/10.1182/blood.V124.21.3006.3006
Published: 2014
Journal Articles

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity

Sherine F. Elsawa, Anne J. Novak, Steven C. Ziesmer, Luciana L. Almada, Lucy S. Hodge, Deanna M. Grote, Thomas E. Witzig, Martin E. Fernandez-Zapico, Stephen M. Ansell
Journal: Blood
Blood (2011) 118 (20): 5540–5549.
https://doi.org/10.1182/blood-2011-04-351742
Published: 2011
Journal Articles

GLI2, An Effector of the Hedgehog Pathway, Is a Novel Regulator of IL6 Oncogenic Function In the Tumor Microenvironment

Sherine F. Elsawa, PhD, Luciana L. Almada, PhD, Steven Ziesmer, Thomas E. Witzig, MD, Stephen M. Ansell, MD, PhD, Martin E. Fernandez-Zapico, MD
Journal: Blood
Blood (2010) 116 (21): 613.
https://doi.org/10.1182/blood.V116.21.613.613
Published: 2010
Journal Articles

A Novel Pro-Survival Function of Cyclin-D1 Underlies Its Oncogenic Role and Potential as a Therapeutic Target In Mantle Cell Lymphoma

Elena Beltran, PhD, Vicente Fresquet, PhD, Javier Martinez-Useros, Jose A. Richter-Larrea, PhD, Ainara Sagardoy, PhD, Izaskun Sesma, Luciana L. Almada, PhD, Santiago Montes-Moreno, MD, Stefan Gesk, MD, Reiner Siebert, Prof., Dr., med., MaJose Calasanz, PhD, Felipe Prosper, MD, Miguel A. Piris, MD, Martin E. Fernandez-Zapico, MD, Jose A Martinez-Climent, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 769.
https://doi.org/10.1182/blood.V116.21.769.769
Published: 2010
Journal Articles

Comprehensive Analysis of the Waldenström Macroglobulinemia “Cytokine Milieu” Reveals a Novel Role of Rantes Signaling in the Regulation of Immunoglobulin Production

Sherine F. Elsawa, PhD, Anne J. Novak, Ph.D., Steven C Ziesmer, Luciana L Almada, Ph.D., Martin E Fernandez-Zapico, M.D., Thomas E Witzig, M.D., Stephen M. Ansell, M.D./Ph.D.
Journal: Blood
Blood (2008) 112 (11): 618.
https://doi.org/10.1182/blood.V112.11.618.618
Published: 2008