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Journal Articles

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease

Sydney X. Lu, Onder Alpdogan, Janine Lin, Robert Balderas, Roberto Campos-Gonzalez, Xiao Wang, Guo-Jian Gao, David Suh, Christopher King, Melanie Chow, Odette M. Smith, Vanessa M. Hubbard, Johanne L. Bautista, Javier Cabrera-Perez, Johannes L. Zakrzewski, Adam A. Kochman, Andrew Chow, Gregoire Altan-Bonnet, Marcel R. M. van den Brink

Blood (2008) 112 (13): 5254–5258.

https://doi.org/10.1182/blood-2008-03-147322

Published: 2008

Includes: Supplemental data

Journal Articles

Rapidly proliferating CD44 hi peripheral T cells undergo apoptosis and delay posttransplantation T-cell reconstitution after allogeneic bone marrow transplantation

S. Önder Alpdogan, Sydney X. Lu, Neel Patel, Suzanne McGoldrick, David Suh, Tulin Budak-Alpdogan, Odette M. Smith, Jeremy Grubin, Christopher King, Gabrielle L. Goldberg, Vanessa M. Hubbard, Adam A. Kochman, Marcel R. M. van den Brink

Blood (2008) 112 (12): 4755–4764.

https://doi.org/10.1182/blood-2008-02-142737

Published: 2008

Includes: Supplemental data

Journal Articles

Discovery and Validation of STAT-3 and ERK1/2 Phosphorylation as Critical for the Function of Alloactivated T Cells in Acute Graft-Versus-Host-Disease Via a Novel Technique for Drug Discovery.

Sydney X. Lu, Onder Alpdogan, Roberto Campos, Xiao Wang, Guo-Jian Gao, Melanie Chow, Janine Lin, David Suh, Christopher King, Vanessa M. Hubbard, Johanne L. Bautista, Adam A. Kochman, Johannes L. Zakrzewski, O. Marsinay Smith, Jeremy Grubin, Andrew Chow, Neel Patel, Marcel R.M. van den Brink

Blood (2007) 110 (11): 3236.

https://doi.org/10.1182/blood.V110.11.3236.3236

Published: 2007

Journal Articles

Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration

Önder Alpdogan, Vanessa M. Hubbard, Odette M. Smith, Neel Patel, Sydney Lu, Gabrielle L. Goldberg, Daniel H. Gray, Jared Feinman, Adam A. Kochman, Jeffrey M. Eng, David Suh, Stephanie J. Muriglan, Richard L. Boyd, Marcel R. M. van den Brink

Blood (2006) 107 (6): 2453–2460.

https://doi.org/10.1182/blood-2005-07-2831

Published: 2006

Includes: Supplemental data

Journal Articles

Remodeling specific immunity by use of MHC tetramers: demonstration in a graft-versus-host disease model

Barry J. Kappel, Javier Pinilla-Ibarz, Adam A. Kochman, Jeffrey M. Eng, Vanessa M. Hubbard, Ingrid Leiner, Eric G. Pamer, Glen Heller, Marcel R. M. van den Brink, David A. Scheinberg

Blood (2006) 107 (5): 2045–2051.

https://doi.org/10.1182/blood-2005-07-2828

Published: 2006

Journal Articles

Absence of β7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine

Elisha Waldman, Sydney X. Lu, Vanessa M. Hubbard, Adam A. Kochman, Jeffrey M. Eng, Theis H. Terwey, Stephanie J. Muriglan, Theo D. Kim, Glenn Heller, George F. Murphy, Chen Liu, Onder Alpdogan, Marcel R. M. van den Brink

Blood (2006) 107 (4): 1703–1711.

https://doi.org/10.1182/blood-2005-08-3445

Published: 2006

Journal Articles

Adoptive Transfer of In Vitro Generated T Cell Precursors Enhances Donor T Cell Reconstitution and Graft-Versus-Tumor Activity in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.

Johannes L. Zakrzewski, MD, Adam A. Kochman, Sidney X. Lu, Theis H. Terwey, MD, Theo D. Kim, MD, Vanessa M. Hubbard, Stephanie J. Muriglan, David Suh, Javier Cabrera-Perez, Radhika Radhakrishnan, Glenn Heller, PhD, Juan Carlos Zuniga-Pflucker, PhD, Onder Alpdogan, MD, Marcel R.M. van den Brink, MD, PhD

Blood (2005) 106 (11): 63.

https://doi.org/10.1182/blood.V106.11.63.63

Published: 2005

Journal Articles

Signaling Profiles of T Cells during Allogeneic Hematopoietic Stem Cell Transplantation.

Sydney X. Lu, BA, Vanessa M. Hubbard, BS, Melanie Y. Chow, Theo D. Kim, MD, David Y. Suh, BS, Adam Kochman, BA, Johannes Zakrzewski, MD, Javier Cabrera-Perez, Onder Alpdogan, MD, Marcel M.R.M. van den Brink, MD, PhD

Blood (2005) 106 (11): 1262.

https://doi.org/10.1182/blood.V106.11.1262.1262

Published: 2005

Journal Articles

Graft-Versus-Tumor Activity Against Renal Cell Carcinoma in a Mouse Model of HSCT.

Teresa Ramirez-Montagut, MD, PhD, Andrew Chow, BA (2006), Adam A. Kochman, BS, Vanessa M. Hubbard, BS, David Suh, BA, Odette M. Smith, BA, Hamad Sindhi, BA (2006), Theis H. Terwey, MD, Theo D. Kim, MD, Elisha Waldman, MD, Onder Alpdogan, MD, Marcel R.M. van den Brink, MD, PhD

Blood (2005) 106 (11): 1317.

https://doi.org/10.1182/blood.V106.11.1317.1317

Published: 2005

Journal Articles

Remodeling Specific Immunity by Use of MHC-Tetramers Distinguishes Graft-Versus-Tumor Activity from Graft-Versus-Host-Disease.

Barry J. Kappel, BA, Javier Pinilla-Ibarz, MD, Adam A. Kochman, BS, Jeffrey M. Eng, BS, Vanessa M. Hubbard, BS, Ingrid M. Leiner, MS, Eric G. Pamer, MD, Marcel R.M. van den Brink, MD, PhD, David A. Scheinberg, MD, PhD

Blood (2005) 106 (11): 1300.

https://doi.org/10.1182/blood.V106.11.1300.1300

Published: 2005

Journal Articles

Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation

Vanessa M. Hubbard, Jeffrey M. Eng, Teresa Ramirez-Montagut, Kartono H. Tjoe, Stephanie J. Muriglan, Adam A. Kochman, Theis H. Terwey, Lucy M. Willis, Rafaella Schiro, Glen Heller, George F. Murphy, Chen Liu, Onder Alpdogan, Marcel R. M. van den Brink

Blood (2005) 106 (9): 3285–3292.

https://doi.org/10.1182/blood-2005-01-0410

Published: 2005

Journal Articles

CCR2 is required for CD8-induced graft-versus-host disease

Theis H. Terwey, Theo D. Kim, Adam A. Kochman, Vanessa M. Hubbard, Sydney Lu, Johannes L. Zakrzewski, Teresa Ramirez-Montagut, Jeffrey M. Eng, Stephanie J. Muriglan, Glenn Heller, George F. Murphy, Chen Liu, Tulin Budak-Alpdogan, Onder Alpdogan, Marcel R. M. van den Brink

Blood (2005) 106 (9): 3322–3330.

https://doi.org/10.1182/blood-2005-05-1860

Published: 2005

Journal Articles

Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation

Onder Alpdogan, Jeffrey M. Eng, Stephanie J. Muriglan, Lucy M. Willis, Vanessa M. Hubbard, Kartono H. Tjoe, Theis H. Terwey, Adam Kochman, Marcel R. M. van den Brink

Blood (2005) 105 (2): 865–873.

https://doi.org/10.1182/blood-2003-09-3344

Published: 2005

Journal Articles

Absence of Inducible Costimulator (ICOS) on Alloreactive T Cells Reduces Graft-versus-Host-Disease While Leaving Graft-Versus-Tumor Activity Intact.

Vanessa M. Hubbard, BS, Jeffrey M. Eng, BA, Kartono H. Tjoe, BA, Teresa Ramirez-Montagut, MD PhD, Stephanie J. Muriglan, MS, Adam A. Kochman, BS, Theis H. Terwey, MD, Raffaella Schiro, MD, Onder Alpdogan, MD, Marcel R.M. van den Brink, MD PhD.

Blood (2004) 104 (11): 592.

https://doi.org/10.1182/blood.V104.11.592.592

Published: 2004

Journal Articles

DNA Immunization Against Melanoma Antigens Enhances Tumor Immunity in Mice Following Sub-Lethal Irradiation and Immune Reconstitution.

Adi Diab, MD, Vanessa M. Hubbard, Adam Cohen, MD, Deonka Huggins, Adam Kochman, Jose A. Guevarra, MD, Manuel Engelhorn, PhD, Jedd D. Wolchok, MD, PhD, Marcel van den Brink, MD, PhD, Alan N. Houghton, MD, Miguel-Angel Perales, MD

Blood (2004) 104 (11): 3057.

https://doi.org/10.1182/blood.V104.11.3057.3057

Published: 2004

Journal Articles

DNA Immunization Against Melanoma Antigens Enhances Tumor Immunity in Mouse Models of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT).

Adi Diab, MD, Miguel-Angel Perales, MD, Adam Cohen, MD, Vanessa M. Hubbard, Jeff Eng, Deonka Huggins, Manuel Engelhorn, PhD, Jose A. Guevarra, MD, Onder Alpdogan, MD, Jedd D. Wolchok, MD, PhD, Adam Kochman, Alan N. Houghton, MD, Marcel van den Brink, MD, PhD

Blood (2004) 104 (11): 304.

https://doi.org/10.1182/blood.V104.11.304.304

Published: 2004

Journal Articles

Lymphocyte Function and Molecular Mechanisms of Enhanced Immune Reconstitution Following Sex Steroid Ablation and Hemopoietic Stem Cell Transplantation (HSCT).

Gabrielle L. Goldberg, BSc, Önder Alpdogan, MD, Stephanie J. Muriglan, MS, Maree Hammett, MSc, Morag K. Milton, BSc, Jeffrey M. Eng, BS, Vanessa M. Hubbard, BS, Adam Kochman, BS, Lucy M. Willis, BS, Andrew S. Greenberg, BS, Kartono H. Tjoe, MS, Jayne S. Sutherland, PhD, Ann Chidgey, PhD, Richard L. Boyd, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2004) 104 (11): 4990.

https://doi.org/10.1182/blood.V104.11.4990.4990

Published: 2004

Journal Articles

Keratinocyte Growth Factor (KGF) Is Required for Post-Natal Thymic Regeneration.

Onder Alpdogan, MD, Vanessa M. Hubbard, BS, Stephanie J. Muriglan, MS, Adam A. Kochman, BS, Jeffrey M. Eng, BA, Johannes L. Zakrzewski, MD, Gabrielle L. Goldberg, BS, Odette M. Smith, BA, Elisha Waldman, MD, Marcel R.M. van den Brink, MD, PhD

Blood (2004) 104 (11): 1231.

https://doi.org/10.1182/blood.V104.11.1231.1231

Published: 2004

Journal Articles

Surface membrane characteristics and cytochemistry of the abnormal cells in adult acute leukemia

DS Gordon, M Hubbard

Blood (1978) 51 (4): 681–692.

https://doi.org/10.1182/blood.V51.4.681.681

Published: 1978

NARROW

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease

Rapidly proliferating CD44 hi peripheral T cells undergo apoptosis and delay posttransplantation T-cell reconstitution after allogeneic bone marrow transplantation

Discovery and Validation of STAT-3 and ERK1/2 Phosphorylation as Critical for the Function of Alloactivated T Cells in Acute Graft-Versus-Host-Disease Via a Novel Technique for Drug Discovery.

Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration

Remodeling specific immunity by use of MHC tetramers: demonstration in a graft-versus-host disease model

Absence of β7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine

Adoptive Transfer of In Vitro Generated T Cell Precursors Enhances Donor T Cell Reconstitution and Graft-Versus-Tumor Activity in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.

Signaling Profiles of T Cells during Allogeneic Hematopoietic Stem Cell Transplantation.

Graft-Versus-Tumor Activity Against Renal Cell Carcinoma in a Mouse Model of HSCT.

Remodeling Specific Immunity by Use of MHC-Tetramers Distinguishes Graft-Versus-Tumor Activity from Graft-Versus-Host-Disease.

Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation

CCR2 is required for CD8-induced graft-versus-host disease

Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation

Absence of Inducible Costimulator (ICOS) on Alloreactive T Cells Reduces Graft-versus-Host-Disease While Leaving Graft-Versus-Tumor Activity Intact.

DNA Immunization Against Melanoma Antigens Enhances Tumor Immunity in Mice Following Sub-Lethal Irradiation and Immune Reconstitution.

DNA Immunization Against Melanoma Antigens Enhances Tumor Immunity in Mouse Models of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT).

Lymphocyte Function and Molecular Mechanisms of Enhanced Immune Reconstitution Following Sex Steroid Ablation and Hemopoietic Stem Cell Transplantation (HSCT).

Keratinocyte Growth Factor (KGF) Is Required for Post-Natal Thymic Regeneration.

Surface membrane characteristics and cytochemistry of the abnormal cells in adult acute leukemia

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American Society of Hematology

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American Society of Hematology

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