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Journal Articles

Raman Spectroscopy Imaging in Evaluation of Immune Cells Activation Status

Paulina Laskowska, Aleksandra Borek-Dorosz, Anna Maria Nowakowska, Aleksandra Zolyniak, Ewa Kurtz, Maciej Szydlowski, Przemysław Juszczyński, Malgorzata Baranska, Katarzyna Majzner, Piotr Mrówka

Blood (2023) 142 (Supplement 1): 7157.

https://doi.org/10.1182/blood-2023-190418

Published: 2023

Journal Articles

Label-Free Identification of Biochemical Footprints of Key Mutations in Acute Myeloid Leukemia Using Raman Spectroscopy

Paulina Laskowska, Sylwia Orzechowska, Aleksandra Borek-Dorosz, Anna Maria Nowakowska, Wiktoria Korona, Adriana Adamczyk, Patrycja Leszczenko, Aleksandra Szlachetka, Małgorzata Zasowska, Maciej Szydlowski, Przemysław Juszczyński, Malgorzata Baranska, Katarzyna Majzner, Piotr Mrówka

Blood (2023) 142 (Supplement 1): 6022.

https://doi.org/10.1182/blood-2023-190220

Published: 2023

Journal Articles

Epigenetic and Transcriptional Consequences of PIM Kinase Activity and Inhibition in Diffuse Large B-Cell Lymphoma (DLBCL)

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Zolyniak, Michal Pawlak, Ewa Jablonska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Małgorzata Bajor, Nazli Serin, Bjoern Chapuy, Przemysław Juszczyński

Blood (2023) 142 (Supplement 1): 5713.

https://doi.org/10.1182/blood-2023-189958

Published: 2023

Journal Articles

Raman Spectroscopy Imaging As a Tool to Classify Diffused Large B-Cell Lymphoma Subtypes

Patrycja Dawiec, Paulina Laskowska, Patrycja Leszczenko, Anna Maria Nowakowska, Maciej Szydlowski, Przemysław Juszczyński, Malgorzata Baranska, Katarzyna Majzner, Piotr Mrówka

Blood (2023) 142 (Supplement 1): 5040.

https://doi.org/10.1182/blood-2023-189952

Published: 2023

Journal Articles

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

Blood (2022) 140 (Supplement 1): 4189–4190.

https://doi.org/10.1182/blood-2022-168770

Published: 2022

Journal Articles

PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Matrejek, Michał Pawlak, Ewa Jabłońska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Daniela Bellarosa, Nazli Serin, Malgorzata Bajor, Bjoern Chapuy, Przemyslaw Juszczynski

Blood (2022) 140 (Supplement 1): 3044–3045.

https://doi.org/10.1182/blood-2022-167734

Published: 2022

Journal Articles

MEN1703-Mediated PIM Kinases Inhibition Impairs Protumoral and Immunosuppressive Phenotype and Functions of Macrophages in Classical Hodgkin Lymphoma

Maciej Szydlowski, Filip Garbicz, Ewa Kurtz, Justyna Żurańska, Michał Seweryn, Michał Pawlak, Patryk Górniak, Kamil Sokół, Anna Szumera-Ciećkiewicz, Monika Kawecka, Daria Owczarek, Beata Puton, Monika Prochorec-Sobieszek, Daniela Bellarosa, Michał Kurlapski, Jan Zaucha, Paweł Wołkow, Przemyslaw Juszczynski

Blood (2022) 140 (Supplement 1): 6441–6442.

https://doi.org/10.1182/blood-2022-156894

Published: 2022

Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Blood (2020) 136 (Supplement 1): 33–34.

https://doi.org/10.1182/blood-2020-134778

Published: 2020

Journal Articles

SIRT1 and HSP90alpha Are Functionally Linked and Control Mitotic Chromosome Segregation and Cell Viability in a Subset of Dlbcls

Emilia Bialopiotrowicz, PhD, Monika Noyszewska-Kania, MSc, Ewa Jabłońska, PhD, Tomasz Sewastianik, PhD, Monika Stańczak, Msc, Anna Szumera-Ciećkiewicz, MD PhD, Katarzyna Borg, PhD, Aleksandra Bluszcz, Msc, Sonia Dębek, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Patryk Górniak, PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-139319

Published: 2020

Journal Articles

Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner

Maciej Szydlowski, PhD, Michał Pawlak, PhD, Filip Garbicz, MD, Patryk Górniak, PhD, Justyna Żurańska, PhD, Magdalena Król, PhD, Bartłomiej Taciak, Maciej Białasek, Anna Szumera-Ciećkiewicz, MD PhD, Kamil Sokół, Monika Stańczak, Msc, Daria Owczarek, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Emilia Bialopiotrowicz, PhD, Michał Kurlapski, Jan Zaucha, MDPhD, Paweł Wołkow, PhD, Przemyslaw Juszczynski, MD PhD

Blood (2020) 136 (Supplement 1): 30.

https://doi.org/10.1182/blood-2020-134886

Published: 2020

Journal Articles

PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Filip Garbicz, MD, Anna Szumera-Ciećkiewicz, MD PhD, Joanna Barankiewicz, MD, Dorota Komar, PhD, Michał Pawlak, PhD, Sonia Dębek, MSc, Aleksandra Matrejek, MSc, Thorsten Stuehmer, PhD, Aleksander Salomon-Perzynski, MD, Agata Malenda, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Andrea Massimiliano Tomirotti, PhD, Ewa Lech-Marańda, MD PhD, Monika Prochorec-Sobieszek, MD PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD

Blood (2020) 136 (Supplement 1): 16–17.

https://doi.org/10.1182/blood-2020-134979

Published: 2020

Journal Articles

Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma

Maciej Szydłowski, Monika Prochorec-Sobieszek, Anna Szumera-Ciećkiewicz, Edyta Derezińska, Grażyna Hoser, Danuta Wasilewska, Olga Szymańska-Giemza, Ewa Jabłońska, Emilia Białopiotrowicz, Tomasz Sewastianik, Anna Polak, Wojciech Czardybon, Michał Gałęzowski, Renata Windak, Jan Maciej Zaucha, Krzysztof Warzocha, Krzysztof Brzózka, Przemysław Juszczyński

Blood (2017) 130 (12): 1418–1429.

https://doi.org/10.1182/blood-2017-01-760702

Published: 2017

Includes: Supplemental data

Journal Articles

Functional Link Between Heat Shock Protein HSP90alpha and Sirtuin 1 (SIRT1) in the Pathogenesis of Diffuse Large B Cell Lymphoma

Emilia Bialopiotrowicz, PhD, Tomasz Sewastianik, PhD, Monika Noyszewska-Kania, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Patryk Gorniak, PhD, Anna Polak, PhD, Przemyslaw Kiliszek, PhD, Krzysztof Warzocha, Przemyslaw Juszczynski, MD PhD

Blood (2016) 128 (22): 4120.

https://doi.org/10.1182/blood.V128.22.4120.4120

Published: 2016

Journal Articles

Downregulation of Deptor By MiR-155 Promotes Cell Survival through Activation of PI3K/AKT and NFkB Signaling in ABC-Type Diffuse Large B-Cell Lymphomas

Ewa Jablonska, PhD, Patryk Gorniak, PhD, Weronika Prusisz, MSc, Przemyslaw Kiliszek, PhD, Maciej Szydlowski, PhD, Tomasz Sewastianik, PhD, Emilia Bialopiotrowicz, PhD, Anna Polak, PhD, Monika Prochorec-Sobieszek, MD PhD Prof, Anna Szumera-Cieckiewicz, MD PhD, Krzysztof Warzocha, Przemyslaw Juszczynski, MD PhD

Blood (2016) 128 (22): 1761.

https://doi.org/10.1182/blood.V128.22.1761.1761

Published: 2016

Journal Articles

Microenvironment-Induced Expression of PIM Kinases Supports Chronic Lymphocytic Leukemia Cells Survival and Promotes CXCR4-mTOR Pathway Dependent Migration

Blood (2016) 128 (22): 3239.

https://doi.org/10.1182/blood.V128.22.3239.3239

Published: 2016

Journal Articles

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas

Maciej Szydlowski, Przemyslaw Kiliszek, Tomasz Sewastianik, Ewa Jablonska, Emilia Bialopiotrowicz, Patryk Gorniak, Anna Polak, Sergiusz Markowicz, Eliza Nowak, Monika A. Grygorowicz, Monika Prochorec-Sobieszek, Anna Szumera-Cieckiewicz, Agata Malenda, Ewa Lech-Maranda, Krzysztof Warzocha, Przemyslaw Juszczynski

Blood (2016) 127 (6): 739–748.

https://doi.org/10.1182/blood-2015-06-654111

Published: 2016

Includes: Supplemental data

Journal Articles

HIF1-Alpha and MYC Transcription Factor Signatures in B-Cell Acute Lymphoblastic Leukemia Are Associated with Positive Minimal Residual Disease Status: Therapeutic Implications

Tomasz Sewastianik, MSc, Patryk Gorniak, PhD, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Emilia Bialopiotrowicz, PhD, Ewa Jablonska, PhD, Maciej Szydlowski, PhD, Ewa Lech-Maranda, MD PhD, Katarzyna Borg, PhD, Hanna Makuch-Lasica, MSc, Adam Zabek, MSc, Piotr Mlynarz, PhD, Tomasz Stoklosa, MD PhD, Sebastian Giebel, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 1436.

https://doi.org/10.1182/blood.V126.23.1436.1436

Published: 2015

Journal Articles

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

Anna Polak, MSc, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Dominika Nowis, MDPhD, Jakub Golab, MD PhD, Sebastian Giebel, MD PhD, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 4917.

https://doi.org/10.1182/blood.V126.23.4917.4917

Published: 2015

Journal Articles

FOXO1-p300-Txn Circuit Regulates Oxidative Stress Responses in Diffuse Large B-Cell Lymphomas Characterized By Enhanced Oxidative Phosphorylation

Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Emilia Bialopiotrowicz, PhD, Ewa Jablonska, PhD, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Tomasz S. Kaminski, MSc, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 466.

https://doi.org/10.1182/blood.V126.23.466.466

Published: 2015

Journal Articles

MiR-155 Amplifies AKT and NFkB Signaling By Targeting Multiple Regulators of BCR Signal in DLBCL

Ewa Jablonska, PhD, Patryk Gorniak, PhD, Weronika Prusisz, MSc, Przemyslaw Kiliszek, MSc, Maciej Szydlowski, PhD, Tomasz Sewastianik, MSc, Emilia Bialopiotrowicz, PhD, Anna Polak, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 2455.

https://doi.org/10.1182/blood.V126.23.2455.2455

Published: 2015

NARROW

Raman Spectroscopy Imaging in Evaluation of Immune Cells Activation Status

Label-Free Identification of Biochemical Footprints of Key Mutations in Acute Myeloid Leukemia Using Raman Spectroscopy

Epigenetic and Transcriptional Consequences of PIM Kinase Activity and Inhibition in Diffuse Large B-Cell Lymphoma (DLBCL)

Raman Spectroscopy Imaging As a Tool to Classify Diffused Large B-Cell Lymphoma Subtypes

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma

MEN1703-Mediated PIM Kinases Inhibition Impairs Protumoral and Immunosuppressive Phenotype and Functions of Macrophages in Classical Hodgkin Lymphoma

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

SIRT1 and HSP90alpha Are Functionally Linked and Control Mitotic Chromosome Segregation and Cell Viability in a Subset of Dlbcls

Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner

PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma

Functional Link Between Heat Shock Protein HSP90alpha and Sirtuin 1 (SIRT1) in the Pathogenesis of Diffuse Large B Cell Lymphoma

Downregulation of Deptor By MiR-155 Promotes Cell Survival through Activation of PI3K/AKT and NFkB Signaling in ABC-Type Diffuse Large B-Cell Lymphomas

Microenvironment-Induced Expression of PIM Kinases Supports Chronic Lymphocytic Leukemia Cells Survival and Promotes CXCR4-mTOR Pathway Dependent Migration

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas

HIF1-Alpha and MYC Transcription Factor Signatures in B-Cell Acute Lymphoblastic Leukemia Are Associated with Positive Minimal Residual Disease Status: Therapeutic Implications

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

FOXO1-p300-Txn Circuit Regulates Oxidative Stress Responses in Diffuse Large B-Cell Lymphomas Characterized By Enhanced Oxidative Phosphorylation

MiR-155 Amplifies AKT and NFkB Signaling By Targeting Multiple Regulators of BCR Signal in DLBCL

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American Society of Hematology

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American Society of Hematology

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