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Renata Windak
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Journal Articles

Inhibition of Cyclin Dependent Kinase 8(CDK8): A Novel Approach to Target the Leukemia Initiating Cells (LICs) in T-Cell Acute Lymphoblastic Leukaemia (T-ALL)

Sujan Piya, Huaxian Ma, Sujan Piya, Vivian Ruvolo, Mahesh Basyal, Aniela Golas, Renata Windak, Tomasz Rzymski, Michael Andreeff, Gautam Borthakur
Journal: Blood
Blood (2021) 138 (Supplement 1): 2250.
https://doi.org/10.1182/blood-2021-148853
Published: 2021
Journal Articles

SEL120 - a First-in-Class CDK8/19 Inhibitor As a Novel Option for the Treatment of Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome - Data from Preclinical Studies and Introduction to a Phase Ib Clinical Trial

Gautam M. Borthakur, MD, William B. Donnellan, MD, Scott R. Solomon, MD, Camille Abboud, MD, Aziz Nazha, MD, Milena Mazan, PhD, Michal Mikula, MD PhD, Eliza Majewska, PhD, Katarzyna Wiklik, PhD, Aniela Golas, PhD, Marcus Järås, PhD, Marion Chapellier, PhD, Anna Polak, PhD, Arkadiusz Bialas, PhD, Renata Windak, PhD, Jerzy Ostrowski, Prof., MD PhD, Przemyslaw Juszczynski, Prof., MD PhD, Pawel Chrom, MD PhD, Tomasz Rzymski, PhD, Krzysztof Brzózka, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2651.
https://doi.org/10.1182/blood-2019-127835
Published: 2019
Journal Articles

Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma

Maciej Szydłowski, Monika Prochorec-Sobieszek, Anna Szumera-Ciećkiewicz, Edyta Derezińska, Grażyna Hoser, Danuta Wasilewska, Olga Szymańska-Giemza, Ewa Jabłońska, Emilia Białopiotrowicz, Tomasz Sewastianik, Anna Polak, Wojciech Czardybon, Michał Gałęzowski, Renata Windak, Jan Maciej Zaucha, Krzysztof Warzocha, Krzysztof Brzózka, Przemysław Juszczyński
Journal: Blood
Blood (2017) 130 (12): 1418–1429.
https://doi.org/10.1182/blood-2017-01-760702
Published: 2017
Includes: Supplemental data
Journal Articles

Microenvironment-Induced Expression of PIM Kinases Supports Chronic Lymphocytic Leukemia Cells Survival and Promotes CXCR4-mTOR Pathway Dependent Migration

Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Bartosz Pula, MD PhD, Monika Noyszewska-Kania, MSc, Hanna Makuch-Lasica, MSc, Grazyna Nowak, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Tomasz Sewastianik, PhD, Anna Polak, PhD, Ewa Lech-Maranda, MD PhD, Bozena Katarzyna Budziszewska, MD PhD, Maja Wasylecka, MD, Katarzyna Borg, PhD, Krzysztof Warzocha, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Krzysztof Brzozka, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3239.
https://doi.org/10.1182/blood.V128.22.3239.3239
Published: 2016
Journal Articles

Expression of PIM Kinases in Reed-Sternberg Cells Fosters Immune Privilege and Tumor Cell Survival in Classical Hodgkin Lymphoma

Maciej Szydlowski, PhD, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Grazyna Hoser, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Anna Polak, MSc, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Krzysztof Brzozka, PhD, Krzysztof Warzocha, MD PhD, Jan Maciej Zaucha, MD PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 819.
https://doi.org/10.1182/blood.V126.23.819.819
Published: 2015
Journal Articles

Activity of PIM Kinases in Chronic Lymphocytic Leukemia Modulates Tumor Cell Survival and Stromal Interactions through a Pleiotropic Mechanism Involving Modulation of CXCR4 - mTOR Pathway

Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Maciej Szydlowski, PhD, Tomasz Sewastianik, MSc, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Ewa Jablonska, PhD, Bozena Katarzyna Budziszewska, MD PhD, Bartosz Pula, MD, Maja Wasylecka, MD, Katarzyna Borg, PhD, Hanna Makuch-Lasica, MSc, Grazyna Nowak, MSc, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Krzysztof Brzozka, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1549.
https://doi.org/10.1182/blood.V126.23.1549.1549
Published: 2015
Journal Articles

A Novel Pan-PIM Kinase Inhibitor, SEL24-B489, Induces Apoptosis and Inhibits Proliferation of Diffuse Large B-Cell Lymphoma Cells through Inhibition of Protein Translation and Attenuation of Myc and NFkB Activity

Ewa Jablonska, PhD, Maciej Szydlowski, PhD, Emilia Bialopiotrowicz, PhD, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Anna Polak, MSc, Krzysztof Warzocha, MD PhD, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Aniela Golas, PhD, Krzysztof Brzozka, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 706.
https://doi.org/10.1182/blood.V126.23.706.706
Published: 2015