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Journal Articles

Characterization and T-Cell Repertoire of MB-CART2019.1 (Zamtocabtagene autoleucel) - Data from the Phase I Trial in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Tatjana Holzer, Stefanie Biedermann, Inga Herfort, Birte Friedrichs, Silke Holtkamp, Linda Hanssens, Mario Assenmacher, Ulf Bethke, Dina Schneider, Stefan Miltenyi, Toon Overstijns, Christoph Schmid, Francis A. Ayuk, Christoph Scheid, Anja Jühling, Udo Holtick, Philipp Gödel, Peter Borchmann, Iris Bürger

Blood (2022) 140 (Supplement 1): 4581–4583.

https://doi.org/10.1182/blood-2022-164597

Published: 2022

Journal Articles

Trial in Progress: A Randomized Phase II Study of MB-CART2019.1 Compared to Standard of Care Therapy in Patients with Relapsed/Refractory DLBCL Ineligible for High-Dose Chemotherapy and Autologous Stem Cell Transplantation - DALY 2-EU Trial

Peter Borchmann, Peter Vandenberghe, Alvaro Urbano-Ispizua, Corinne Haioun, Francois Lemonnier, Laimonas Griskevicius, Sébastien Maury, Silke Holtkamp, Birte Friedrichs, Gregor Zadoyan, Linda Hanssens, Toon Overstijns, Mario Assenmacher, Ulf Bethke, Iris Bürger, Olaf Reer, Ulrich Jaeger, Marie José Kersten

Blood (2022) 140 (Supplement 1): 12784–12785.

https://doi.org/10.1182/blood-2022-164650

Published: 2022

Journal Articles

A Phase I Dose Finding Trial of MB-CART20.1 in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Nadine Kutsch, Philipp Gödel, Udo Holtick, Anja Lohneis, Vladan Vucinic, Florentine Pia Altefrohne, Christin Schubert, Sandra Karitzky, Linda Hanssens, Mario Assenmacher, Iris Bürger, Murat Aktas, Peter Borchmann

Blood (2022) 140 (Supplement 1): 12980–12981.

https://doi.org/10.1182/blood-2022-168730

Published: 2022

Journal Articles

A Phase I Open Label Dose Escalation Study of MB-CART19.1 in Relapsed and Refractory CD19+ B Cell Malignancies, Interim Preliminary Results in Pediatric ALL, Adult ALL Including CLL Cohorts

Andreas Mackensen, Linda Hanssens, Matthias Stelljes, Wolfgang A Bethge, Tobias Feuchtinger, Annette Künkele, Michael Aigner, Alisa Yakushina, Sandra Karitzky, Silke Holtkamp, Mario Assenmacher, Marion Jurk, Georg Rauser, Dina Schneider, Claudia Rossig

Blood (2021) 138 (Supplement 1): 3836.

https://doi.org/10.1182/blood-2021-152452

Published: 2021

Journal Articles

Defined Central Memory and Stem Memory T Cell Phenotype of CD4 and CD8 CAR T Cells for the Treatment of CD19+ Acute Lymphoblastic Leukemia in an Automated Closed System

Franziska Blaeschke, MD, Theresa Kaeuferle, PhD, Judith Feucht, MD, Dana Weber, Ramin Lotfi, MD, Andrew Kaiser, PhD, Mario Assenmacher, PhD, Michaela Doering, MD, Tobias Feuchtinger, MD

Blood (2016) 128 (22): 4558.

https://doi.org/10.1182/blood.V128.22.4558.4558

Published: 2016

Journal Articles

WT1-Specific T Cells Exhibiting a Non-Exhausted, Functional Phenotype Can Be Generated From The Natural Repertoire Of Healthy Donors For Clinical Use

Sabine Schmied, MSc, Anne Richter, PhD, Mario Assenmacher, PhD, Juergen Schmitz, PhD

Blood (2013) 122 (21): 4504.

https://doi.org/10.1182/blood.V122.21.4504.4504

Published: 2013

Journal Articles

Virus-Specific T Lymphocytes Maintain Their In Vivo Phenotype and Functional Competence After Automated Processing To Generate a Cellular Product For Immunotherapy

Anne Richter, PhD, Liane Preussner, MD, Verena Traska, Michaela Peters, Ayse Oysal, Katharina Ruhnke, Olaf Brauns, PhD, Sven Kramer, PhD, Juergen Schmitz, PhD, Mario Assenmacher, PhD

Blood (2013) 122 (21): 3268.

https://doi.org/10.1182/blood.V122.21.3268.3268

Published: 2013

Journal Articles

Rapid and Semi-Automated Screening of Multiple Samples for Antigen-Specific T Lymphocytes

Anne Richter, PhD, Michaela Niemöller, Inken Verwohl, Katrin Lange, Anna Foerster-Marniok, Olaf Brauns, PhD, Sven Kramer, PhD, Susanne Höher-Peters, Martin Büscher, PhD, Mario Assenmacher, PhD, Juergen Schmitz, PhD

Blood (2012) 120 (21): 4839.

https://doi.org/10.1182/blood.V120.21.4839.4839

Published: 2012

Journal Articles

Characterization of Peripheral B Cells Expressing CLL-Associated Receptor Tyrosine Kinase ROR1 in Healthy Donors

Julia Milleck, Karl-Anton Kreuzer, Dr. med., Mario Assenmacher, PhD, Jürgen Schmitz, PhD, Peter S Jähn, PhD

Blood (2012) 120 (21): 1787.

https://doi.org/10.1182/blood.V120.21.1787.1787

Published: 2012

Journal Articles

Sensitive Detection of Plasma Cells by Integrated Enrichment in-Column Staining and Analysis

Katja Kühbach, Manuela Herber, Dorothee Koehler, Jürgen Schmitz, PhD, Mario Assenmacher, PhD

Blood (2012) 120 (21): 4968.

https://doi.org/10.1182/blood.V120.21.4968.4968

Published: 2012

Journal Articles

New GMP-Grade, Xeno-Component Free Medium for the Activation and Expansion of T Cells

Mario Assenmacher, Nadine Mockel-Tenbrinck, Alexander Scheffold, Georg Rauser, Hermann Bohnenkamp, Jürgen Schmitz, Uwe Odenthal, Bergendahl Veit, Ulrike Kolrep, Melanie Fahrendorff

Blood (2011) 118 (21): 4316.

https://doi.org/10.1182/blood.V118.21.4316.4316

Published: 2011

Journal Articles

Clinical Scale Central Memory T Cell Enrichment for Adoptive T Cell Therapy

Anna Casati, J\)rgen Schmitz, Hinrich Abken, Markus Chmielewski, Azam Nahvi, Mark Dudley, Mario Assenmacher, Alexander Scheffold

Blood (2010) 116 (21): 5180.

https://doi.org/10.1182/blood.V116.21.5180.5180

Published: 2010

Journal Articles

Clinical Scale Enrichment and Expansion of Highly Pure CD25+Foxp3+ Regulatory T Cells.

Carina Conrads, Jürgen Schmitz, Mario Assenmacher, Claudia Niemand, Alexander Scheffold

Blood (2010) 116 (21): 3718.

https://doi.org/10.1182/blood.V116.21.3718.3718

Published: 2010

Journal Articles

Efficient and Rapid In Vitro Generation of Multi-Virus-Specific CD4 + and CD8 + T Cells for Adoptive Immunotherapy.

Anne Richter, Anna Foerster, Verena Lasmanowicz, Olaf Brauns, Sven Kramer, Petra Jekow, Wolfgang Rönspeck, Mario Assenmacher, Juergen Schmitz

Blood (2010) 116 (21): 1175.

https://doi.org/10.1182/blood.V116.21.1175.1175

Published: 2010

Journal Articles

Automated Generation of Antigen-Specific T Cells for Adoptive T Cell Therapy.

Melanie Fahrendorff, Nanette von Oppen, Georg Rauser, Mario Assenmacher, Juergen Schmitz, Martin Biehl, Stefan Miltenyi

Blood (2010) 116 (21): 1177.

https://doi.org/10.1182/blood.V116.21.1177.1177

Published: 2010

Journal Articles

Adoptive T Cell Therapy of Human CMV Infection in Immunocompromised Hosts: In Vitro Generation of CMV-Specific T Cells from Naïve Precursors

Sonja Schmucker, Mario Assenmacher, Jurgen Schmitz, Anne Richter

Blood (2008) 112 (11): 206.

https://doi.org/10.1182/blood.V112.11.206.206

Published: 2008

Journal Articles

Cytomegalovirus pp65 - Recombinant Protein: A New Antigen for Efficient Restimulation of CD4 + and CD8 + pp65-Specific T Lymphocytes.

Anne Richter, PhD, Patricia Marschall, Marie Mohn, Uwe Odenthal, PhD, Silke Gösling, Manuel Skopnik, Volker Nölle, PhD, Mario Assenmacher, PhD

Blood (2004) 104 (11): 3163.

https://doi.org/10.1182/blood.V104.11.3163.3163

Published: 2004

Journal Articles

Rapid Clinical Scale Isolation of CD25 hi CD4 + Regulatory T Cells.

Claudia Niemand, M.D., Carina Conrads, Ramona Siemer, Mario Assenmacher, Ph.D.

Blood (2004) 104 (11): 4969.

https://doi.org/10.1182/blood.V104.11.4969.4969

Published: 2004

Journal Articles

Rapid generation of combined CMV-specific CD4 + and CD8 + T-cell lines for adoptive transfer into recipients of allogeneic stem cell transplants

Georg Rauser, Hermann Einsele, Christian Sinzger, Dorothee Wernet, Gabriele Kuntz, Mario Assenmacher, John D. M. Campbell, Max S. Topp

Blood (2004) 103 (9): 3565–3572.

https://doi.org/10.1182/blood-2003-09-3056

Published: 2004

NARROW

Characterization and T-Cell Repertoire of MB-CART2019.1 (Zamtocabtagene autoleucel) - Data from the Phase I Trial in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Trial in Progress: A Randomized Phase II Study of MB-CART2019.1 Compared to Standard of Care Therapy in Patients with Relapsed/Refractory DLBCL Ineligible for High-Dose Chemotherapy and Autologous Stem Cell Transplantation - DALY 2-EU Trial

A Phase I Dose Finding Trial of MB-CART20.1 in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

A Phase I Open Label Dose Escalation Study of MB-CART19.1 in Relapsed and Refractory CD19+ B Cell Malignancies, Interim Preliminary Results in Pediatric ALL, Adult ALL Including CLL Cohorts

Defined Central Memory and Stem Memory T Cell Phenotype of CD4 and CD8 CAR T Cells for the Treatment of CD19+ Acute Lymphoblastic Leukemia in an Automated Closed System

WT1-Specific T Cells Exhibiting a Non-Exhausted, Functional Phenotype Can Be Generated From The Natural Repertoire Of Healthy Donors For Clinical Use

Virus-Specific T Lymphocytes Maintain Their In Vivo Phenotype and Functional Competence After Automated Processing To Generate a Cellular Product For Immunotherapy

Rapid and Semi-Automated Screening of Multiple Samples for Antigen-Specific T Lymphocytes

Characterization of Peripheral B Cells Expressing CLL-Associated Receptor Tyrosine Kinase ROR1 in Healthy Donors

Sensitive Detection of Plasma Cells by Integrated Enrichment in-Column Staining and Analysis

New GMP-Grade, Xeno-Component Free Medium for the Activation and Expansion of T Cells

Clinical Scale Central Memory T Cell Enrichment for Adoptive T Cell Therapy

Clinical Scale Enrichment and Expansion of Highly Pure CD25+Foxp3+ Regulatory T Cells.

Efficient and Rapid In Vitro Generation of Multi-Virus-Specific CD4 + and CD8 + T Cells for Adoptive Immunotherapy.

Automated Generation of Antigen-Specific T Cells for Adoptive T Cell Therapy.

Adoptive T Cell Therapy of Human CMV Infection in Immunocompromised Hosts: In Vitro Generation of CMV-Specific T Cells from Naïve Precursors

Cytomegalovirus pp65 - Recombinant Protein: A New Antigen for Efficient Restimulation of CD4 + and CD8 + pp65-Specific T Lymphocytes.

Rapid Clinical Scale Isolation of CD25 hi CD4 + Regulatory T Cells.

Rapid generation of combined CMV-specific CD4 + and CD8 + T-cell lines for adoptive transfer into recipients of allogeneic stem cell transplants

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American Society of Hematology

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ASH Publications

American Society of Hematology

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