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Journal Articles

Integration of ζ -deficient CARs into the CD3 ζ gene conveys potent cytotoxicity in T and NK cells

Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-Garcia, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E. Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-el-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios L. Wagner
Journal: Blood
Blood (2024) 143 (25): 2599–2611.
https://doi.org/10.1182/blood.2023020973
Published: 2024
Includes: Supplemental data
Journal Articles

CAR19 T Cells Redirected to Novel Antigens Mediate Robust Cytotoxicity Against Diverse Malignancies

Paul Rennert, PhD, Christine Ambrose, PhD, Lihe Su, PhD, Fay Dufort, PhD, Lan Wu, PhD, Andreas Hombach, PhD, Hinrich Abken, PhD, Roy Lobb, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4457.
https://doi.org/10.1182/blood.V130.Suppl_1.4457.4457
Published: 2017
Journal Articles

Chimeric antigen receptor T cells targeting Fc μ receptor selectively eliminate CLL cells while sparing healthy B cells

Elena Faitschuk, Andreas A. Hombach, Lukas P. Frenzel, Clemens-Martin Wendtner, Hinrich Abken
Journal: Blood
Blood (2016) 128 (13): 1711–1722.
https://doi.org/10.1182/blood-2016-01-692046
Published: 2016
Journal Articles

Human CD21 low CD86 pos B Cells Are Potent Antigen Presenting Cells, Which Are Expanded in Inflammatory Conditions

Alexander Shimabukuro-Vornhagen, MD, María Alejandra García-Márquez, PhD, Rieke N. Fischer, Juliane Iltgen-Breburda, Anne Fiedler, Kerstin Wennhold, PhD, Gunter Rappl, Hinrich Abken, Pia Hartmann, Clara Lehmann, Thomas Koslowsky, Marco Herling, MD, Dirk Beutner, Dominik Wolf, MD, Gerd Fätkenheuer, Andrea Rubbert-Roth, Michael Hallek, MD, Sebastian Theurich, Michael von Bergwelt-Baildon, Prof. Dr. Dr.
Journal: Blood
Blood (2015) 126 (23): 3432.
https://doi.org/10.1182/blood.V126.23.3432.3432
Published: 2015
Journal Articles

Chimeric Antigen Receptor Transgenic, T Cell Receptor/CD3 Negative Monospecific T Cells Generated from Cord Blood CD34 Positive Cells

Yasmine van Caeneghem, Glenn Goetgeluk, Karin Weening, Greet Verstichel, Sarah Bonte, Tom Taghon, Georges Leclercq, Fritz Offner, Hinrich Abken, Tessa Kerre, MD PhD, Bart Vandekerkhove
Journal: Blood
Blood (2015) 126 (23): 3087.
https://doi.org/10.1182/blood.V126.23.3087.3087
Published: 2015
Journal Articles

Clinical Scale Central Memory T Cell Enrichment for Adoptive T Cell Therapy

Anna Casati, J\)rgen Schmitz, Hinrich Abken, Markus Chmielewski, Azam Nahvi, Mark Dudley, Mario Assenmacher, Alexander Scheffold
Journal: Blood
Blood (2010) 116 (21): 5180.
https://doi.org/10.1182/blood.V116.21.5180.5180
Published: 2010
Journal Articles

CD28 Costimulation of Effector T Cells During An Anti-Tumor Attack Sustains Its Repression by Regulatory T Cells Which Can Be Overcome by Preventing Lck Activation.

David M Kofler, MD, Markus Chmielewski, PhD, Tobias Riet, Andreas Hombach, MD, Michael Hallek, MD, Clemens M Wendtner, MD, Hinrich Abken, MD
Journal: Blood
Blood (2009) 114 (22): 3569.
https://doi.org/10.1182/blood.V114.22.3569.3569
Published: 2009
Journal Articles

Epstein Barr virus–specific cytotoxic T lymphocytes expressing the anti-CD30ζ artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease

Barbara Savoldo, Cliona M. Rooney, Antonio Di Stasi, Hinrich Abken, Andreas Hombach, Aaron E. Foster, Lan Zhang, Helen E. Heslop, Malcolm K. Brenner, Gianpietro Dotti
Journal: Blood
Blood (2007) 110 (7): 2620–2630.
https://doi.org/10.1182/blood-2006-11-059139
Published: 2007
Includes: Supplemental data
Journal Articles

Impact of Regulatory T Cells on Antigen Specific T Cell Response Using Recombinant Chimeric T Cell Receptors In Vivo.

David M. Kofler, MD, Markus Chmielewski, Heike Koehler, Tobias Riet, Patrick Schmidt, Gunter Rappl, Andreas Hombach, MD, Michael Hallek, MD, Clemens M. Wendtner, MD, Hinrich Abken, MD
Journal: Blood
Blood (2006) 108 (11): 5475.
https://doi.org/10.1182/blood.V108.11.5475.5475
Published: 2006
Journal Articles

XIAP targeting sensitizes Hodgkin lymphoma cells for cytolytic T-cell attack

Hamid Kashkar, Jens-Michael Seeger, Andreas Hombach, Anke Deggerich, Benjamin Yazdanpanah, Olaf Utermöhlen, Gerd Heimlich, Hinrich Abken, Martin Krönke
Journal: Blood
Blood (2006) 108 (10): 3434–3440.
https://doi.org/10.1182/blood-2006-05-021675
Published: 2006