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Journal Articles

New Suitable Eµ-Tcl1 Mouse Model for Research on BH3-Mimetics Therapy Response In Vivo

Ismini Halmer, Laura Beckmann, Gero Knittel, Hamid Kashkar, Hans Christian Reinhardt, Michael Hallek, Alexandra Da Palma Guerreiro, Lukas Peter Frenzel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1454.
https://doi.org/10.1182/blood-2023-186330
Published: 2023
Journal Articles

Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma

Grace M. Pindzola, Raud Razzaghi, Rachel N. Tavory, Hang T. Nguyen, Vivian M. Morris, Moyi Li, Shreya Agarwal, Bonnie Huang, Takaharu Okada, Hans C. Reinhardt, Gero Knittel, Hamid Kashkar, Ryan M. Young, Stefania Pittaluga, Jagan R. Muppidi
Journal: Blood
Blood (2022) 140 (10): 1119–1131.
https://doi.org/10.1182/blood.2022015926
Published: 2022
Includes: Supplemental data
Journal Articles

A Novel BCL2-Driven Compound Mutant Mouse Model for In Vivo Research on BH3 Mimetics

Ismini Halmer, Alexandra da Palma Guerreiro, PhD, Laura Beckmann, MD, Christian Reinhardt, MD, Hamid Kashkar, Michael Hallek, Lukas P. Frenzel, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39.
https://doi.org/10.1182/blood-2020-142569
Published: 2020
Journal Articles

B-cell–specific conditional expression of Myd88 p.L252P leads to the development of diffuse large B-cell lymphoma in mice

Gero Knittel, Paul Liedgens, Darya Korovkina, Jens M. Seeger, Yussor Al-Baldawi, Mona Al-Maarri, Christian Fritz, Katerina Vlantis, Svetlana Bezhanova, Andreas H. Scheel, Olaf-Oliver Wolz, Maurice Reimann, Peter Möller, Cristina López, Matthias Schlesner, Philipp Lohneis, Alexander N. R. Weber, Lorenz Trümper, German International Cancer Genome Consortium Molecular Mechanisms in Malignant Lymphoma by Sequencing Project Consortium, Louis M. Staudt, Monika Ortmann, Manolis Pasparakis, Reiner Siebert, Clemens A. Schmitt, Andreas R. Klatt, F. Thomas Wunderlich, Stephan C. Schäfer, Thorsten Persigehl, Manuel Montesinos-Rongen, Margarete Odenthal, Reinhard Büttner, Lukas P. Frenzel, Hamid Kashkar, H. Christian Reinhardt
Journal: Blood
Blood (2016) 127 (22): 2732–2741.
https://doi.org/10.1182/blood-2015-11-684183
Published: 2016
Includes: Supplemental data
Journal Articles

p38 MAPK Controls Sensitivity Towards BH3 Mimetics By Regulating Mcl-1 Expression of Chronic Lymphocytic Leukemia in Hypoxia and Acquired Resistance

Malte F Huelsemann, Michaela Patz, PhD, Laura Beckmann, Kerstin Brinkmann, Teresa Otto, Joachim Fandrey, MD, Hans Jiro Becker, Sebastian Theurich, MD, Michael S. von Bergwelt-Baildon, MD PhD, Christian P. Pallasch, MD, Réne P. Zahedi, Hamid Kashkar, PhD, Christian Reinhardt, MD, Michael Hallek, MD, Clemens-Martin Wendtner, MD, Lukas P. Frenzel, MD
Journal: Blood
Blood (2014) 124 (21): 1947.
https://doi.org/10.1182/blood.V124.21.1947.1947
Published: 2014
Journal Articles

TOSO Deficiency Exerts Impact On BAFF-R Expression, Thereby Causing Impaired B Cell Development in Vivo

Alexandra Schulz, PhD, Yoon Jung Park, Ph.D., Rainer Claus, MD, Hamid Kashkar, PhD, Jens Seeger, PhD, Julia Claasen, Christian P. Pallasch, MD, Christoph Plass, PhD, Michael Hallek, MD, Clemens Wendtner, Lukas P. Frenzel, MD
Journal: Blood
Blood (2012) 120 (21): 3898.
https://doi.org/10.1182/blood.V120.21.3898.3898
Published: 2012
Journal Articles

Novel X-Linked Inhibitor of Apoptosis (XIAP) Inhibiting Compound as Sensitizer for TRAIL-Mediated Apoptosis In Chronic Lymphocytic Leukemia with Poor Prognosis

Lukas P. Frenzel, MD, Michaela Patz, PhD, Christian P. Pallasch, MD, Reinhild Brinker, Julia Claasen, Alexandra Schulz, Michael Hallek, MD, Hamid Kashkar, PhD, Clemens-Martin Wendtner, MD
Journal: Blood
Blood (2010) 116 (21): 1375.
https://doi.org/10.1182/blood.V116.21.1375.1375
Published: 2010
Journal Articles

Overexpression of TOSO in CLL Is Triggered by B-Cell Receptor Signaling and Associated with Progressive Disease.

Christian P Pallasch, MD, Alexandra Schulz, Nadine Kutsch, Janine Schwamb, Susanne Hagist, MD, Claudia Wickenhauser, MD, Alfred Ultsch, PhD, Hamid Kashkar, PhD, Michael Hallek, MD, Clemens-Martin Wendtner, MD
Journal: Blood
Blood (2008) 112 (11): 2070.
https://doi.org/10.1182/blood.V112.11.2070.2070
Published: 2008
Journal Articles

Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease

Christian Philipp Pallasch, Alexandra Schulz, Nadine Kutsch, Janine Schwamb, Susanne Hagist, Hamid Kashkar, Alfred Ultsch, Claudia Wickenhauser, Michael Hallek, Clemens-Martin Wendtner
Journal: Blood
Blood (2008) 112 (10): 4213–4219.
https://doi.org/10.1182/blood-2008-05-157255
Published: 2008
Includes: Supplemental data
Journal Articles

NF-κB–independent down-regulation of XIAP by bortezomib sensitizes HL B cells against cytotoxic drugs

Hamid Kashkar, Anke Deggerich, Jens-Michael Seeger, Benjamin Yazdanpanah, Katja Wiegmann, Dirk Haubert, Carola Pongratz, Martin Krönke
Journal: Blood
Blood (2006) 109 (9): 3982–3988.
https://doi.org/10.1182/blood-2006-10-053959
Published: 2006
Journal Articles

XIAP targeting sensitizes Hodgkin lymphoma cells for cytolytic T-cell attack

Hamid Kashkar, Jens-Michael Seeger, Andreas Hombach, Anke Deggerich, Benjamin Yazdanpanah, Olaf Utermöhlen, Gerd Heimlich, Hinrich Abken, Martin Krönke
Journal: Blood
Blood (2006) 108 (10): 3434–3440.
https://doi.org/10.1182/blood-2006-05-021675
Published: 2006