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Mark T. Gladwin, MD
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Journal Articles

Impaired Hepcidin Metabolism Promotes Hemolysis Induced Hepatobiliary Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Prithu Sundd, PhD, Mark T Gladwin, MD, Tirthadipa Pradhan
Journal: Blood
Blood (2020) 136 (Supplement 1): 28.
https://doi.org/10.1182/blood-2020-143357
Published: 2020
Journal Articles

Exercise Induced Changes of Vital Signs in Adults with Sickle Cell Disease

Solomon Johnson, MS, Victor R. Gordeuk, MD, Roberto Machado, MD, J Simon R Gibbs, Mariana Hildesheim, MS, Jane A. Little, MD, Gregory J Kato, MD, Mark T Gladwin, MD, Seyed Mehdi Nouraie, PhD MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 59–60.
https://doi.org/10.1182/blood-2020-136393
Published: 2020
Journal Articles

The T117S Variant of Cytochrome b5 Reductase 3 Increases the Risk for Ischemic Stroke with Enhanced Anemia in Mice with Sickle Cell Disease

Katherine C Wood, PhD, Heidi M Schmidt, Scott Hahn, MS, Subramaniam Sanker, PhD, Samit Ghosh, PhD, Solomon Fiifi Ofori-Acquah, PhD, Seyed Mehdi Nouraie, MD PhD, Mark T Gladwin, MD, Adam C Straub, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-142076
Published: 2020
Journal Articles

Integrin αIIbβ3 Regulates Platelet-Procoagulant Activity in the Lung

Tomasz Brzoska, PhD, Tomasz W. Kaminski, PharmD, Ravi Vats, MSc, Egemen Tutuncuoglu, MSc, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32.
https://doi.org/10.1182/blood-2020-142503
Published: 2020
Journal Articles

Genome Wide Association Analysis of Iron Overload in the Trans-Omics for Precision Medicine (TOPMed) Sickle Cell Disease Cohorts

Fayuan Wen, PhD, Angela Rock, Juan Salomon-Andonie, MS, Gulriz Kurban, PhD, Xiaomei Niu, MD, Songping Wang, Xu Zhang, PhD, Victor R. Gordeuk, MD, Yingze Zhang, PhD, Seyed Mehdi Nouraie, PhD MD, Mark T Gladwin, MD, Allison Ashley-Koch, PhD, Marilyn J. Telen, MD, Brian Custer, PhD, Shannon Kelly, Carla Luana Dinardo, PhD, Ester Sabino, Quenna Wong, James G. Taylor, MD, Sergei Nekhai, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-142809
Published: 2020
Journal Articles

Loss of FXR Signaling Promotes Chronic Liver Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Mark T Gladwin, MD, Prithu Sundd, PhD, Tirthadipa Pradhan
Journal: Blood
Blood (2020) 136 (Supplement 1): 16.
https://doi.org/10.1182/blood-2020-143330
Published: 2020
Journal Articles

Evaluation of the Functional Effects of an African American Glucose-6-Phosphate Dehydrogenase (G6PD) Polymorphism (Val68Met) on RBC Hemolytic Propensity and Post-Transfusion Recovery in a Humanized Mouse Model

Ling Wang, MD PhD, Benjamin Zuchelkowski, Derek Sinchar, Minying Yang, Sebastien Gingras, Tamir Kanias, PhD, Janet S Lee, Daniel Kim-Shapiro, Grier Page, PhD BS, MS, Mark T Gladwin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 102.
https://doi.org/10.1182/blood-2019-124926
Published: 2019
Journal Articles

Innate Immune Mechanism of Hemarthrosis in Hemophilia-a Mice

Tomasz W. Kaminski, PharmD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1043.
https://doi.org/10.1182/blood-2019-130471
Published: 2019
Journal Articles

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Stevan P. Tofovic, Edwin K. Jackson, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2266.
https://doi.org/10.1182/blood-2019-130882
Published: 2019
Journal Articles

Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia

Santosh L. Saraf, MD, Vimal K. Derebail, MD, Xu Zhang, PhD, Mark T Gladwin, MD, Victor R Gordeuk, MD, Jane A. Little, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2268.
https://doi.org/10.1182/blood-2019-124737
Published: 2019
Journal Articles

Risk Factors for Kidney Disease in Hb SC and Hb Sβ + -Thalassemia Sickle Cell Disease

Mandella Mensah, Binal N. Shah, Xu Zhang, PhD, Jin Han, PharmD, PhD, Michel Gowhari, DO, Robert E. Molokie, MD, Mark T Gladwin, MD, Victor R Gordeuk, MD, Santosh L. Saraf, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2299.
https://doi.org/10.1182/blood-2019-128668
Published: 2019
Journal Articles

Circulating Neutrophil Extracellular Traps in the Pathogenesis of Acute Chest Syndrome of Sickle Cell Disease

Ravi Vats, MSc, Egemen Tutuncuoglu, MSc, Jesus Tejero, PhD, Cheryl A Hillery, MD, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3556.
https://doi.org/10.1182/blood-2019-130574
Published: 2019
Journal Articles

Smooth Muscle Cytochrome b5 Reductase 3 Deficiency Accelerates Pulmonary Hypertension Development in Sickle Cell Mice

Katherine Wood, PhD BA, Brittany Durgin, PhD, Heidi M Schmidt, BSE, Scott Hahn, Jeffrey Baust, Tim Bachman, Dario A. Vitturi, PhD, Samit Ghosh, Solomon Fiifi Ofori-Acquah, Ana Mora, MD, Mark T Gladwin, MD, Adam Straub, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3619.
https://doi.org/10.1182/blood-2019-124159
Published: 2019
Journal Articles

Impaired Bile Secretion Promotes Chronic Liver Injury in Sickle Cell Disease

Tirthadipa Pradhan, Prithu Sundd, PhD, Mark T Gladwin, MD, Satdarshan Pal Monga, Gregory J Kato, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3536.
https://doi.org/10.1182/blood-2019-131915
Published: 2019
Journal Articles

Mechanism of Pulmonary Thrombosis in Hemolytic Disorders

Tomasz Brzoska, PhD, Margaret F. Bennewitz, PhD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Matthew D Neal, MD, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 976.
https://doi.org/10.1182/blood-2019-130592
Published: 2019
Journal Articles

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Tirthadipa Pradhan, Prithu Sundd, PhD, Satdarshan Pal Monga, Mark T Gladwin, MD, Gregory J Kato, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 958.
https://doi.org/10.1182/blood-2019-131921
Published: 2019
Journal Articles

Clinical and Laboratory Predictors of 30-Day Hospital Readmission Risk in Adult Patients with Sickle Cell Disease

Seyed Mehdi Nouraie, PhD MD, Melissa Saul, MS, Enrico M Novelli, MD MS, Gregory J. Kato, MD, Mark T Gladwin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2384.
https://doi.org/10.1182/blood-2018-99-115248
Published: 2018
Journal Articles

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Bin Sun, PhD, Valerie Miller, MS, Karin P Potoka, MD, Yukio Nakamura, MD PhD, Mark T Gladwin, MD, Grant C. Bullock, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1060.
https://doi.org/10.1182/blood-2018-99-120306
Published: 2018
Journal Articles

Regulatory Genetic Variation at the S100B Gene Associates with Vaso-Occlusive Manifestations in Sickle Cell Disease

Xu Zhang, PhD, Wei Zhang, PhD, Santosh L. Saraf, MD, Sergei Nekhai, PhD, Mark T Gladwin, MD, Roberto Machado, Victor R. Gordeuk, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1063.
https://doi.org/10.1182/blood-2018-99-115395
Published: 2018
Journal Articles

Reduced Hemolysis and Related Complications in Females with Sickle Cell Disease

Santosh L. Saraf, MD, Tamir Kanias, PhD, Xu Zhang, PhD, Binal Shah, PhD, Rasha Raslan, MD, Jin Han, PharmD, PhD, Roberto F. Machado, MD, Mark T Gladwin, MD, Victor R. Gordeuk, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3530.
https://doi.org/10.1182/blood.V130.Suppl_1.3530.3530
Published: 2017