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Tirthadipa Pradhan
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Journal Articles

Hemolysis Induced Induction of Matrix Metalloproteinases in Sickle Cell Disease

Taylor Michelle Leslie, Tirthadipa Pradhan-Sundd
Journal: Blood
Blood (2023) 142 (Supplement 1): 5284.
https://doi.org/10.1182/blood-2023-187571
Published: 2023
Journal Articles

Hemoglobin Receptor CD163 As a Potential Biomarker of Hemolysis Induced Hepatobiliary Injury in Sickle Cell Disease

Ramakrishna Ungalara, Omika Katoch, Tomasz Waldemar Kaminski, Tirthadipa Pradhan-Sundd
Journal: Blood
Blood (2023) 142 (Supplement 1): 3863.
https://doi.org/10.1182/blood-2023-188046
Published: 2023
Journal Articles

Impaired Hemoglobin Clearance By Liver Sinusoidal Endothelium Promotes Liver Damage in Sickle Cell Disease

Ziming Li, Omika Katoch, Ramakrishna Ungalara, Tirthadipa Pradhan-Sundd
Journal: Blood
Blood (2023) 142 (Supplement 1): 1119.
https://doi.org/10.1182/blood-2023-187916
Published: 2023
Journal Articles

Sec14-like-Lipid-Binding-4 Enables Hemoglobin Clearance By Liver Sinusoidal Endothelial Cells

Tirthadipa Pradhan-Sundd, Elizabeth R Rochon, Omika Katoch, Rikesh K. Dubey, Derek J Sinchar, Ling Wang, Prithu Sundd, Mark T. Gladwin
Journal: Blood
Blood (2022) 140 (Supplement 1): 8553.
https://doi.org/10.1182/blood-2022-170805
Published: 2022
Journal Articles

Myeloid Specific HO-1-SIRT1-p53 Nexus Protects Against Iron Induced Chronic Liver Injury in Sickle Cell Disease

Omika Katoch, Ziming Li, Ravi Vats, Rikesh K. Dubey, Tomasz W. Kaminski, Tomasz Brzoska, Prithu Sundd, Enrico M. Novelli, Tirthadipa Pradhan-Sundd
Journal: Blood
Blood (2022) 140 (Supplement 1): 8251.
https://doi.org/10.1182/blood-2022-170095
Published: 2022
Journal Articles

Notch Pathway Driven Delayed Dedifferentiation of Liver Sinusoidal Endothelium Impacts Liver-Directed Gene Transfer in Hemophilia-a Mice

Tirthadipa Pradhan-Sundd, Tomasz W. Kaminski, Rikesh K.K. Dubey, Shweta Gudapati, Omika Katoch, Jesús Tejero, Enrico M. Novelli, Margaret V. Ragni, Prithu Sundd
Journal: Blood
Blood (2022) 140 (Supplement 1): 10658–10659.
https://doi.org/10.1182/blood-2022-170050
Published: 2022
Journal Articles

Liver-to-lung microembolic NETs promote gasdermin D–dependent inflammatory lung injury in sickle cell disease

Ravi Vats, Tomasz W. Kaminski, Tomasz Brzoska, John A. Leech, Egemen Tutuncuoglu, Omika Katoch, Jude Jonassaint, Jesus Tejero, Enrico M. Novelli, Tirthadipa Pradhan-Sundd, Mark T. Gladwin, Prithu Sundd
Journal: Blood
Blood (2022) 140 (9): 1020–1037.
https://doi.org/10.1182/blood.2021014552
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

A Dedifferentiated Sinusoidal Endothelium Impacts Liver-Directed Gene Transfer in Hemophilia-a Mice

Shweta Gudapati, Tomasz W. Kaminski, Ravi Vats, Prithu Sundd, Tirthadipa Pradhan-Sundd
Journal: Blood
Blood (2021) 138 (Supplement 1): 3981.
https://doi.org/10.1182/blood-2021-152905
Published: 2021
Journal Articles

P-Selectin Deficiency in Sickle Cell Disease Mice Leads to Senescence Induced Organ Injury

Ravi Vats, Tomasz W. Kaminski, Shweta Gudapati, Tomasz Brzoska, Prithu Sundd, Tirthadipa Pradhan-Sundd
Journal: Blood
Blood (2021) 138 (Supplement 1): 4165.
https://doi.org/10.1182/blood-2021-152707
Published: 2021
Journal Articles

P-selectin deficiency promotes liver senescence in sickle cell disease mice

Brief Report
Ravi Vats, Tomasz W. Kaminski, Eun-Mi Ju, Tomasz Brozska, Egemen Tutuncuoglu, Jesús Tejero, Enrico M. Novelli, Prithu Sundd, Tirthadipa Pradhan-Sundd
Journal: Blood
Blood (2021) 137 (19): 2676–2680.
https://doi.org/10.1182/blood.2020009779
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Impaired Hepcidin Metabolism Promotes Hemolysis Induced Hepatobiliary Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Prithu Sundd, PhD, Mark T Gladwin, MD, Tirthadipa Pradhan
Journal: Blood
Blood (2020) 136 (Supplement 1): 28.
https://doi.org/10.1182/blood-2020-143357
Published: 2020
Journal Articles

Loss of FXR Signaling Promotes Chronic Liver Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Mark T Gladwin, MD, Prithu Sundd, PhD, Tirthadipa Pradhan
Journal: Blood
Blood (2020) 136 (Supplement 1): 16.
https://doi.org/10.1182/blood-2020-143330
Published: 2020
Journal Articles

Impaired Bile Secretion Promotes Chronic Liver Injury in Sickle Cell Disease

Tirthadipa Pradhan, Prithu Sundd, PhD, Mark T Gladwin, MD, Satdarshan Pal Monga, Gregory J Kato, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3536.
https://doi.org/10.1182/blood-2019-131915
Published: 2019
Journal Articles

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Tirthadipa Pradhan, Prithu Sundd, PhD, Satdarshan Pal Monga, Mark T Gladwin, MD, Gregory J Kato, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 958.
https://doi.org/10.1182/blood-2019-131921
Published: 2019
Journal Articles

Molecular Mechanism of Intrahepatic Cholestasis in Sickle Cell Disease

Tirthadipa Pradhan, PhD, Prithu Sundd, Egemen Tutuncuoglu, MSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 4775.
https://doi.org/10.1182/blood.V130.Suppl_1.4775.4775
Published: 2017