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Journal Articles

Interleukin-27 ameliorates inflammation-induced chronic pain in sickle cell disease

Adekunle Alagbe, Lynda Little-Ihrig, Michael Gold, Prithu Sundd, Enrico Novelli

Blood (2025) 146 (Supplement 1): 4709.

https://doi.org/10.1182/blood-2025-4709

Published: 2025

Journal Articles

Dual complement and P-selectin inhibitor, IHP-102, prevents lung vaso-occlusion in P-selectin-deficient townes SS mice

John Paderi, Rikesh Dubey, Tomasz Kaminski, Fnu Manikanta, Prithu Sundd

Blood (2025) 146 (Supplement 1): 4707.

https://doi.org/10.1182/blood-2025-4707

Published: 2025

Journal Articles

Neutrophil-TLR9 is a therapeutic target for acute chest syndrome in sickle cell disease

Ayyanar Sivanantham, Shane Howe, Nicholas Swendrowski, Joshua Field, Prithu Sundd

Blood (2025) 146 (Supplement 1): 839.

https://doi.org/10.1182/blood-2025-839

Published: 2025

Journal Articles

G-CSF receptor is a signaling node linking thrombo-inflammation to vaso-occlusion in sickle cell disease: Target for a new phase 2 trial

Gregory Kato, Tomasz Kaminski, Paolo Rossato, Fnu Manikanta, Nicholas Swendrowski, Nicole Westerfeld, Arne Wehling, Carlos Roca, Steffi Knoll Machado, Timo Kraushaar, Branislav Krljanac, Fuad Abdulla, Julia Nguyen, Chunsheng Chen, Conglin Ruan, Markus Brechmann, Gregory Vercellotti, Prithu Sundd, John Belcher

Blood (2025) 146 (Supplement 1): 838.

https://doi.org/10.1182/blood-2025-838

Published: 2025

Journal Articles

Platelet RIG-I Promotes Flu-Induced Severe Lung Injury in Sickle Cell Disease

Tomasz Kaminski, Nicholas Swendrowski, Omika Katoch, Prithu Sundd

Blood (2024) 144 (Supplement 1): 1102.

https://doi.org/10.1182/blood-2024-211030

Published: 2024

Journal Articles

DNA Sensing By Platelets Promotes Acute Chest Syndrome in Sickle Cell Disease

Rikesh K Dubey, Omika Katoch, Nicholas Swendrowski, Prithu Sundd

Blood (2024) 144 (Supplement 1): 2493.

https://doi.org/10.1182/blood-2024-211203

Published: 2024

Journal Articles

Circulating Extracellular Vesicles Enable IFN-I Response in Neutrophils of Sickle Cell Disease Mice

Ayyanar Sivanantham, Omika Katoch, Nicholas Swendrowski, Prithu Sundd

Blood (2024) 144 (Supplement 1): 1100.

https://doi.org/10.1182/blood-2024-204433

Published: 2024

Journal Articles

αIIbβ3-Dependent Platelet Procoagulant Activity Promotes Pulmonary Arterial Thrombosis Triggered By Blood-Borne Tissue Factor

Sarah E. Tashbook, Tomasz W. Kaminski, Prithu Sundd, Tomasz Brzoska

Blood (2024) 144 (Supplement 1): 2607.

https://doi.org/10.1182/blood-2024-205702

Published: 2024

Journal Articles

Clearance of Sickle Hemoglobin By Hepatic Endothelial Cells Is Critical to Protect Against Hemolysis Induced Organ Damage in Sickle Cell Anemia

Tomasz Kaminski, Omika Katoch, Ziming Li, Prithu Sundd, Tirthadipa Pradhan-Sundd

Blood (2024) 144 (Supplement 1): 5290.

https://doi.org/10.1182/blood-2024-211134

Published: 2024

Journal Articles

Neutrophil-Dependent Interferonopathy Promotes Hemophilic Arthropathy

Tomasz Kaminski, Omika Katoch, Margaret V. Ragni, Prithu Sundd

Blood (2024) 144 (Supplement 1): 432.

https://doi.org/10.1182/blood-2024-211163

Published: 2024

Journal Articles

Neutrophil-Dependent Immune Response Promotes Joint Damage in Hemophilia

Tomasz Waldemar Kaminski, Omika Katoch, Margaret V. Ragni, Prithu Sundd

Blood (2023) 142 (Supplement 1): 5351.

https://doi.org/10.1182/blood-2023-190711

Published: 2023

Journal Articles

Circulating NETs Promote Platelet-TLR9 Dependent Acute Chest Syndrome in Sickle Cell Disease

Rikesh K Dubey, Omika Katoch, Enrico M Novelli, Prithu Sundd

Blood (2023) 142 (Supplement 1): 1121.

https://doi.org/10.1182/blood-2023-187381

Published: 2023

Journal Articles

Flu Induced Acute Chest Syndrome in Sickle Cell Disease Mice

Tomasz Waldemar Kaminski, Omika Katoch, Prithu Sundd

Blood (2023) 142 (Supplement 1): 2479.

https://doi.org/10.1182/blood-2023-190673

Published: 2023

Journal Articles

Dual P-Selectin and Complement Inhibition with Subcutaneous IHP-102 Treatment Potently Reduces Lung Vaso-Occlusion in Sickle Cell Disease Mice

John Paderi, Rikesh K Dubey, Gabriel Njikang, Prithu Sundd

Blood (2023) 142 (Supplement 1): 1122.

https://doi.org/10.1182/blood-2023-174796

Published: 2023

Journal Articles

IL-27 Promotes Neutrophil Extracellular Trap Generation in Sickle Cell Disease

Adekunle Emmanuel Alagbe, Enrico M Novelli, Prithu Sundd

Blood (2023) 142 (Supplement 1): 5283.

https://doi.org/10.1182/blood-2023-189264

Published: 2023

Journal Articles

Endothelial Extracellular Vesicles Regulate Platelet Purinergic Signaling in Sickle Cell Disease

Tomasz Brzoska, Elizaveta V Menchikova, Tomasz W. Kaminski, Stevan P. Tofovic, Edwin K. Jackson, Prithu Sundd

Blood (2022) 140 (Supplement 1): 5532.

https://doi.org/10.1182/blood-2022-167448

Published: 2022

Journal Articles

Myeloid Specific HO-1-SIRT1-p53 Nexus Protects Against Iron Induced Chronic Liver Injury in Sickle Cell Disease

Omika Katoch, Ziming Li, Ravi Vats, Rikesh K. Dubey, Tomasz W. Kaminski, Tomasz Brzoska, Prithu Sundd, Enrico M. Novelli, Tirthadipa Pradhan-Sundd

Blood (2022) 140 (Supplement 1): 8251.

https://doi.org/10.1182/blood-2022-170095

Published: 2022

Journal Articles

Notch Pathway Driven Delayed Dedifferentiation of Liver Sinusoidal Endothelium Impacts Liver-Directed Gene Transfer in Hemophilia-a Mice

Tirthadipa Pradhan-Sundd, Tomasz W. Kaminski, Rikesh K.K. Dubey, Shweta Gudapati, Omika Katoch, Jesús Tejero, Enrico M. Novelli, Margaret V. Ragni, Prithu Sundd

Blood (2022) 140 (Supplement 1): 10658–10659.

https://doi.org/10.1182/blood-2022-170050

Published: 2022

Journal Articles

Platelet TLR9 Promotes Pulmonary Thrombo-Inflammation in Sickle Cell Disease

Rikesh K.K. Dubey, Tomasz W. Kaminski, Tomasz Brzoska, Omika Katoch, Prithu Sundd

Blood (2022) 140 (Supplement 1): 11095.

https://doi.org/10.1182/blood-2022-169715

Published: 2022

Journal Articles

Sec14-like-Lipid-Binding-4 Enables Hemoglobin Clearance By Liver Sinusoidal Endothelial Cells

Tirthadipa Pradhan-Sundd, Elizabeth R Rochon, Omika Katoch, Rikesh K. Dubey, Derek J Sinchar, Ling Wang, Prithu Sundd, Mark T. Gladwin

Blood (2022) 140 (Supplement 1): 8553.

https://doi.org/10.1182/blood-2022-170805

Published: 2022

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Interleukin-27 ameliorates inflammation-induced chronic pain in sickle cell disease

Dual complement and P-selectin inhibitor, IHP-102, prevents lung vaso-occlusion in P-selectin-deficient townes SS mice

Neutrophil-TLR9 is a therapeutic target for acute chest syndrome in sickle cell disease

G-CSF receptor is a signaling node linking thrombo-inflammation to vaso-occlusion in sickle cell disease: Target for a new phase 2 trial

Platelet RIG-I Promotes Flu-Induced Severe Lung Injury in Sickle Cell Disease

DNA Sensing By Platelets Promotes Acute Chest Syndrome in Sickle Cell Disease

Circulating Extracellular Vesicles Enable IFN-I Response in Neutrophils of Sickle Cell Disease Mice

αIIbβ3-Dependent Platelet Procoagulant Activity Promotes Pulmonary Arterial Thrombosis Triggered By Blood-Borne Tissue Factor

Clearance of Sickle Hemoglobin By Hepatic Endothelial Cells Is Critical to Protect Against Hemolysis Induced Organ Damage in Sickle Cell Anemia

Neutrophil-Dependent Interferonopathy Promotes Hemophilic Arthropathy

Neutrophil-Dependent Immune Response Promotes Joint Damage in Hemophilia

Circulating NETs Promote Platelet-TLR9 Dependent Acute Chest Syndrome in Sickle Cell Disease

Flu Induced Acute Chest Syndrome in Sickle Cell Disease Mice

Dual P-Selectin and Complement Inhibition with Subcutaneous IHP-102 Treatment Potently Reduces Lung Vaso-Occlusion in Sickle Cell Disease Mice

IL-27 Promotes Neutrophil Extracellular Trap Generation in Sickle Cell Disease

Endothelial Extracellular Vesicles Regulate Platelet Purinergic Signaling in Sickle Cell Disease

Myeloid Specific HO-1-SIRT1-p53 Nexus Protects Against Iron Induced Chronic Liver Injury in Sickle Cell Disease

Notch Pathway Driven Delayed Dedifferentiation of Liver Sinusoidal Endothelium Impacts Liver-Directed Gene Transfer in Hemophilia-a Mice

Platelet TLR9 Promotes Pulmonary Thrombo-Inflammation in Sickle Cell Disease

Sec14-like-Lipid-Binding-4 Enables Hemoglobin Clearance By Liver Sinusoidal Endothelial Cells

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