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Marlene Balys
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Journal Articles

Adipose Tissue Functions As a Reservoir for Leukemia Stem Cells and Confers Chemo-Resistance

Free
Haobin Ye, Biniam Adane, Nabilah Khan, PhD, John M. Ashton, PhD, Marlene Balys, Brett M Stevens, PhD, Mohammad Minhajuddin, Craig T Jordan, PhD
Journal: Blood
Blood (2015) 126 (23): 845.
https://doi.org/10.1182/blood.V126.23.845.845
Published: 2015
Journal Articles

Leukemia Cells Resident in Adipose Tissue Display a Pro-Inflammatory Phenotype and Induce Lipolysis and Atrophy of Adipose Tissue

Free
Haobin Ye, Nabilah Khan, PhD, Marlene Balys, John M. Ashton, PhD, Biniam Adane, Craig T Jordan, PhD
Journal: Blood
Blood (2015) 126 (23): 2765.
https://doi.org/10.1182/blood.V126.23.2765.2765
Published: 2015
Journal Articles

Distinct Properties of Leukemia Stem Cells in Primary Refractory Acute Myeloid Leukemia

Free
Jason H. Mendler, MD PhD, Marlene Balys, Umayal Sivagnanalingam, Allison Eberhardt, Korinne Thorne, Tzu-Chieh Ho, PhD, Mark W. LaMere, BA, Samuel Moore, Helene McMurray, PhD, Jason R. Myers, John M. Ashton, PhD, Kristen O'Dwyer, MD, Jane L. Liesveld, MD, Laura M. Calvi, MD, Michael W. Becker, MD
Journal: Blood
Blood (2015) 126 (23): 685.
https://doi.org/10.1182/blood.V126.23.685.685
Published: 2015
Journal Articles

A Novel Xenograft Model of Cytogenetically Normal Acute Myeloid Leukemia Harboring RUNX1 and ASXL1 Mutations Demonstrates Residual Disease after Anthracycline/Cytarabine-Based Chemotherapy

Free
Umayal Sivagnanalingam, BS, Marlene Balys, Allison Eberhardt, Nancy Wang, PhD, John M. Ashton, PhD, Jason H. Mendler, MD PhD
Journal: Blood
Blood (2014) 124 (21): 9.
https://doi.org/10.1182/blood.V124.21.9.9
Published: 2014
Journal Articles

Rocaglamide Selectively Eradicates Human Leukemia Stem Cells and Synergizes with Multiple Agents to Target AML Cells

Free
Kevin P Callahan, PhD, Cheryl Corbett, Steven Jacob, Mohammad Minhajuddin, PhD, Eleni D Lagadinou, MD/PhD, Randall M Rossi, MS, Valerie Gross, Marlene Balys, Fred Hagen, PhD, Alison J Frontier, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2012) 120 (21): 1338.
https://doi.org/10.1182/blood.V120.21.1338.1338
Published: 2012
Journal Articles

Oncogene Cooperativity Analysis Reveals a Novel Set of Genes That Regulate the In Vivo Growth and Survival of Leukemia Stem Cells

Free
John M Ashton, Marlene Balys, Sarah Neering, Glenn Cowley, PhD, David E. Root, PhD, Peter G. Miller, PhD, Benjamin Ebert, MD, Helene McMurray, PhD, Duane C Hassane, PhD, Hartmut Land, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2011) 118 (21): 553.
https://doi.org/10.1182/blood.V118.21.553.553
Published: 2011
Journal Articles

Reactive Oxygen Species (ROS) Levels Define Functional Heterogeneity in Human Leukemia Stem Cells and Represent a Critical Parameter for Therapeutic Targeting

Free
Eleni Lagadinou, MD/PhD, Kevin Callahan, PhD, Sarah J Neering, BS, ShanShan Pei, BS, Mohammad Minhajuddin, PhD, Randall M Rossi, MS, Valerie Grose, BS, Cheryl Corbett, Marlene Balys, BS, Paul Brookes, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2011) 118 (21): 639.
https://doi.org/10.1182/blood.V118.21.639.639
Published: 2011
Journal Articles

Molecular Mechanisms of Parthenolide-Mediated Pro-Apoptotic Activity in Acute Myeloid Leukemia Cells

Free
Mohammad Minhajuddin, PhD, Shanshan Pei, John M Ashton, Kevin Callahan, PhD, Eleni Lagadinou, MD/PhD, Marlene Balys, Cheryl Corbett, Sarah Neering, Randall M Rossi, MS, Craig T. Jordan, PhD
Journal: Blood
Blood (2011) 118 (21): 2463.
https://doi.org/10.1182/blood.V118.21.2463.2463
Published: 2011
Journal Articles

Targeting Redox Homeostasis As a Means to Selectively Eradicate Primary Human Leukemia Cells,

Free
Shanshan Pei, Kevin Callahan, PhD, Mohammad Minhajuddin, PhD, Marlene Balys, Sarah Neering, Cheryl Corbett, Michael W. Becker, MD, Jane L. Liesveld, MD, Fred Hagen, PhD, Alan E Friedman, PhD, Peter Crooks, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2011) 118 (21): 3506.
https://doi.org/10.1182/blood.V118.21.3506.3506
Published: 2011
Journal Articles

Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways

Free
Duane C. Hassane, Siddhartha Sen, Mohammad Minhajuddin, Randall M. Rossi, Cheryl A. Corbett, Marlene Balys, Liping Wei, Peter A. Crooks, Monica L. Guzman, Craig T. Jordan
Journal: Blood
Blood (2010) 116 (26): 5983–5990.
https://doi.org/10.1182/blood-2010-04-278044
Published: 2010
Includes: Supplemental data
Journal Articles

Chemical Derivatives of the Anti-Leukemia Stem Cell Compound 4-Benzyl-2-Methyl-1,2,4-Thiadiazolidine-3,5-Dione (TDZD-8) with Improved Activity.

Free
Monica L. Guzman, PhD, Shama Nasim, Marlene Balys, Cheryl A Corbett, Peter A Crooks, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2009) 114 (22): 3764.
https://doi.org/10.1182/blood.V114.22.3764.3764
Published: 2009
Journal Articles

Chemical Genomic Screening Reveals That PI3K/mTOR Inhibition Enhances Activity of the Anti-Leukemia Stem Cell Compound Parthenolide.

Free
Duane Hassane, Ph.D., Siddhartha Sen, Cheryl A Corbett, Marlene Balys, Randall M Rossi, Peter A Crooks, PhD, Monica L. Guzman, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2009) 114 (22): 388.
https://doi.org/10.1182/blood.V114.22.388.388
Published: 2009
Journal Articles

Identification of the Histone Deacetylase Inhibitor (HDACi), AR-42, as a Novel Anti-Leukemia Stem Cell Agent in Acute Myeloid Leukemia (AML).

Free
Duane Hassane, PhD, Marlene Balys, Guido Marcucci, M.D., John C. Byrd, Craig T. Jordan, PhD, Monica L. Guzman, PhD
Journal: Blood
Blood (2009) 114 (22): 2070.
https://doi.org/10.1182/blood.V114.22.2070.2070
Published: 2009
Journal Articles

Inhibition of Human Lymphoma Cell Growth by the PKC-Beta Selective Inhibitor Enzastaurin (LY317615) in Combination with Multiple Therapeutic Agents.

Free
Randall M Rossi, Marlene Balys, Dean Franklin, Valerie Grose, Richard I Fisher, Craig Jordan
Journal: Blood
Blood (2008) 112 (11): 1595.
https://doi.org/10.1182/blood.V112.11.1595.1595
Published: 2008
Journal Articles

Transgenes Targeted to the HPRT Locus and Expressed from a Tetracycline-Inducible Promoter Are Silenced during Embryonic Stem Cell Differentiation.

Free
Laurie A. Milner, MD, Michael Kyba, PhD, George Q. Daley, MD, PhD, Marlene Balys, MS
Journal: Blood
Blood (2005) 106 (11): 3618.
https://doi.org/10.1182/blood.V106.11.3618.3618
Published: 2005