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Peter A. Crooks
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Journal Articles

The NF-KB Inhibitor DMAPT in Combination with Ruxolitinib Displays Efficacy in Jak2V617F Knock-in Mouse Model of Myeloproliferative Neoplasms

Yue Yang, BS, Dipmoy Nath, PhD, Avik Dutta, MSc, Peter A Crooks, PhD, Golam Mohi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1783.
https://doi.org/10.1182/blood-2018-99-120195
Published: 2018
Journal Articles

The Acrylonitrile Analog, VJ-289 Ablates Acute Myelogenous Leukemia Blast, Progenitor and Stem Cell Populations by Inducing Tubulin Acetylation and Caspase Activation

Hongliang Zong, MD, PhD, Narsimha Reddy Penthala, PhD, Siddhartha Sen, PhD, Sarah Brennan, PhD, Vijayakumar Sonar, PhD, Peter A. Crooks, PhD, Monica L. Guzman, PhD
Journal: Blood
Blood (2011) 118 (21): 2496.
https://doi.org/10.1182/blood.V118.21.2496.2496
Published: 2011
Journal Articles

Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways

Duane C. Hassane, Siddhartha Sen, Mohammad Minhajuddin, Randall M. Rossi, Cheryl A. Corbett, Marlene Balys, Liping Wei, Peter A. Crooks, Monica L. Guzman, Craig T. Jordan
Journal: Blood
Blood (2010) 116 (26): 5983–5990.
https://doi.org/10.1182/blood-2010-04-278044
Published: 2010
Includes: Supplemental data
Journal Articles

Chemical Genomic Screening Reveals That PI3K/mTOR Inhibition Enhances Activity of the Anti-Leukemia Stem Cell Compound Parthenolide.

Duane Hassane, Ph.D., Siddhartha Sen, Cheryl A Corbett, Marlene Balys, Randall M Rossi, Peter A Crooks, PhD, Monica L. Guzman, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2009) 114 (22): 388.
https://doi.org/10.1182/blood.V114.22.388.388
Published: 2009
Journal Articles

Chemical Derivatives of the Anti-Leukemia Stem Cell Compound 4-Benzyl-2-Methyl-1,2,4-Thiadiazolidine-3,5-Dione (TDZD-8) with Improved Activity.

Monica L. Guzman, PhD, Shama Nasim, Marlene Balys, Cheryl A Corbett, Peter A Crooks, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2009) 114 (22): 3764.
https://doi.org/10.1182/blood.V114.22.3764.3764
Published: 2009
Journal Articles

Analysis of the Anti-Leukemia Mechanism of Parthenolide.

ShanShan Pei, Monica L. Guzman, PhD, Shama Nasim, Lei Shi, Peter A Crooks, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2009) 114 (22): 2734.
https://doi.org/10.1182/blood.V114.22.2734.2734
Published: 2009
Journal Articles

Dimethylaminoparthenolide (DMAPT) in Multiple Myeloma

Colin D. Crean, Genglin Zhang, Karen E. Pollok, PhD, Anthony L. Sinn, Peter A Crooks, PhD, Sherif Farag, MBBS, PhD, Rafat Abonour, Attaya Suvannasankha, MD
Journal: Blood
Blood (2008) 112 (11): 3672.
https://doi.org/10.1182/blood.V112.11.3672.3672
Published: 2008
Journal Articles

The NF-κB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

Saman Hewamana, Suhair Alghazal, Thet Thet Lin, Matthew Clement, Chris Jenkins, Monica L. Guzman, Craig T. Jordan, Sundar Neelakantan, Peter A. Crooks, Alan K. Burnett, Guy Pratt, Chris Fegan, Clare Rowntree, Paul Brennan, Chris Pepper
Journal: Blood
Blood (2008) 111 (9): 4681–4689.
https://doi.org/10.1182/blood-2007-11-125278
Published: 2008
Journal Articles

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

Monica L. Guzman, Randall M. Rossi, Sundar Neelakantan, Xiaojie Li, Cheryl A. Corbett, Duane C. Hassane, Michael W. Becker, John M. Bennett, Edmund Sullivan, Joshua L. Lachowicz, Andrew Vaughan, Christopher J. Sweeney, William Matthews, Martin Carroll, Jane L. Liesveld, Peter A. Crooks, Craig T. Jordan
Journal: Blood
Blood (2007) 110 (13): 4427–4435.
https://doi.org/10.1182/blood-2007-05-090621
Published: 2007
Includes: Supplemental data
Journal Articles

A Novel Orally Available Parthenolide Analog Selectively Eradicates AML Stem and Progenitor Cells.

Monica L. Guzman, PhD, Randall M. Rossi, MS, Xiaojie Li, BS, Cheryl Corbett, BS, Duane C. Hassane, PhD, Timothy Bushnell, PhD, Martin Carroll, MD, Edmund Sullivan, DVM, Sundar Neelakantan, PhD, Peter A. Crooks, PhD, Craig T. Jordan, PhD
Journal: Blood
Blood (2006) 108 (11): 237.
https://doi.org/10.1182/blood.V108.11.237.237
Published: 2006