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Journal Articles

Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data

Duane C. Hassane, Monica L. Guzman, Cheryl Corbett, Xiaojie Li, Ramzi Abboud, Fay Young, Jane L. Liesveld, Martin Carroll, Craig T. Jordan

Blood (2008) 111 (12): 5654–5662.

https://doi.org/10.1182/blood-2007-11-126003

Published: 2008

Includes: Supplemental data

Journal Articles

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

Monica L. Guzman, Randall M. Rossi, Sundar Neelakantan, Xiaojie Li, Cheryl A. Corbett, Duane C. Hassane, Michael W. Becker, John M. Bennett, Edmund Sullivan, Joshua L. Lachowicz, Andrew Vaughan, Christopher J. Sweeney, William Matthews, Martin Carroll, Jane L. Liesveld, Peter A. Crooks, Craig T. Jordan

Blood (2007) 110 (13): 4427–4435.

https://doi.org/10.1182/blood-2007-05-090621

Published: 2007

Includes: Supplemental data

Journal Articles

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

Monica L. Guzman, Xiaojie Li, Cheryl A. Corbett, Randall M. Rossi, Timothy Bushnell, Jane L. Liesveld, Josée Hébert, Fay Young, Craig T. Jordan

Blood (2007) 110 (13): 4436–4444.

https://doi.org/10.1182/blood-2007-05-088815

Published: 2007

Includes: Supplemental data

Journal Articles

A Search of Public Gene Expression Microarray Data Identifies Novel Agents That Selectively Eradicate AML Stem Cells.

Duane C. Hassane, PhD, Monica L. Guzman, PhD, Cheryl Corbett, Xiaojie Li, MD, Jane L. Liesveld, MD, Fay Young, MD, Martin Carroll, MD, Craig T. Jordan, PhD

Blood (2007) 110 (11): 776.

https://doi.org/10.1182/blood.V110.11.776.776

Published: 2007

Journal Articles

Rapid Loss of Membrane Integrity and Irreversible Commitment to Cell Death of Primary AML Stem Cells: A Novel Activity for 4-benzyl, 2-methyl,1,2,4-Thiadiazolidine,3,5 Dione (TDZD-8).

Monica L. Guzman, PhD, Xiaojie Li, BS, Cheryl Corbett, BS, Randall M. Rossi, MS, Timothy Bushnell, PhD, Craig T. Jordan, PhD

Blood (2006) 108 (11): 2535.

https://doi.org/10.1182/blood.V108.11.2535.2535

Published: 2006

Journal Articles

A Novel Orally Available Parthenolide Analog Selectively Eradicates AML Stem and Progenitor Cells.

Monica L. Guzman, PhD, Randall M. Rossi, MS, Xiaojie Li, BS, Cheryl Corbett, BS, Duane C. Hassane, PhD, Timothy Bushnell, PhD, Martin Carroll, MD, Edmund Sullivan, DVM, Sundar Neelakantan, PhD, Peter A. Crooks, PhD, Craig T. Jordan, PhD

Blood (2006) 108 (11): 237.

https://doi.org/10.1182/blood.V108.11.237.237

Published: 2006

Journal Articles

Molecular Signature for Parthenolide-Induced Apoptosis in AML CD34+ Cells Reveals Targets for Improving Induction of Leukemia-Specific Cell Death.

Duane C. Hassane, PhD, Monica L. Guzman, PhD, Xiaojie Li, MS, Cheryl Corbett, BS, Craig T. Jordan, PhD

Blood (2006) 108 (11): 2592.

https://doi.org/10.1182/blood.V108.11.2592.2592

Published: 2006

Journal Articles

Mechanisms Controlling Selective Death of Leukemia Stem Cells in Response to Parthenolide.

Monica L. Guzman, PhD, Xiaojie Li, Cheryl Corbett, Duane C. Hassane, PhD, Craig T. Jordan, PhD

Blood (2005) 106 (11): 467.

https://doi.org/10.1182/blood.V106.11.467.467

Published: 2005

Journal Articles

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

Monica L. Guzman, Randall M. Rossi, Lilliana Karnischky, Xiaojie Li, Derick R. Peterson, Dianna S. Howard, Craig T. Jordan

Blood (2005) 105 (11): 4163–4169.

https://doi.org/10.1182/blood-2004-10-4135

Published: 2005

Journal Articles

Selective Induction of Apoptosis in Acute Myelogenous Leukemia Stem Cells by the Novel Agent Parthenolide.

Monica L. Guzman, PhD, Lilliana Karnischky, Xiaojie Li, Sarah J. Neering, MS, Randal M. Rossi, Craig T. Jordan, PhD

Blood (2004) 104 (11): 2542.

https://doi.org/10.1182/blood.V104.11.2542.2542

Published: 2004

NARROW

Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

A Search of Public Gene Expression Microarray Data Identifies Novel Agents That Selectively Eradicate AML Stem Cells.

Rapid Loss of Membrane Integrity and Irreversible Commitment to Cell Death of Primary AML Stem Cells: A Novel Activity for 4-benzyl, 2-methyl,1,2,4-Thiadiazolidine,3,5 Dione (TDZD-8).

A Novel Orally Available Parthenolide Analog Selectively Eradicates AML Stem and Progenitor Cells.

Molecular Signature for Parthenolide-Induced Apoptosis in AML CD34+ Cells Reveals Targets for Improving Induction of Leukemia-Specific Cell Death.

Mechanisms Controlling Selective Death of Leukemia Stem Cells in Response to Parthenolide.

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

Selective Induction of Apoptosis in Acute Myelogenous Leukemia Stem Cells by the Novel Agent Parthenolide.

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American Society of Hematology

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American Society of Hematology

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