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Martin Clynes
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Journal Articles

Examining the Impact of Altered Protein Expression and Ubiquitination Levels on the Development of Resistance to Proteasome Inhibitors Using Proteomics Analysis

Paul Dowling, Kay Reen Ting, Justine Meiller, Shane Kelly, Martin Clynes, Peter O'Gorman
Journal: Blood
Blood (2015) 126 (23): 4208.
https://doi.org/10.1182/blood.V126.23.4208.4208
Published: 2015
Journal Articles

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

Kerstin Pohl, Elaine Hayes, Joanne Keenan, Michael Henry, Paula Meleady, Kevin Molloy, Bakr Jundi, David A. Bergin, Cormac McCarthy, Oliver J. McElvaney, Michelle M. White, Martin Clynes, Emer P. Reeves, Noel G. McElvaney
Journal: Blood
Blood (2014) 124 (7): 999–1009.
https://doi.org/10.1182/blood-2014-02-555268
Published: 2014
Includes: Supplemental data
Journal Articles

Bone Turnover Biomarkers Are Useful In Monitoring Myeloma Bone Disease and As Early Predictor Biomarkers For Relapse Disease In Multiple Myeloma

Kay Reen Ting, MB Bch BAO, Abdul Hameed, MBBS, MRCP, Jennifer Brady, Paul Dowling, PhD, Colin Clarke, PhD, Justine Meiller, Constantine S. Mitsiades, MD, PhD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Martin Clynes, PhD, Peter O'Gorman, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1869.
https://doi.org/10.1182/blood.V122.21.1869.1869
Published: 2013
Journal Articles

Cells of the Osteoblast Lineage Confer Myeloma Cell Resistance to Established and Investigational Therapeutic Agents

Catriona A. Hayes, MD, Paul Dowling, PhD, Richard W.J. Groen, PhD, Douglas W. McMillin, PhD, Jake E. Delmore, Hannah M. Jacobs, Niels W.C.J. van de Donk, MD, PhD, Eugen Dhimolea, PhD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Martin Clynes, PhD, Peter O'Gorman, M.D., Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3995.
https://doi.org/10.1182/blood.V120.21.3995.3995
Published: 2012
Journal Articles

Proteomic Characterization of An Isogenic Multiple Myeloma Cell Line Model of Bortezomib Resistance

*Catriona A. Hayes, MD, *Paul Dowling, PhD, Joseph Negri, Michael Henry, Leutz Buon, Jana Jakubikova, PhD, Jake E Delmore, Douglas W. McMillin, PhD, Steffen Klippel, PhD, Hannah M. Jacobs, Niels W.C.J. van de Donk, MD, PhD, Eugen Dhimolea, PhD, Panisinee Lawasut, MD, MSc, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Martin Clynes, PhD, *Peter O Gorman, MD, PhD, *Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1820.
https://doi.org/10.1182/blood.V118.21.1820.1820
Published: 2011
Journal Articles

The Interaction of Bortezomib with P-Gp, MRP-1 and BCRP Drug Transporters: Implications for Therapeutic Applications of Bortezomib in Advanced Multiple Myeloma and Other Neoplasias.

Melissa G Ooi, M.D., Robert O'Connor, Ph.D, Jana Jakubikova, Ph.D, Justine Meiller, Diploma, in, Biochemistry, Degre, Steffen Klippel, Ph.D, Jake Delmore, Efstathios Kastritis, M.D, Douglas McMillin, Ph.D, Martin Clynes, Ph.D, Paul Richardson, M.D., Constantine S. Mitsiades, M.D., Ph.D, Peter O'Gorman, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2009) 114 (22): 1729.
https://doi.org/10.1182/blood.V114.22.1729.1729
Published: 2009
Journal Articles

A Panel of POTENTIAL PROTEIN BIOMARKERS for Predicting CLINICAL RESPONSE to Thalidomide IN Newly Diagnosed MULTIPLE MYELOMA PATIENTS.

Rajesh Rajpal, Paul Dowling, Justine Meiller, William G Murphy, Kenneth C. Anderson, MD, Philip Murphy, Robert O Connor, Martin Clynes, Peter O'Gorman, M.D.
Journal: Blood
Blood (2009) 114 (22): 4882.
https://doi.org/10.1182/blood.V114.22.4882.4882
Published: 2009
Journal Articles

Proteomics as a Functional Tool in Evaluating Bortezomib Treatment and Drug Resistance Mechanism.

Melissa G Ooi, M.D., Paul Dowling, Ph.D, Paul Richardson, M.D., Constantine S. Mitsiades, M.D., Ph.D, Martin Clynes, Ph.D, Kenneth C. Anderson, Peter O'Gorman, M.D.
Journal: Blood
Blood (2009) 114 (22): 1805.
https://doi.org/10.1182/blood.V114.22.1805.1805
Published: 2009
Journal Articles

Prediction of Thalidomide Response in the Newly Diagnosed Untreated Multiple Myeloma Patients Based on a Panel of Protein Biomarkers

Rajpal Rajpal, Paul Dowling, Justine Meiller, Kenneth C Anderson, MD, Philip Murphy, Martin Clynes, Peter O’Gorman
Journal: Blood
Blood (2008) 112 (11): 5018.
https://doi.org/10.1182/blood.V112.11.5018.5018
Published: 2008