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Journal Articles

Dabigatran Etexilate in Children with Venous Thromboembolism: Results of the Open-Label, Phase IIb/III, Randomized Diversity Clinical Trial

Jacqueline Halton, MD, Leonardo R. Brandao, MD, Matteo Luciani, MD, Lisa Bomgaars, MD, Elizabeth Chalmers, MD, Lesley Mitchell, MD, Ildar Nurmeev, MD, Anjali Sharathkumar, MD, Pavel Svirin, MD, Kirill Gorbatikov, MD, Igor Tartakovsky, MD, Monika Simetzberger, DI, Fenglei Huang, PhD, Zhichao Sun, PhD, Jörg Kreuzer, MD, Savion Gropper, MD, Martina Brueckmann, MD, Manuela Albisetti, MD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-136682

Published: 2020

Journal Articles

Efficacy and Safety of Dabigatran in the Treatment and Secondary Prophylaxis of Children with Venous Thromboembolism and Thrombophilia

Leonardo R. Brandao, MD, Igor Tartakovsky, MD, Manuela Albisetti, MD, Lisa Bomgaars, MD, Elizabeth Chalmers, MD, Lesley Mitchell, MD, Matteo Luciani, MD, Paola Saracco, MD, Judy Felgenhauer, MD, Olga Lvova, MD, Monika Simetzberger, DI, Zhichao Sun, PhD, Ingrid Gergei, MD, Martina Brueckmann, MD, Jacqueline Halton, MD

Blood (2020) 136 (Supplement 1): 35–36.

https://doi.org/10.1182/blood-2020-136695

Published: 2020

Journal Articles

Safety of dabigatran etexilate for the secondary prevention of venous thromboembolism in children

Leonardo R. Brandão, Manuela Albisetti, Jacqueline Halton, Lisa Bomgaars, Elizabeth Chalmers, Lesley G. Mitchell, Ildar Nurmeev, Pavel Svirin, Tomas Kuhn, Ondrej Zapletal, Igor Tartakovsky, Monika Simetzberger, Fenglei Huang, Zhichao Sun, Jörg Kreuzer, Savion Gropper, Martina Brueckmann, Matteo Luciani

Blood (2020) 135 (7): 491–504.

https://doi.org/10.1182/blood.2019000998

Published: 2020

Includes: Supplemental data

Journal Articles

Pharmacokinetics (PK) and Pharmacodynamics (PD), Safety and Tolerability of a Single-Dose Oral Solution of Dabigatran Etexilate Given after Standard Anticoagulant Therapy in Children from Birth to Less Than One Year Old, with Venous Thromboembolism

Jacqueline ML Halton, MD, Anne-Caroline Picard, Ruth Harper, Fenglei Huang, Martina Brueckmann, MD, Savion Gropper, MD, Hugo Maas, Igor Tartakovsky, MD, Ildar Nurmeev, Lesley G Mitchell, Leonardo R. Brandão, MD MSc, Manuela Albisetti, MD

Blood (2016) 128 (22): 1441.

https://doi.org/10.1182/blood.V128.22.1441.1441

Published: 2016

Journal Articles

Rationale and Design of a Phase III Safety Trial of Idarucizumab in Children Receiving Dabigatran Etexilate for the Treatment and Secondary Prevention of Venous Thromboembolism

Manuela Albisetti, MD, Arno Schlosser, MSc, Martina Brueckmann, MD, Savion Gropper, MD, Stephan Glund, PhD, Igor Tartakovsky, MD, Leonardo R. Brandão, MD MSc, Paul A Reilly, PhD

Blood (2016) 128 (22): 5010.

https://doi.org/10.1182/blood.V128.22.5010.5010

Published: 2016

Journal Articles

Rationale and Design of a Phase IIb/III Open-Label, Multicenter Study of Dabigatran Etexilate for Venous Thromboembolism in Children: The Diversity Study

Manuela Albisetti, MD, Ivan Manastirski, Martina Brueckmann, MD, Savion Gropper, MD, Bushi Wang, Igor Tartakovsky, MD, Branislav Biss, Fenglei Huang, Lesley G Mitchell, MSc, Leonardo R. Brandão, MD MSc, Jacqueline ML Halton, MD

Blood (2016) 128 (22): 5025.

https://doi.org/10.1182/blood.V128.22.5025.5025

Published: 2016

Journal Articles

Rationale and Design of a Phase III Single-Arm Multicenter Study of Dabigatran Etexilate for the Secondary Prevention of Venous Thromboembolism in Children

Matteo Luciani, Manuela Albisetti, MD, Ivan Manastirski, Martina Brueckmann, MD, Savion Gropper, MD, Igor Tartakovsky, MD, Bushi Wang, Branislav Biss, Lesley G Mitchell, Fenglei Huang, Jacqueline ML Halton, MD, Leonardo R. Brandão, MD MSc

Blood (2016) 128 (22): 5028.

https://doi.org/10.1182/blood.V128.22.5028.5028

Published: 2016

Journal Articles

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a Single-Dose Oral Solution of Dabigatran Given after Standard Anticoagulant Therapy in Children (Two Age Groups: 1-<2 and 2-<12 Years Old), with Venous Thromboembolism

Jacqueline ML Halton, MD, Manuela Albisetti, MD, Matteo Luciani, Fenglei Huang, Branislav Biss, Martina Brueckmann, MD, Savion Gropper, MD, Hugo Maas, Igor Tartakovsky, MD, Lesley G Mitchell

Blood (2016) 128 (22): 87.

https://doi.org/10.1182/blood.V128.22.87.87

Published: 2016

Journal Articles

Real-World Study of Dabigatran Etexilate for Thromboprophylaxis in Over 5000 Hip or Knee Replacement Patients: Favourable Safety Profile in Subgroups with Different BMI, Renal Function and Age

Nadia Rosencher, MD, Simon Frostick, MD, Martin Feuring, MD, Eva Kleine, Martina Brueckmann, MD, Andreas Clemens, MD, Charles Marc Samama, MD

Blood (2012) 120 (21): 1160.

https://doi.org/10.1182/blood.V120.21.1160.1160

Published: 2012

Journal Articles

Epidemiological Data On the Incidence of Co-Morbidities and Co-Medications in Patients Undergoing Total Hip or Knee Replacement Surgery: Real-World Study and Phase III Clinical Trials.

Nadia Rosencher, MD, Simon Frostick, MD, Martin Feuring, MD, Eva Kleine, Martina Brueckmann, MD, Andreas Clemens, MD, Charles Marc Samama, MD

Blood (2012) 120 (21): 2269.

https://doi.org/10.1182/blood.V120.21.2269.2269

Published: 2012

Journal Articles

Management and Outcomes of Major Bleeding On Dabigatran or Warfarin

Ammar Majeed, Hun-Gyu Hwang, Martina Brueckmann, MD, Stuart Connolly, MD, John Eikelboom, Michael Ezekowitz, MB, ChB, DPhil, Lars Wallentin, MD, PhD, Salim Yusuf, FRCPC, DPhil, Sam Schulman, MD, PhD

Blood (2012) 120 (21): 19.

https://doi.org/10.1182/blood.V120.21.19.19

Published: 2012

NARROW

Dabigatran Etexilate in Children with Venous Thromboembolism: Results of the Open-Label, Phase IIb/III, Randomized Diversity Clinical Trial

Efficacy and Safety of Dabigatran in the Treatment and Secondary Prophylaxis of Children with Venous Thromboembolism and Thrombophilia

Safety of dabigatran etexilate for the secondary prevention of venous thromboembolism in children

Pharmacokinetics (PK) and Pharmacodynamics (PD), Safety and Tolerability of a Single-Dose Oral Solution of Dabigatran Etexilate Given after Standard Anticoagulant Therapy in Children from Birth to Less Than One Year Old, with Venous Thromboembolism

Rationale and Design of a Phase III Safety Trial of Idarucizumab in Children Receiving Dabigatran Etexilate for the Treatment and Secondary Prevention of Venous Thromboembolism

Rationale and Design of a Phase IIb/III Open-Label, Multicenter Study of Dabigatran Etexilate for Venous Thromboembolism in Children: The Diversity Study

Rationale and Design of a Phase III Single-Arm Multicenter Study of Dabigatran Etexilate for the Secondary Prevention of Venous Thromboembolism in Children

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a Single-Dose Oral Solution of Dabigatran Given after Standard Anticoagulant Therapy in Children (Two Age Groups: 1-<2 and 2-<12 Years Old), with Venous Thromboembolism

Real-World Study of Dabigatran Etexilate for Thromboprophylaxis in Over 5000 Hip or Knee Replacement Patients: Favourable Safety Profile in Subgroups with Different BMI, Renal Function and Age

Epidemiological Data On the Incidence of Co-Morbidities and Co-Medications in Patients Undergoing Total Hip or Knee Replacement Surgery: Real-World Study and Phase III Clinical Trials.

Management and Outcomes of Major Bleeding On Dabigatran or Warfarin

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American Society of Hematology

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American Society of Hematology

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